| Identification |
|---|
| HMDB Protein ID
| CDBP01992 |
| Secondary Accession Numbers
| Not Available |
| Name
| Recoverin |
| Description
| Not Available |
| Synonyms
|
- Cancer-associated retinopathy protein
- Protein CAR
|
| Gene Name
| RCVRN |
| Protein Type
| Metal Binding |
| Biological Properties |
|---|
| General Function
| Involved in calcium ion binding |
| Specific Function
| Seems to be implicated in the pathway from retinal rod guanylate cyclase to rhodopsin. May be involved in the inhibition of the phosphorylation of rhodopsin in a calcium-dependent manner. The calcium-bound recoverin prolongs the photoresponse |
| GO Classification
|
| Function |
| ion binding |
| cation binding |
| metal ion binding |
| binding |
| calcium ion binding |
|
| Cellular Location
|
Not Available
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 17p13.1 |
| SNPs
| RCVRN |
| Gene Sequence
|
>603 bp
ATGGGGAACAGCAAAAGTGGGGCCCTGTCCAAGGAGATCCTGGAGGAGCTGCAGCTGAAC
ACCAAGTTCTCGGAGGAGGAGCTGTGCTCCTGGTACCAGTCCTTCCTGAAGGACTGTCCC
ACCGGCCGCATCACCCAGCAGCAGTTCCAGAGCATCTACGCCAAGTTCTTCCCCGACACC
GACCCCAAGGCCTACGCCCAGCATGTGTTCCGCAGCTTCGATTCCAACCTCGACGGCACC
CTGGACTTCAAGGAGTACGTCATCGCCCTGCACATGACCACCGCGGGCAAGACCAACCAG
AAGCTGGAGTGGGCCTTCTCCCTCTACGACGTGGACGGTAACGGGACCATCAGCAAGAAT
GAAGTGCTGGAGATCGTCATGGCTATTTTCAAAATGATCACTCCCGAGGACGTGAAGCTC
CTTCCAGACGATGAAAACACGCCGGAAAAGCGAGCCGAGAAGATCTGGAAGTACTTTGGA
AAGAATGATGATGATAAACTTACAGAGAAAGAATTCATTGAGGGGACACTGGCCAATAAG
GAAATTCTGCGACTGATCCAGTTTGAGCCTCAAAAAGTGAAGGAAAAGATGAAGAACGCC
TGA
|
| Protein Properties |
|---|
| Number of Residues
| 200 |
| Molecular Weight
| 23130.1 |
| Theoretical pI
| 4.79 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Recoverin
MGNSKSGALSKEILEELQLNTKFSEEELCSWYQSFLKDCPTGRITQQQFQSIYAKFFPDT
DPKAYAQHVFRSFDSNLDGTLDFKEYVIALHMTTAGKTNQKLEWAFSLYDVDGNGTISKN
EVLEIVMAIFKMITPEDVKLLPDDENTPEKRAEKIWKYFGKNDDDKLTEKEFIEGTLANK
EILRLIQFEPQKVKEKMKNA
|
| External Links |
|---|
| GenBank ID Protein
| 1902890 |
| UniProtKB/Swiss-Prot ID
| P35243 |
| UniProtKB/Swiss-Prot Entry Name
| RECO_HUMAN |
| PDB IDs
|
|
| GenBank Gene ID
| AB001838 |
| GeneCard ID
| RCVRN |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |