Showing Protein Galectin-1 (CDBP01937)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 1 compounds
Identification
HMDB Protein ID CDBP01937
Secondary Accession Numbers Not Available
Name Galectin-1
Description Not Available
Synonyms
  1. 14 kDa lectin
  2. Beta-galactoside- binding lectin L-14-I
  3. Galaptin
  4. HBL
  5. HPL
  6. Lactose-binding lectin 1
  7. Lectin galactoside-binding soluble 1
  8. Putative MAPK-activating protein MP12
  9. S-Lac lectin 1
Gene Name LGALS1
Protein Type Enzyme
Biological Properties
General Function Not Available
Specific Function May regulate cell apoptosis and cell differentiation. Binds beta-galactoside. Binds CD45, CD3 and CD4. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase
GO Classification
Function
binding
carbohydrate binding
sugar binding
Cellular Location
  1. Cytoplasm
Pathways
Gene Properties
Chromosome Location Chromosome:22
Locus 22q13.1
SNPs LGALS1
Gene Sequence 
>408 bp
ATGGCTTGTGGTCTGGTCGCCAGCAACCTGAATCTCAAACCTGGAGAGTGCCTTCGAGTG
CGAGGCGAGGTGGCTCCTGACGCTAAGAGCTTCGTGCTGAACCTGGGCAAAGACAGCAAC
AACCTGTGCCTGCACTTCAACCCTCGCTTCAACGCCCACGGCGACGCCAACACCATCGTG
TGCAACAGCAAGGACGGCGGGGCCTGGGGGACCGAGCAGCGGGAGGCTGTCTTTCCCTTC
CAGCCTGGAAGTGTTGCAGAGGTGTGCATCACCTTCGACCAGGCCAACCTGACCGTCAAG
CTGCCAGATGGATACGAATTCAAGTTCCCCAACCGCCTCAACCTGGAGGCCATCAACTAC
ATGGCAGCTGACGGTGACTTCAAGATCAAATGTGTGGCCTTTGACTGA
Protein Properties
Number of Residues 135
Molecular Weight 14716.0
Theoretical pI 5.15
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["None"]
Protein Sequence 
>Galectin-1
MACGLVASNLNLKPGECLRVRGEVAPDAKSFVLNLGKDSNNLCLHFNPRFNAHGDANTIV
CNSKDGGAWGTEQREAVFPFQPGSVAEVCITFDQANLTVKLPDGYEFKFPNRLNLEAINY
MAADGDFKIKCVAFD
GenBank ID Protein 34343
UniProtKB/Swiss-Prot ID P09382
UniProtKB/Swiss-Prot Entry Name LEG1_HUMAN
PDB IDs
GenBank Gene ID X14829
GeneCard ID LGALS1
GenAtlas ID LGALS1
HGNC ID HGNC:6561
References
General References Not Available