Showing Protein Eosinophil cationic protein precursor (CDBP01885)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 0 compounds
Identification
HMDB Protein ID CDBP01885
Secondary Accession Numbers Not Available
Name Eosinophil cationic protein precursor
Description Not Available
Synonyms
  1. ECP
  2. RNase 3
  3. Ribonuclease 3
Gene Name RNASE3
Protein Type Enzyme
Biological Properties
General Function Not Available
Specific Function Cytotoxin and helminthotoxin with low-efficiency ribonuclease activity. Possesses a wide variety of biological activities. Exhibits antibacterial activity
GO Classification
Function
endonuclease activity
endoribonuclease activity
endoribonuclease activity, producing 3'-phosphomonoesters
pancreatic ribonuclease activity
hydrolase activity, acting on ester bonds
binding
catalytic activity
hydrolase activity
nucleic acid binding
nuclease activity
Cellular Location
  1. Secreted
Pathways
Gene Properties
Chromosome Location Chromosome:14
Locus 14q24-q31
SNPs RNASE3
Gene Sequence 
>483 bp
ATGGTTCCAAAACTGTTCACTTCCCAAATTTGTCTGCTTCTTCTGTTGGGGCTTATGGGT
GTGGAGGGCTCACTCCATGCCAGACCCCCACAGTTTACGAGGGCTCAGTGGTTTGCCATC
CAGCACATCAGTCTGAACCCCCCTCGATGCACCATTGCAATGCGGGCAATTAACAATTAT
CGATGGCGTTGCAAAAACCAAAATACTTTTCTTCGTACAACTTTTGCTAATGTAGTTAAT
GTTTGTGGTAACCAAAGTATACGCTGCCCTCATAACAGAACTCTCAACAATTGTCATCGG
AGTAGATTCCGGGTGCCTTTACTCCACTGTGACCTCATAAATCCAGGTGCACAGAATATT
TCAAACTGCAGGTATGCAGACAGACCAGGAAGGAGGTTCTATGTAGTTGCATGTGACAAC
AGAGATCCACGGGATTCTCCACGGTATCCTGTGGTTCCAGTTCACCTGGATACCACCATC
TAA
Protein Properties
Number of Residues 160
Molecular Weight 18386.0
Theoretical pI 10.33
Pfam Domain Function
Signals
  • ["1-27"]
Transmembrane Regions Not Available
Protein Sequence 
>Eosinophil cationic protein precursor
MVPKLFTSQICLLLLLGLMGVEGSLHARPPQFTRAQWFAIQHISLNPPRCTIAMRAINNY
RWRCKNQNTFLRTTFANVVNVCGNQSIRCPHNRTLNNCHRSRFRVPLLHCDLINPGAQNI
SNCTYADRPGRRFYVVACDNRDPRDSPRYPVVPVHLDTTI
GenBank ID Protein 31077
UniProtKB/Swiss-Prot ID P12724
UniProtKB/Swiss-Prot Entry Name ECP_HUMAN
PDB IDs
GenBank Gene ID X15161
GeneCard ID RNASE3
GenAtlas ID RNASE3
HGNC ID HGNC:10046
References
General References Not Available