| Identification |
|---|
| HMDB Protein ID
| CDBP01884 |
| Secondary Accession Numbers
| Not Available |
| Name
| Keratocan |
| Description
| Not Available |
| Synonyms
|
- KTN
- Keratan sulfate proteoglycan keratocan
|
| Gene Name
| KERA |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in protein binding |
| Specific Function
| May be important in developing and maintaining corneal transparency and for the structure of the stromal matrix |
| GO Classification
|
| Function |
| binding |
| protein binding |
|
| Cellular Location
|
- Secreted
- extracellular space
- extracellular matrix
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 12q22 |
| SNPs
| KERA |
| Gene Sequence
|
>1059 bp
ATGGCAGGCACAATCTGTTTCATCATGTGGGTGTTATTCATAACAGACACTGTGTGGTCT
AGAAGTGTAAGGCAGGTCTATGAAGTACATGATTCAGATGATTGGACTATTCATGACTTC
GAGTGTCCCATGGAATGTTTCTGCCCACCCAGTTTTCCTACTGCTTTATATTGTGAAAAT
AGAGGTCTCAAAGAAATTCCTGCTATTCCTTCAAGAATTTGGTATCTTTATCTTCAAAAC
AACCTGATAGAAACCATTCCTGAGAAGCCATTCGAGAATGCCACCCAGCTAAGATGGATA
AATCTAAATAAGAACAAAATAACCAACTACGGAATTGAAAAAGGAGCCCTAAGCCAGCTG
AAGAAGTTGCTCTTCTTATTTCTGGAAGATAATGAGCTAGAGGAGGTACCTTCTCCATTG
CCAAGAAGTTTAGAACAATTACAATTAGCTAGAAATAAGGTGTCCAGAATTCCTCAAGGG
ACCTTTAGCAATCTGGAGAACCTGACCCTTCTTGACCTACAGAACAACAAATTAGTGGAC
AATGCCTTTCAAAGAGACACTTTTAAAGGACTCAAGAATCTCATGCAGCTAAACATGGCC
AAGAATGCCCTGAGGAATATGCCTCCAAGATTACCAGCCAATACAATGCAGTTGTTTTTA
GACAACAATTCCATTGAAGGAATACCAGAAAATTATTTTAATGTGATTCCTAAAGTGGCC
TTTTTGAGACTAAATCACAACAAACTGTCAGATGAGGGTCTCCCATCAAGAGGATTTGAT
GTATCATCAATTCTAGATCTTCAACTGTCGCACAATCAACTCACAAAGGTTCCCCGAATC
AGTGCTCATCTGCAGCACCTTCACCTTGATCATAACAAAATTAAAAGTGTGAATGTCTCT
GTAATATGTCCCAGCCCATCCATGCTGCCTGCAGAACGAGATTCCTTCAGTTATGGACCT
CATCTTCGCTACCTCCGTCTGGATGGAAATGAAATCAAACCACCAATTCCAATGGCTTTA
ATGACCTGCTTCAGACTTCTGCAGGCTGTCATTATTTAA
|
| Protein Properties |
|---|
| Number of Residues
| 352 |
| Molecular Weight
| 40508.5 |
| Theoretical pI
| 7.53 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Keratocan
MAGTICFIMWVLFITDTVWSRSVRQVYEVHDSDDWTIHDFECPMECFCPPSFPTALYCEN
RGLKEIPAIPSRIWYLYLQNNLIETIPEKPFENATQLRWINLNKNKITNYGIEKGALSQL
KKLLFLFLEDNELEEVPSPLPRSLEQLQLARNKVSRIPQGTFSNLENLTLLDLQNNKLVD
NAFQRDTFKGLKNLMQLNMAKNALRNMPPRLPANTMQLFLDNNSIEGIPENYFNVIPKVA
FLRLNHNKLSDEGLPSRGFDVSSILDLQLSHNQLTKVPRISAHLQHLHLDHNKIKSVNVS
VICPSPSMLPAERDSFSYGPHLRYLRLDGNEIKPPIPMALMTCFRLLQAVII
|
| External Links |
|---|
| GenBank ID Protein
| 3132827 |
| UniProtKB/Swiss-Prot ID
| O60938 |
| UniProtKB/Swiss-Prot Entry Name
| KERA_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AF063301 |
| GeneCard ID
| KERA |
| GenAtlas ID
| KERA |
| HGNC ID
| HGNC:6309 |
| References |
|---|
| General References
| Not Available |