Showing Protein Feline leukemia virus subgroup C receptor-related protein 1 (CDBP01883)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 1 compounds
Identification
HMDB Protein ID CDBP01883
Secondary Accession Numbers Not Available
Name Feline leukemia virus subgroup C receptor-related protein 1
Description Not Available
Synonyms
  1. Feline leukemia virus subgroup C receptor
  2. hFLVCR
Gene Name FLVCR1
Protein Type Receptor
Biological Properties
General Function Involved in transmembrane transport
Specific Function Exports cytoplasmic heme. May be required to protect developing erythroid cells from heme toxicity. Causes susceptibility to FeLV-C in vitro
GO Classification
Process
establishment of localization
transport
transmembrane transport
Cellular Location
  1. Cell membrane
  2. Multi-pass membrane protein
Pathways
Gene Properties
Chromosome Location Chromosome:1
Locus 1q32.3
SNPs FLVCR1
Gene Sequence 
>1668 bp
ATGGCGCGGCCAGACGATGAGGAGGGGGCGGCGGTGGCGCCCGGACACCCGCTCGCGAAA
GGATACCTCCCGTTGCCGAGGGGCGCGCCCGTTGGGAAGGAGAGCGTGGAGCTGCAGAAC
GGGCCCAAAGCGGGCACCTTCCCGGTGAATGGGGCCCCCCGGGACAGCCTCGCTGCCGCC
TCGGGAGTTCTGGGCGGGCCTCAGACTCCACTGGCCCCAGAAGAGGAGACCCAGGCCCGG
CTGCTGCCTGCGGGCGCGGGAGCTGAGACCCCGGGGGCCGAGAGCAGCCCGCTGCCCCTT
ACGGCGCTCTCCCCGCGGCGCTTCGTGGTGCTCCTGATCTTCAGCCTGTACTCGCTGGTC
AACGCCTTTCAGTGGATCCAGTACAGCATCATTAGCAACGTCTTCGAGGGCTTCTACGGT
GTCACCTTGCTGCACATCGACTGGCTGTCCATGGTGTACATGCTGGCCTACGTGCCCCTC
ATCTTCCCGGCCACCTGGCTGCTGGACACCAGAGGCCTGCGGCTCACCGCCCTGCTGGGC
TCCGGCCTCAACTGCCTGGGTGCCTGGATCAAGTGCGGCAGTGTGCAACAACATCTCTTC
TGGGTCACCATGTTGGGCCAGTGCTTGTGCTCGGTGGCCCAGGTGTTCATCCTGGGCTTG
CCCTCCCGCATCGCCTCAGTGTGGTTTGGGCCCAAAGAGGTGTCCACAGCTTGTGCCACC
GCCGTGCTGGGCAATCAGCTTGGAACTGCAGTTGGCTTTTTGCTACCACCAGTTTTAGTA
CCCAACACACAGAATGACACAAATCTCCTGGCTTGTAATATCAGCACCATGTTTTATGGA
ACATCAGCTGTTGCCACACTTTTATTTATTTTAACAGCAATTGCCTTCAAAGAAAAACCT
CGGTATCCACCAAGTCAGGCTCAAGCAGCTCTTCAAGACAGTCCCCCTGAAGAGTACTCC
TATAAGAAATCAATAAGAAACCTGTTTAAAAACATTCCTTTTGTCCTTCTGTTGATCACT
TATGGTATCATGACTGGTGCCTTTTATTCAGTCTCAACGTTATTAAATCAAATGATATTG
ACATATTATGAGGGAGAAGAAGTCAATGCTGGAAGGATTGGGCTAACGCTAGTAGTAGCT
GGAATGGTGGGCTCTATTCTTTGTGGCTTATGGCTGGATTATACTAAAACATACAAACAG
ACTACCCTGATAGTTTATATTTTGTCTTTTATTGGAATGGTTATCTTTACTTTCACATTG
GACCTTAGATATATTATCATCGTGTTTGTTACTGGAGGGGTGCTTGGCTTCTTCATGACT
GGTTACCTCCCTTTGGGTTTTGAATTTGCTGTTGAAATCACTTACCCTGAATCTGAAGGT
ACTTCATCTGGTCTTCTTAATGCTTCTGCACAGATATTTGGAATTTTGTTCACATTGGCT
CAAGGAAAGCTCACATCAGACTATGGTCCTAAGGCAGGGAACATTTTTCTCTGTGTCTGG
ATGTTTATAGGCATCATATTAACAGCATTAATCAAGTCTGATCTGCGAAGACACAACATA
AATATAGGAATTACAAATGTTGATGTTAAAGCTATACCAGCTGACAGTCCCACAGACCAA
GAACCAAAAACGGTTATGTTGTCCAAGCAGTCAGAATCAGCAATTTGA
Protein Properties
Number of Residues 555
Molecular Weight 59862.3
Theoretical pI 5.78
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["108-128", "148-168", "175-195", "200-220", "241-261", "276-296", "332-352", "373-393", "402-422", "425-445", "460-480", "491-511"]
Protein Sequence 
>Feline leukemia virus subgroup C receptor-related protein 1
MARPDDEEGAAVAPGHPLAKGYLPLPRGAPVGKESVELQNGPKAGTFPVNGAPRDSLAAA
SGVLGGPQTPLAPEEETQARLLPAGAGAETPGAESSPLPLTALSPRRFVVLLIFSLYSLV
NAFQWIQYSIISNVFEGFYGVTLLHIDWLSMVYMLAYVPLIFPATWLLDTRGLRLTALLG
SGLNCLGAWIKCGSVQQHLFWVTMLGQCLCSVAQVFILGLPSRIASVWFGPKEVSTACAT
AVLGNQLGTAVGFLLPPVLVPNTQNDTNLLACNISTMFYGTSAVATLLFILTAIAFKEKP
RYPPSQAQAALQDSPPEEYSYKKSIRNLFKNIPFVLLLITYGIMTGAFYSVSTLLNQMIL
TYYEGEEVNAGRIGLTLVVAGMVGSILCGLWLDYTKTYKQTTLIVYILSFIGMVIFTFTL
DLRYIIIVFVTGGVLGFFMTGYLPLGFEFAVEITYPESEGTSSGLLNASAQIFGILFTLA
QGKLTSDYGPKAGNIFLCVWMFIGIILTALIKSDLRRHNINIGITNVDVKAIPADSPTDQ
EPKTVMLSKQSESAI
GenBank ID Protein 5565872
UniProtKB/Swiss-Prot ID Q9Y5Y0
UniProtKB/Swiss-Prot Entry Name FLVC1_HUMAN
PDB IDs Not Available
GenBank Gene ID AF118637
GeneCard ID FLVCR1
GenAtlas ID FLVCR1
HGNC ID HGNC:24682
References
General References Not Available