| Identification |
|---|
| HMDB Protein ID
| CDBP01855 |
| Secondary Accession Numbers
| Not Available |
| Name
| C-X-C motif chemokine 16 |
| Description
| Not Available |
| Synonyms
|
- SR-PSOX
- Scavenger receptor for phosphatidylserine and oxidized low density lipoprotein
- Small-inducible cytokine B16
- Transmembrane chemokine CXCL16
|
| Gene Name
| CXCL16 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in chemokine activity |
| Specific Function
| Acts as a scavenger receptor on macrophages, which specifically binds to OxLDL (oxidized low density lipoprotein), suggesting that it may be involved in pathophysiology such as atherogenesis. Induces a strong chemotactic response. Induces calcium mobilization. Binds to CXCR6/Bonzo |
| GO Classification
|
Not Available
|
| Cellular Location
|
- Cell membrane
- Secreted
- Single-pass type I membrane protein (Potential)
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 17p13 |
| SNPs
| CXCL16 |
| Gene Sequence
|
>765 bp
ATGGGACGGGACTTGCGGCCCGGGTCCCGCGTGCTCCTGCTCCTGCTTCTGCTCCTGCTG
GTGTACCTGACTCAGCCAGGCAATGGCAACGAGGGCAGCGTCACTGGAAGTTGTTATTGT
GGTAAAAGAATTTCTTCCGACTCCCCGCCATCGGTTCAGTTCATGAATCGTCTCCGGAAA
CACCTGAGAGCTTACCATCGGTGTCTATACTACACGAGGTTCCAGCTCCTTTCCTGGAGC
GTGTGTGGGGGCAACAAGGACCCATGGGTTCAGGAATTGATGAGCTGTCTTGATCTCAAA
GAATGTGGACATGCTTACTCGGGGATTGTGGCCCACCAGAAGCATTTACTTCCTACCAGC
CCCCCAATTTCTCAGGCCTCAGAGGGGGCATCTTCAGATATCCACACCCCTGCCCAGATG
CTCCTGTCCACCTTGCAGTCCACTCAGCGCCCCACCCTCCCAGTAGGATCACTGTCCTCG
GACAAAGAGCTCACTCGTCCCAATGAAACCACCATTCACACTGCGGGCCACAGTCTGGCA
GCTGGGCCTGAGGCTGGGGAGAACCAGAAGCAGCCGGAAAAAAATGCTGGTCCCACAGCC
AGGACATCAGCCACAGTGCCGGTCCTGTGCCTCCTGGCCATCATCTTCATCCTCACCGCA
GCCCTTTCCTATGTGCTGTGCAAGAGGAGGAGGGGGCAGTCACCGCAGTCCTCTCCAGAT
CTGCCGGTTCATTATATACCTGTGGCACCTGACTCTAATACCTGA
|
| Protein Properties |
|---|
| Number of Residues
| 254 |
| Molecular Weight
| 27578.3 |
| Theoretical pI
| 8.91 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>C-X-C motif chemokine 16
MGRDLRPGSRVLLLLLLLLLVYLTQPGNGNEGSVTGSCYCGKRISSDSPPSVQFMNRLRK
HLRAYHRCLYYTRFQLLSWSVCGGNKDPWVQELMSCLDLKECGHAYSGIVAHQKHLLPTS
PPISQASEGASSDIHTPAQMLLSTLQSTQRPTLPVGSLSSDKELTRPNETTIHTAGHSLA
AGPEAGENQKQPEKNAGPTARTSATVPVLCLLAIIFILTAALSYVLCKRRRGQSPQSSPD
LPVHYIPVAPDSNT
|
| External Links |
|---|
| GenBank ID Protein
| 11139544 |
| UniProtKB/Swiss-Prot ID
| Q9H2A7 |
| UniProtKB/Swiss-Prot Entry Name
| CXL16_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AF275260 |
| GeneCard ID
| CXCL16 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |