Showing Protein Parathyroid hormone-related protein (CDBP01796)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 1 compounds
Identification
HMDB Protein ID CDBP01796
Secondary Accession Numbers Not Available
Name Parathyroid hormone-related protein
Description Not Available
Synonyms
  1. Osteostatin
  2. PLP
  3. PTH-rP
  4. PTHrP
  5. PTHrP[1-36]
  6. PTHrP[107-139]
  7. PTHrP[38-94]
  8. Parathyroid hormone-like protein
Gene Name PTHLH
Protein Type Receptor
Biological Properties
General Function Involved in hormone activity
Specific Function Osteostatin is a potent inhibitor of osteoclastic bone resorption
GO Classification
Component
extracellular region
Function
hormone activity
binding
protein binding
receptor binding
Cellular Location
  1. Nucleus
  2. Cytoplasm
  3. Secreted
Pathways
Gene Properties
Chromosome Location Chromosome:1
Locus 12p12.1-p11.2
SNPs PTHLH
Gene Sequence 
>531 bp
ATGCAGCGGAGACTGGTTCAGCAGTGGAGCGTCGCGGTGTTCCTGCTGAGCTACGCGGTG
CCCTCCTGCGGGCGCTCGGTGGAGGGTCTCAGCCGCCGCCTCAAAAGAGCTGTGTCTGAA
CATCAGCTCCTCCATGACAAGGGGAAGTCCATCCAAGATTTACGGCGACGATTCTTCCTT
CACCATCTGATCGCAGAAATCCACACAGCTGAAATCAGAGCTACCTCGGAGGTGTCCCCT
AACTCCAAGCCCTCTCCCAACACAAAGAACCACCCCGTCCGATTTGGGTCTGATGATGAG
GGCAGATACCTAACTCAGGAAACTAACAAGGTGGAGACGTACAAAGAGCAGCCGCTCAAG
ACACCTGGGAAGAAAAAGAAAGGCAAGCCCGGGAAACGCAAGGAGCAGGAAAAGAAAAAA
CGGCGAACTCGCTCTGCCTGGTTAGACTCTGGAGTGACTGGGAGTGGGCTAGAAGGGGAC
CACCTGTCTGACACCTCCACAACGTCGCTGGAGCTCGATTCACGGAGGCAT
Protein Properties
Number of Residues 177
Molecular Weight 20193.7
Theoretical pI 10.9
Pfam Domain Function
Signals
  • ["1-24"]
Transmembrane Regions
  • ["None"]
Protein Sequence 
>Parathyroid hormone-related protein
MQRRLVQQWSVAVFLLSYAVPSCGRSVEGLSRRLKRAVSEHQLLHDKGKSIQDLRRRFFL
HHLIAEIHTAEIRATSEVSPNSKPSPNTKNHPVRFGSDDEGRYLTQETNKVETYKEQPLK
TPGKKKKGKPGKRKEQEKKKRRTRSAWLDSGVTGSGLEGDHLSDTSTTSLELDSRRH
GenBank ID Protein 49456719
UniProtKB/Swiss-Prot ID P12272
UniProtKB/Swiss-Prot Entry Name PTHR_HUMAN
PDB IDs
GenBank Gene ID CR541882
GeneCard ID PTHLH
GenAtlas ID PTHLH
HGNC ID HGNC:9607
References
General References Not Available