Showing Protein Endothelin-1 (CDBP01781)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 0 compounds
Identification
HMDB Protein ID CDBP01781
Secondary Accession Numbers Not Available
Name Endothelin-1
Description Not Available
Synonyms
  1. Big endothelin-1
  2. ET-1
  3. Endothelin-1
  4. PPET1
  5. Preproendothelin-1
Gene Name EDN1
Protein Type Enzyme
Biological Properties
General Function Involved in endothelin A receptor binding
Specific Function Endothelins are endothelium-derived vasoconstrictor peptides
GO Classification
Component
extracellular region
Process
regulation of biological process
regulation of multicellular organismal process
regulation of system process
regulation of vasoconstriction
biological regulation
Cellular Location
  1. Secreted
Pathways
Gene Properties
Chromosome Location Chromosome:6
Locus 6p24.1
SNPs EDN1
Gene Sequence 
>639 bp
ATGGATTATTTGCTCATGATTTTCTCTCTGCTGTTTGTGGCTTGCCAAGGAGCTCCAGAA
ACAGCAGTCTTAGGCGCTGAGCTCAGCGCGGTGGGTGAGAACGGCGGGGAGAAACCCACT
CCCAGTCCACCCTGGCGGCTCCGCCGGTCCAAGCGCTGCTCCTGCTCGTCCCTGATGGAT
AAAGAGTGTGTCTACTTCTGCCACCTGGACATCATTTGGGTCAACACTCCCGAGCACGTT
GTTCCGTATGGACTTGGAAGCCCTAGGTCCAAGAGAGCCTTGGAGAATTTACTTCCCACA
AAGGCAACAGACCGTGAGAATAGATGCCAATGTGCTAGCCAAAAAGACAAGAAGTGCTGG
AATTTTTGCCAAGCAGGAAAAGAACTCAGGGCTGAAGACATTATGGAGAAAGACTGGAAT
AATCATAAGAAAGGAAAAGACTGTTCCAAGCTTGGGAAAAAGTGTATTTATCAGCAGTTA
GTGAGAGGAAGAAAAATCAGAAGAAGTTCAGAGGAACACCTAAGACAAACCAGGTCGGAG
ACCATGAGAAACAGCGTCAAATCATCTTTTCATGATCCCAAGCTGAAAGGCAAGCCCTCC
AGAGAGCGTTATGTGACCCACAACCGAGCACATTGGTGA
Protein Properties
Number of Residues 212
Molecular Weight 24424.9
Theoretical pI 9.92
Pfam Domain Function
Signals
  • ["1-17"]
Transmembrane Regions
  • ["None"]
Protein Sequence 
>Endothelin-1
MDYLLMIFSLLFVACQGAPETAVLGAELSAVGENGGEKPTPSPPWRLRRSKRCSCSSLMD
KECVYFCHLDIIWVNTPEHVVPYGLGSPRSKRALENLLPTKATDRENRCQCASQKDKKCW
NFCQAGKELRAEDIMEKDWNNHKKGKDCSKLGKKCIYQQLVRGRKIRRSSEEHLRQTRSE
TMRNSVKSSFHDPKLKGKPSRERYVTHNRAHW
GenBank ID Protein 37654538
UniProtKB/Swiss-Prot ID P05305
UniProtKB/Swiss-Prot Entry Name EDN1_HUMAN
PDB IDs
GenBank Gene ID AY434104
GeneCard ID EDN1
GenAtlas ID Not Available
HGNC ID Not Available
References
General References Not Available