| Identification |
|---|
| HMDB Protein ID
| CDBP01769 |
| Secondary Accession Numbers
| Not Available |
| Name
| C-reactive protein |
| Description
| Not Available |
| Synonyms
|
- C-reactive protein(1-205)
|
| Gene Name
| CRP |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in choline binding |
| Specific Function
| Displays several functions associated with host defense:it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells |
| GO Classification
|
Not Available
|
| Cellular Location
|
- Secreted
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 1q21-q23 |
| SNPs
| CRP |
| Gene Sequence
|
>675 bp
ATGGAGAAGCTGTTGTGTTTCTTGGTCTTGACCAGCCTCTCTCATGCTTTTGGCCAGACA
GACATGTCGAGGAAGGCTTTTGTGTTTCCCAAAGAGTCGGATACTTCCTATGTATCCCTC
AAAGCACCGTTAACGAAGCCTCTCAAAGCCTTCACTGTGTGCCTCCACTTCTACACGGAA
CTGTCCTCGACCCGTGGGTACAGTATTTTCTCGTATGCCACCAAGAGACAAGACAATGAG
ATTCTCATATTTTGGTCTAAGGATATAGGATACAGTTTTACAGTGGGTGGGTCTGAAATA
TTATTCGAGGTTCCTGAAGTCACAGTAGCTCCAGTACACATTTGTACAAGCTGGGAGTCC
GCCTCAGGGATCGTGGAGTTCTGGGTAGATGGGAAGCCCAGGGTGAGGAAGAGTCTGAAG
AAGGGATACACTGTGGGGGCAGAAGCAAGCATCATCTTGGGGCAGGAGCAGGATTCCTTC
GGTGGGAACTTTGAAGGAAGCCAGTCCCTGGTGGGAGACATTGGAAATGTGAACATGTGG
GACTTTGTGCTGTCACCAGATGAGATTAACACCATCTATCTTGGCGGGCCCTTCAGTCCT
AATGTCCTGAACTGGCGGGCACTGAAGTATGAAGTGCAAGGCGAAGTGTTCACCAAACCC
CAGCTGTGGCCCTGA
|
| Protein Properties |
|---|
| Number of Residues
| 224 |
| Molecular Weight
| 25038.4 |
| Theoretical pI
| 5.32 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>C-reactive protein
MEKLLCFLVLTSLSHAFGQTDMSRKAFVFPKESDTSYVSLKAPLTKPLKAFTVCLHFYTE
LSSTRGYSIFSYATKRQDNEILIFWSKDIGYSFTVGGSEILFEVPEVTVAPVHICTSWES
ASGIVEFWVDGKPRVRKSLKKGYTVGAEASIILGQEQDSFGGNFEGSQSLVGDIGNVNMW
DFVLSPDEINTIYLGGPFSPNVLNWRALKYEVQGEVFTKPQLWP
|
| External Links |
|---|
| GenBank ID Protein
| 17975775 |
| UniProtKB/Swiss-Prot ID
| P02741 |
| UniProtKB/Swiss-Prot Entry Name
| CRP_HUMAN |
| PDB IDs
|
|
| GenBank Gene ID
| AF442818 |
| GeneCard ID
| CRP |
| GenAtlas ID
| CRP |
| HGNC ID
| HGNC:2367 |
| References |
|---|
| General References
| Not Available |