Cannabis Compound Database: Showing Protein Guanine nucleotide-binding protein G(q) subunit alpha (CDBP01740)

Identification Biological properties Gene properties Protein properties External links References XML Show 4 compounds

Identification

HMDB Protein ID

CDBP01740

Secondary Accession Numbers

Not Available

Name

Guanine nucleotide-binding protein G(q) subunit alpha

Description

Not Available

Synonyms

Guanine nucleotide-binding protein alpha-q

Gene Name

GNAQ

Protein Type

Enzyme

Biological Properties

General Function

Involved in signal transducer activity

Specific Function

Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems

GO Classification

Function
gtp binding
molecular transducer activity
signal transducer activity
purine nucleotide binding
binding
nucleotide binding
guanyl nucleotide binding
guanyl ribonucleotide binding
Process
g-protein coupled receptor protein signaling pathway
metabolic process
macromolecule metabolic process
protein amino acid adp-ribosylation
biological regulation
regulation of biological process
post-translational protein modification
regulation of cellular process
signal transduction
macromolecule modification
protein modification process
signaling
signaling pathway
cell surface receptor linked signaling pathway

Cellular Location

Not Available

Pathways

Name	SMPDB/Pathwhiz	KEGG
Activation of PKC through G protein coupled receptor		Not Available
Chlorphenamine H1-Antihistamine Action		Not Available
Pheniramine H1-Antihistamine Action		Not Available
Dexchlorpheniramine H1-Antihistamine Action		Not Available
Brompheniramine H1-Antihistamine Action		Not Available

Gene Properties

Chromosome Location

Chromosome:9

Locus

9q21

SNPs

GNAQ

Gene Sequence

>1080 bp
ATGACTCTGGAGTCCATCATGGCGTGCTGCCTGAGCGAGGAGGCCAAGGAAGCCCGGCGG
ATCAACGACGAGATCGAGCGGCACGTCCGCAGGGACAAGCGGGACGCCCGCCGGGAGCTC
AAGCTGCTGCTGCTCGGGACAGGAGAGAGTGGCAAGAGTACGTTTATCAAGCAGATGAGA
ATCATCCATGGGTCAGGATACTCTGATGAAGATAAAAGGGGCTTCACCAAGCTGGTGTAT
CAGAACATCTTCACGGCCATGCAGGCCATGATCAGAGCCATGGACACACTCAAGATCCCA
TACAAGTATGAGCACAATAAGGCTCATGCACAATTAGTTCGAGAAGTTGATGTGGAGAAG
GTGTCTGCTTTTGAGAATCCATATGTAGATGCAATAAAGAGTTTATGGAATGATCCTGGA
ATCCAGGAATGCTATGATAGACGACGAGAATATCAATTATCTGACTCTACCAAATACTAT
CTTAATGACTTGGACCGCGTAGCTGACCCTGCCTACCTGCCTACGCAACAAGATGTGCTT
AGAGTTCGAGTCCCCACCACAGGGATCATCGAATACCCCTTTGACTTACAAAGTGTCATT
TTCAGAATGGTCGATGTAGGGGGCCAAAGGTCAGAGAGAAGAAAATGGATACACTGCTTT
GAAAATGTCACCTCTATCATGTTTCTAGTAGCGCTTAGTGAATATGATCAAGTTCTCGTG
GAGTCAGACAATGAGAACCGAATGGAGGAAAGCAAGGCTCTCTTTAGAACAATTATCACA
TACCCCTGGTTCCAGAACTCCTCGGTTATTCTGTTCTTAAACAAGAAAGATCTTCTAGAG
GAGAAAATCATGTATTCCCATCTAGTCGACTACTTCCCAGAATATGATGGACCCCAGAGA
GATGCCCAGGCAGCCCGAGAATTCATTCTGAAGATGTTCGTGGACCTGAACCCAGACAGT
GACAAAATTATCTACTCCCACTTCACGTGCGCCACAGACACCGAGAATATCCGCTTTGTC
TTTGCTGCCGTCAAGGACACCATCCTCCAGTTGAACCTGAAGGAGTACAATCTGGTCTAA

Protein Properties

Number of Residues

359

Molecular Weight

42141.7

Theoretical pI

5.37

Pfam Domain Function

G-alpha (PF00503 )

Signals

["None"]

Transmembrane Regions

["None"]

Protein Sequence

>Guanine nucleotide-binding protein G(q) subunit alpha
MTLESIMACCLSEEAKEARRINDEIERQLRRDKRDARRELKLLLLGTGESGKSTFIKQMR
IIHGSGYSDEDKRGFTKLVYQNIFTAMQAMIRAMDTLKIPYKYEHNKAHAQLVREVDVEK
VSAFENPYVDAIKSLWNDPGIQECYDRRREYQLSDSTKYYLNDLDRVADPAYLPTQQDVL
RVRVPTTGIIEYPFDLQSVIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLV
ESDNENRMEESKALFRTIITYPWFQNSSVILFLNKKDLLEEKIMYSHLVDYFPEYDGPQR
DAQAAREFILKMFVDLNPDSDKIIYSHFTCATDTENIRFVFAAVKDTILQLNLKEYNLV

External Links

GenBank ID Protein

1181671

UniProtKB/Swiss-Prot ID

P50148

UniProtKB/Swiss-Prot Entry Name

GNAQ_HUMAN

PDB IDs

Not Available

GenBank Gene ID

U40038

GeneCard ID