Showing Protein Growth arrest-specific protein 6 (CDBP01731)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 1 compounds
Identification
HMDB Protein ID CDBP01731
Secondary Accession Numbers Not Available
Name Growth arrest-specific protein 6
Description Not Available
Synonyms
  1. AXL receptor tyrosine kinase ligand
  2. GAS-6
Gene Name GAS6
Protein Type Metal Binding
Biological Properties
General Function Involved in calcium ion binding
Specific Function Ligand for tyrosine-protein kinase receptors AXL, TYRO3 and MER whose signaling is implicated in cell growth and survival, cell adhesion and cell migration. Plays a role in thrombosis by amplifying platelet aggregation and secretion in response to known agonists
GO Classification
Component
extracellular region
Function
calcium ion binding
ion binding
cation binding
metal ion binding
binding
Cellular Location
  1. Secreted
Pathways
Gene Properties
Chromosome Location Chromosome:1
Locus 13q34
SNPs GAS6
Gene Sequence Not Available
Protein Properties
Number of Residues 721
Molecular Weight 79675.8
Theoretical pI 6.15
Pfam Domain Function
Signals
  • ["1-30"]
Transmembrane Regions
  • ["None"]
Protein Sequence 
>Growth arrest-specific protein 6
MAPSLSPGPAALRRAPQLLLLLLAAECALAALLPAREATQFLRPRQRRAFQVFEEAKQGH
LERECVEELCSREEAREVFENDPETDYFYPRYLDCINKYGSPYTKNSGFATCVQNLPDQC
TPNPCDRKGTQACQDLMGNFFCLCKAGWGGRLCDKDVNECSQENGGCLQICHNKPGSFHC
SCHSGFELSSDGRTCQDIDECADSEACGEARCKNLPGSYSCLCDEGFAYSSQEKACRDVD
ECLQGRCEQVCVNSPGSYTCHCDGRGGLKLSQDMDTCELEAGWPCPRHRRDGSPAARPGR
GAQGSRSEGHIPDRRGPRPWQDILPCVPFSVAKSVKSLYLGRMFSGTPVIRLRFKRLQPT
RLVAEFDFRTFDPEGILLFAGGHQDSTWIVLALRAGRLELQLRYNGVGRVTSSGPVINHG
MWQTISVEELARNLVIKVNRDAVMKIAVAGDLFQPERGLYHLNLTVGGIPFHEKDLVQPI
NPRLDGCMRSWNWLNGEDTTIQETVKVNTRMQCFSVTERGSFYPGSGFAFYSLDYMRTPL
DVGTESTWEVEVVAHIRPAADTGVLFALWAPDLRAVPLSVALVDYHSTKKLKKQLVVLAV
EHTALALMEIKVCDGQEHVVTVSLRDGEATLEVDGTRGQSEVSAAQLQERLAVLERHLRS
PVLTFAGGLPDVPVTSAPVTAFYRGCMTLEVNRRLLDLDEAAYKHSDITAHSCPPVEPAA
A
GenBank ID Protein 221316738
UniProtKB/Swiss-Prot ID Q14393
UniProtKB/Swiss-Prot Entry Name GAS6_HUMAN
PDB IDs Not Available
GenBank Gene ID Not Available
GeneCard ID GAS6
GenAtlas ID GAS6
HGNC ID HGNC:4168
References
General References Not Available