| Identification |
|---|
| HMDB Protein ID
| CDBP01727 |
| Secondary Accession Numbers
| Not Available |
| Name
| Osteocalcin |
| Description
| Not Available |
| Synonyms
|
- BGP
- Bone Gla protein
- Gamma-carboxyglutamic acid-containing protein
|
| Gene Name
| BGLAP |
| Protein Type
| Metal Binding |
| Biological Properties |
|---|
| General Function
| Involved in regulation of bone mineralization |
| Specific Function
| Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium |
| GO Classification
|
| Component |
| extracellular region |
| Function |
| ion binding |
| cation binding |
| metal ion binding |
| binding |
| calcium ion binding |
| Process |
| biological regulation |
| regulation of biological process |
| regulation of ossification |
| regulation of bone mineralization |
| regulation of multicellular organismal process |
|
| Cellular Location
|
- Secreted
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 1q25-q31 |
| SNPs
| BGLAP |
| Gene Sequence
|
>303 bp
ATGAGAGCCCTCACACTCCTCGCCCTATTGGCCCTGGCCGCACTTTGCATCGCTGGCCAG
GCAGGTGCGAAGCCCAGCGGTGCAGAGTCCAGCAAAGGTGCAGCCTTTGTGTCCAAGCAG
GAGGGCAGCGAGGTAGTGAAGAGACCCAGGCGCTACCTGTATCAATGGCTGGGAGCCCCA
GTCCCCTACCCGGATCCCCTGGAGCCCAGGAGGGAGGTGTGTGAGCTCAATCCGGACTGT
GACGAGTTGGCTGACCACATCGGCTTTCAGGAGGCCTATCGGCGCTTCTACGGCCCGGTC
TAG
|
| Protein Properties |
|---|
| Number of Residues
| 100 |
| Molecular Weight
| 10962.4 |
| Theoretical pI
| 7.18 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Osteocalcin
MRALTLLALLALAALCIAGQAGAKPSGAESSKGAAFVSKQEGSEVVKRPRRYLYQWLGAP
VPYPDPLEPRREVCELNPDCDELADHIGFQEAYRRFYGPV
|
| External Links |
|---|
| GenBank ID Protein
| 36093 |
| UniProtKB/Swiss-Prot ID
| P02818 |
| UniProtKB/Swiss-Prot Entry Name
| OSTCN_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| X53698 |
| GeneCard ID
| BGLAP |
| GenAtlas ID
| BGLAP |
| HGNC ID
| HGNC:1043 |
| References |
|---|
| General References
| Not Available |