Showing Protein Apolipoprotein C-III precursor (CDBP01718)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 650 compounds
Identification
HMDB Protein ID CDBP01718
Secondary Accession Numbers Not Available
Name Apolipoprotein C-III precursor
Description Not Available
Synonyms
  1. Apo-CIII
  2. ApoC-III
Gene Name APOC3
Protein Type Transporter
Biological Properties
General Function Not Available
Specific Function Inhibits lipoprotein lipase and hepatic lipase and decreases the uptake of lymph chylomicrons by hepatic cells. This suggests that it delays the catabolism of triglyceride-rich particles
GO Classification
Component
extracellular region
Function
binding
lipid binding
Process
lipoprotein metabolism
transport
physiological process
metabolism
macromolecule metabolism
protein metabolism
cellular protein metabolism
cellular physiological process
lipid transport
Cellular Location
  1. Secreted
Pathways
Gene Properties
Chromosome Location Chromosome:11
Locus 11q23.1-q23.2
SNPs APOC3
Gene Sequence 
>300 bp
ATGCAGCCCCGGGTACTCCTTGTTGTTGCCCTCCTGGCGCTCCTGGCCTCTGCCCGAGCT
TCAGAGGCCGAGGATGCCTCCCTTCTCAGCTTCATGCAGGGCTACATGAAGCACGCCACC
AAGACCGCCAAGGATGCACTGAGCAGCGTGCAGGAGTCCCAGGTGGCCCAGCAGGCCAGG
GGCTGGGTGACCGATGGCTTCAGTTCCCTGAAAGACTACTGGAGCACCGTTAAGGACAAG
TTCTCTGAGTTCTGGGATTTGGACCCTGAGGTCAGACCAACTTCAGCCGTGGCTGCCTGA
Protein Properties
Number of Residues 99
Molecular Weight 10852.0
Theoretical pI 5.04
Pfam Domain Function
Signals
  • ["1-20"]
Transmembrane Regions Not Available
Protein Sequence 
>Apolipoprotein C-III precursor
MQPRVLLVVALLALLASARASEAEDASLLSFMQGYMKHATKTAKDALSSVQESQVAQQAR
GWVTDGFSSLKDYWSTVKDKFSEFWDLDPEVRPTSAVAA
GenBank ID Protein 178768
UniProtKB/Swiss-Prot ID P02656
UniProtKB/Swiss-Prot Entry Name APOC3_HUMAN
PDB IDs Not Available
GenBank Gene ID J00098
GeneCard ID APOC3
GenAtlas ID APOC3
HGNC ID HGNC:610
References
General References Not Available