Cannabis Compound Database: Showing Protein GTPase HRas (CDBP01703)

Identification Biological properties Gene properties Protein properties External links References XML Show 3 compounds

Identification

HMDB Protein ID

CDBP01703

Secondary Accession Numbers

Not Available

Name

GTPase HRas

Description

Not Available

Synonyms

GTPase HRas, N-terminally processed
H-Ras-1
Ha-Ras
Transforming protein p21
c-H-ras
p21ras

Gene Name

HRAS

Protein Type

Enzyme

Biological Properties

General Function

Involved in GTP binding

Specific Function

Ras proteins bind GDP/GTP and possess intrinsic GTPase activity

GO Classification

Component
membrane
cell part
intracellular
Function
nucleotide binding
catalytic activity
hydrolase activity
guanyl nucleotide binding
guanyl ribonucleotide binding
gtp binding
gtpase activity
nucleoside-triphosphatase activity
hydrolase activity, acting on acid anhydrides
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
pyrophosphatase activity
purine nucleotide binding
binding
Process
small gtpase mediated signal transduction
biological regulation
regulation of biological process
regulation of cellular process
signal transduction
intracellular signal transduction

Cellular Location

Cell membrane
Lipid-anchor
Lipid-anchor
Golgi apparatus membrane
Cytoplasmic side

Pathways

Name	SMPDB/Pathwhiz	KEGG
Intracellular Signalling Through Adenosine Receptor A2a and Adenosine		Not Available
Intracellular Signalling Through Adenosine Receptor A2b and Adenosine		Not Available
Fc Epsilon Receptor I Signaling in Mast Cells		Not Available
Insulin Signalling		Not Available

Gene Properties

Chromosome Location

Chromosome:1

Locus

11p15.5

SNPs

HRAS

Gene Sequence

>570 bp
ATGACGGAATATAAGCTGGTGGTGGTGGGCGCCGGCGGTGTGGGCAAGAGTGCGCTGACC
ATCCAGCTGATCCAGAACCATTTTGTGGACGAATACGACCCCACTATAGAGGATTCCTAC
CGGAAGCAGGTGGTCATTGATGGGGAGACGTGCCTGTTGGACATCCTGGATACCGCCGGC
CAGGAGGAGTACAGCGCCATGCGGGACCAGTACATGCGCACCGGGGAGGGCTTCCTGTGT
GTGTTTGCCATCAACAACACCAAGTCTTTTGAGGACATCCACCAGTACAGGGAGCAGATC
AAACGGGTGAAGGACTCGGATGACGTGCCCATGGTGCTGGTGGGGAACAAGTGTGACCTG
GCTGCACGCACTGTGGAATCTCGGCAGGCTCAGGACCTCGCCCGAAGCTACGGCATCCCC
TACATCGAGACCTCGGCCAAGACCCGGCAGGGAGTGGAGGATGCCTTCTACACGTTGGTG
CGTGAGATCCGGCAGCACAAGCTGCGGAAGCTGAACCCTCCTGATGAGAGTGGCCCCGGC
TGCATGAGCTGCAAGTGTGTGCTCTCCTGA

Protein Properties

Number of Residues

189

Molecular Weight

21298.0

Theoretical pI

4.94

Pfam Domain Function

Ras (PF00071 )

Signals

["None"]

Transmembrane Regions

["None"]

Protein Sequence

>GTPase HRas
MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAG
QEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDL
AARTVESRQAQDLARSYGIPYIETSAKTRQGVEDAFYTLVREIRQHKLRKLNPPDESGPG
CMSCKCVLS

External Links

GenBank ID Protein

20147725

UniProtKB/Swiss-Prot ID

P01112

UniProtKB/Swiss-Prot Entry Name

RASH_HUMAN

PDB IDs