| Identification |
|---|
| HMDB Protein ID
| CDBP01636 |
| Secondary Accession Numbers
| Not Available |
| Name
| Transthyretin |
| Description
| Not Available |
| Synonyms
|
- ATTR
- Prealbumin
- TBPA
|
| Gene Name
| TTR |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in hormone activity |
| Specific Function
| Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain |
| GO Classification
|
Not Available
|
| Cellular Location
|
- Cytoplasm
- Secreted
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 18q12.1 |
| SNPs
| TTR |
| Gene Sequence
|
>444 bp
ATGGCTTCTCATCGTCTGCTCCTCCTCTGCCTTGCTGGACTGGTATTTGTGTCTGAGGCT
GGCCCTACGGGCACCGGTGAATCCAAGTGTCCTCTGATGGTCAAAGTTCTAGATGCTGTC
CGAGGCAGTCCTGCCATCAATGTGGCCGTGCATGTGTTCAGAAAGGCTGCTGATGACACC
TGGGAGCCATTTGCCTCTGGGAAAACCAGTGAGTCTGGAGAGCTGCATGGGCTCACAACT
GAGGAGGAATTTGTAGAAGGGATATACAAAGTGGAAATAGACACCAAATCTTACTGGAAG
GCACTTGGCATCTCCCCATTCCATGAGCATGCAGAGGTGGTATTCACAGCCAACGACTCC
GGCCCCCGCCGCTACACCATTGCCGCCCTGCTGAGCCCCTACTCCTATTCCACCACGGCT
GTCGTCACCAATCCCAAGGAATGA
|
| Protein Properties |
|---|
| Number of Residues
| 147 |
| Molecular Weight
| 15886.9 |
| Theoretical pI
| 5.58 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Transthyretin
MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDT
WEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDS
GPRRYTIAALLSPYSYSTTAVVTNPKE
|
| External Links |
|---|
| GenBank ID Protein
| 189582 |
| UniProtKB/Swiss-Prot ID
| P02766 |
| UniProtKB/Swiss-Prot Entry Name
| TTHY_HUMAN |
| PDB IDs
|
|
| GenBank Gene ID
| K02091 |
| GeneCard ID
| TTR |
| GenAtlas ID
| TTR |
| HGNC ID
| HGNC:12405 |
| References |
|---|
| General References
| Not Available |