| Identification |
|---|
| HMDB Protein ID
| CDBP01635 |
| Secondary Accession Numbers
| Not Available |
| Name
| Oxytocin-neurophysin 1 |
| Description
| Not Available |
| Synonyms
|
- Neurophysin 1
- OT-NPI
- Ocytocin
- Oxytocin
|
| Gene Name
| OXT |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in neurohypophyseal hormone activity |
| Specific Function
| Oxytocin causes contraction of the smooth muscle of the uterus and of the mammary gland |
| GO Classification
|
| Component |
| extracellular region |
| Function |
| hormone activity |
| binding |
| protein binding |
| receptor binding |
| neuropeptide hormone activity |
| neurohypophyseal hormone activity |
|
| Cellular Location
|
- Secreted
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:2 |
| Locus
| 20p13 |
| SNPs
| OXT |
| Gene Sequence
|
>378 bp
ATGGCCGGCCCCAGCCTCGCTTGCTGTCTGCTCGGCCTCCTGGCGCTGACCTCCGCCTGC
TACATCCAGAACTGCCCCCTGGGAGGCAAGAGGGCCGCGCCGGACCTCGACGTGCGCAAG
TGCCTCCCCTGCGGCCCCGGGGGCAAAGGCCGCTGCTTCGGGCCCAATATCTGCTGCGCG
GAAGAGCTGGGCTGCTTCGTGGGCACCGCCGAAGCGCTGCGCTGCCAGGAGGAGAACTAC
CTGCCGTCGCCCTGCCAGTCCGGCCAGAAGGCGTGCGGGAGCGGGGGCCGCTGCGCGGTC
TTGGGCCTCTGCTGCAGCCCGGACGGCTGCCACGCCGACCCTGCCTGCGACGCGGAAGCC
ACCTTCTCCCAGCGCTGA
|
| Protein Properties |
|---|
| Number of Residues
| 125 |
| Molecular Weight
| 12721.5 |
| Theoretical pI
| 5.78 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Oxytocin-neurophysin 1
MAGPSLACCLLGLLALTSACYIQNCPLGGKRAAPDLDVRKCLPCGPGGKGRCFGPNICCA
EELGCFVGTAEALRCQEENYLPSPCQSGQKACGSGGRCAVLGLCCSPDGCHADPACDAEA
TFSQR
|
| External Links |
|---|
| GenBank ID Protein
| 10334459 |
| UniProtKB/Swiss-Prot ID
| P01178 |
| UniProtKB/Swiss-Prot Entry Name
| NEU1_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AL160414 |
| GeneCard ID
| OXT |
| GenAtlas ID
| OXT |
| HGNC ID
| HGNC:8528 |
| References |
|---|
| General References
| Not Available |