| Identification |
|---|
| HMDB Protein ID
| CDBP01607 |
| Secondary Accession Numbers
| Not Available |
| Name
| Rho GDP-dissociation inhibitor 2 |
| Description
| Not Available |
| Synonyms
|
- Ly-GDI
- Rho GDI 2
- Rho-GDI beta
|
| Gene Name
| ARHGDIB |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in GTPase activator activity |
| Specific Function
| Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them |
| GO Classification
|
| Component |
| intracellular part |
| cytoplasm |
| cell part |
| Function |
| small gtpase regulator activity |
| enzyme regulator activity |
| gdp-dissociation inhibitor activity |
| rho gdp-dissociation inhibitor activity |
| nucleoside-triphosphatase regulator activity |
| gtpase regulator activity |
|
| Cellular Location
|
- Cytoplasm
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 12p12.3 |
| SNPs
| ARHGDIB |
| Gene Sequence
|
>606 bp
ATGACTGAAAAAGCCCCAGAGCCACATGTGGAGGAGGATGACGATGATGAGCTGGACAGC
AAGCTCAATTATAAGCCTCCACCACAGAAGTCCCTGAAAGAGCTGCAGGAAATGGACAAA
GATGATGAGAGTCTAATTAAGTACAAGAAAACGCTGCTGGGAGATGGTCCTGTGGTGACA
GATCCGAAAGCCCCCAATGTCGTTGTCACCCGGCTCACCCTGGTTTGTGAGAGTGCCCCG
GGACCAATCACCATGGACCTTACTGGAGATCTGGAAGCCCTCAAAAAGGAAACCATTGTG
TTAAAGGAAGGTTCTGAATATAGAGTCAAAATTCACTTCAAAGTGAACAGGGATATTGTG
TCAGGCCTGAAATACGTTCAGCACACCTACAGGACTGGGGTGAAAGTGGATAAAGCAACA
TTTATGGTTGGCAGCTATGGACCTCGGCCTGAGGAGTATGAGTTCCTCACTCCAGTTGAG
GAGGCTCCCAAGGGCATGCTGGCGCGAGGCACGTACCACAACAAGTCCTTCTTCACCGAC
GATGACAAGCAAGACCACCTCAGCTGGGAGTGGAACCTGTCGATTAAGAAGGAGTGGACA
GAATAA
|
| Protein Properties |
|---|
| Number of Residues
| 201 |
| Molecular Weight
| 22987.9 |
| Theoretical pI
| 4.84 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Rho GDP-dissociation inhibitor 2
MTEKAPEPHVEEDDDDELDSKLNYKPPPQKSLKELQEMDKDDESLIKYKKTLLGDGPVVT
DPKAPNVVVTRLTLVCESAPGPITMDLTGDLEALKKETIVLKEGSEYRVKIHFKVNRDIV
SGLKYVQHTYRTGVKVDKATFMVGSYGPRPEEYEFLTPVEEAPKGMLARGTYHNKSFFTD
DDKQDHLSWEWNLSIKKEWTE
|
| External Links |
|---|
| GenBank ID Protein
| 197692331 |
| UniProtKB/Swiss-Prot ID
| P52566 |
| UniProtKB/Swiss-Prot Entry Name
| GDIR2_HUMAN |
| PDB IDs
|
|
| GenBank Gene ID
| AB451315 |
| GeneCard ID
| ARHGDIB |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |