Showing Protein GTP-binding nuclear protein Ran (CDBP01593)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 1 compounds
Identification
HMDB Protein ID CDBP01593
Secondary Accession Numbers Not Available
Name GTP-binding nuclear protein Ran
Description Not Available
Synonyms
  1. Androgen receptor-associated protein 24
  2. GTPase Ran
  3. Ras-like protein TC4
  4. Ras-related nuclear protein
Gene Name RAN
Protein Type Enzyme
Biological Properties
General Function Involved in GTPase activity
Specific Function Enhances AR-mediated transactivation. Transactivation decreases as the poly-Gln length within AR increases
GO Classification
Function
binding
nucleotide binding
catalytic activity
hydrolase activity
guanyl nucleotide binding
guanyl ribonucleotide binding
gtp binding
protein binding
gtpase activity
nucleoside-triphosphatase activity
hydrolase activity, acting on acid anhydrides
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
pyrophosphatase activity
purine nucleotide binding
Process
biological regulation
regulation of biological process
nuclear transport
nucleocytoplasmic transport
regulation of cellular process
signal transduction
intracellular transport
intracellular protein transport
establishment of localization
transport
protein transport
Cellular Location
  1. Nucleus
  2. Cytoplasm
  3. Melanosome
Pathways
Gene Properties
Chromosome Location Chromosome:1
Locus 12q24.3
SNPs RAN
Gene Sequence 
>651 bp
ATGGCTGCGCAGGGAGAGCCCCAGGTCCAGTTCAAACTTGTATTGGTTGGTGATGGTGGT
ACTGGAAAAACGACCTTCGTGAAACGTCATTTGACTGGTGAATTTGAGAAGAAGTATGTA
GCCACCTTGGGTGTTGAGGTTCATCCCCTAGTGTTCCACACCAACAGAGGACCTATTAAG
TTCAATGTATGGGACACAGCCGGCCAGGAGAAATTCGGTGGACTGAGAGATGGCTATTAT
ATCCAAGCCCAGTGTGCCATCATAATGTTTGATGTAACATCGAGAGTTACTTACAAGAAT
GTGCCTAACTGGCATAGAGATCTGGTACGAGTGTGTGAAAACATCCCCATTGTGTTGTGT
GGCAACAAAGTGGATATTAAGGACAGGAAAGTGAAGGCGAAATCCATTGTCTTCCACCGA
AAGAAGAATCTTCAGTACTACGACATTTCTGCCAAAAGTAACTACAACTTTGAAAAGCCC
TTCCTCTGGCTTGCTAGGAAGCTCATTGGAGACCCTAACTTGGAATTTGTTGCCATGCCT
GCTCTCGCCCCACCAGAAGTTGTCATGGACCCAGCTTTGGCAGCACAGTATGAGCACGAC
TTAGAGGTTGCTCAGACAACTGCTCTCCCGGATGAGGATGATGACCTGTGA
Protein Properties
Number of Residues 216
Molecular Weight 24423.0
Theoretical pI 7.59
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["None"]
Protein Sequence 
>GTP-binding nuclear protein Ran
MAAQGEPQVQFKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIK
FNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPIVLC
GNKVDIKDRKVKAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLIGDPNLEFVAMP
ALAPPEVVMDPALAAQYEHDLEVAQTTALPDEDDDL
GenBank ID Protein Not Available
UniProtKB/Swiss-Prot ID P62826
UniProtKB/Swiss-Prot Entry Name RAN_HUMAN
PDB IDs
GenBank Gene ID M31469
GeneCard ID RAN
GenAtlas ID RAN
HGNC ID HGNC:9846
References
General References Not Available