| Identification |
|---|
| HMDB Protein ID
| CDBP01589 |
| Secondary Accession Numbers
| Not Available |
| Name
| Cytochrome c-type heme lyase |
| Description
| Not Available |
| Synonyms
|
- CCHL
- Holocytochrome c-type synthase
|
| Gene Name
| HCCS |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in holocytochrome-c synthase activity |
| Specific Function
| Links covalently the heme group to the apoprotein of cytochrome c (By similarity).
|
| GO Classification
|
| Biological Process |
| organ morphogenesis |
| oxidation-reduction process |
| Cellular Component |
| mitochondrial inner membrane |
| Component |
| mitochondrion |
| organelle |
| membrane-bounded organelle |
| intracellular membrane-bounded organelle |
| Function |
| carbon-sulfur lyase activity |
| catalytic activity |
| lyase activity |
| holocytochrome-c synthase activity |
| Molecular Function |
| holocytochrome-c synthase activity |
| metal ion binding |
|
| Cellular Location
|
- Mitochondrion inner membrane (Potential)
|
| Pathways
|
| Name | SMPDB/Pathwhiz | KEGG | | Porphyrin and chlorophyll metabolism | Not Available |  |
|
| Gene Properties |
|---|
| Chromosome Location
| X |
| Locus
| Xp22.3 |
| SNPs
| HCCS |
| Gene Sequence
|
>807 bp
ATGGGTTTGTCTCCATCTGCTCCTGCTGTTGCAGTTCAGGCCTCAAATGCTTCAGCGTCC
CCACCTTCAGGATGCCCGATGCATGAAGGGAAAATGAAAGGCTGTCCAGTGAATACAGAG
CCATCTGGCCCAACCTGTGAGAAGAAAACATACTCTGTGCCTGCCCACCAGGAACGCGCC
TATGAGTACGTGGAGTGTCCCATTAGGGGCACTGCGGCTGAGAATAAGGAGAACCTAGAT
CCTTCAAATCTGATGCCACCACCAAATCAAACACCAGCTCCAGATCAGCCATTTGCATTG
TCTACTGTCAGAGAAGAGTCATCCATTCCGAGAGCAGATTCAGAGAAAAAGTGGGTTTAC
CCTTCTGAGCAGATGTTCTGGAATGCAATGTTAAAGAAAGGGTGGAAGTGGAAGGATGAG
GATATCAGTCAGAAGGATATGTATAATATCATTAGAATTCACAATCAGAATAACGAGCAG
GCTTGGAAGGAGATTTTGAAGTGGGAAGCCCTTCATGCTGCAGAGTGTCCTTGTGGTCCA
TCATTGATCCGGTTTGGAGGGAAAGCAAAAGAGTATTCACCAAGGGCACGAATTCGTTCC
TGGATGGGGTATGAGTTGCCTTTTGATAGGCACGATTGGATCATAAACCGTTGCGGGACA
GAAGTTAGATATGTGATTGATTATTATGATGGTGGTGAAGTCAACAAGGACTACCAGTTC
ACCATCCTGGACGTCCGTCCTGCCTTAGATTCACTTTCGGCAGTATGGGACAGAATGAAA
GTCGCTTGGTGGCGTTGGACCTCGTAA
|
| Protein Properties |
|---|
| Number of Residues
| 268 |
| Molecular Weight
| 30601.335 |
| Theoretical pI
| 6.682 |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Cytochrome c-type heme lyase
MGLSPSAPAVAVQASNASASPPSGCPMHEGKMKGCPVNTEPSGPTCEKKTYSVPAHQERA
YEYVECPIRGTAAENKENLDPSNLMPPPNQTPAPDQPFALSTVREESSIPRADSEKKWVY
PSEQMFWNAMLKKGWKWKDEDISQKDMYNIIRIHNQNNEQAWKEILKWEALHAAECPCGP
SLIRFGGKAKEYSPRARIRSWMGYELPFDRHDWIINRCGTEVRYVIDYYDGGEVNKDYQF
TILDVRPALDSLSAVWDRMKVAWWRWTS
|
| External Links |
|---|
| GenBank ID Protein
| 3582744 |
| UniProtKB/Swiss-Prot ID
| P53701 |
| UniProtKB/Swiss-Prot Entry Name
| CCHL_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AF053015 |
| GeneCard ID
| HCCS |
| GenAtlas ID
| HCCS |
| HGNC ID
| HGNC:4837 |
| References |
|---|
| General References
| Not Available |