| Identification |
|---|
| HMDB Protein ID
| CDBP01575 |
| Secondary Accession Numbers
| Not Available |
| Name
| Ubiquinone biosynthesis protein COQ7 homolog |
| Description
| Not Available |
| Synonyms
|
- Coenzyme Q biosynthesis protein 7 homolog
- Timing protein clk-1 homolog
|
| Gene Name
| COQ7 |
| Protein Type
| Metal Binding |
| Biological Properties |
|---|
| General Function
| Involved in oxidoreductase activity |
| Specific Function
| Involved in lifespan determination in ubiquinone-independent manner. Involved in ubiquinone biosynthesis. Potential central metabolic regulator (By similarity).
|
| GO Classification
|
| Biological Process |
| response to drug |
| cellular response to oxidative stress |
| ubiquinone biosynthetic process |
| age-dependent response to oxidative stress |
| determination of adult lifespan |
| mitochondrial ATP synthesis coupled electron transport |
| mitochondrion morphogenesis |
| neural tube formation |
| neurogenesis |
| in utero embryonic development |
| Cellular Component |
| nucleus |
| mitochondrial inner membrane |
| Function |
| ion binding |
| cation binding |
| metal ion binding |
| binding |
| catalytic activity |
| transition metal ion binding |
| oxidoreductase activity |
| Molecular Function |
| transition metal ion binding |
| oxidoreductase activity |
| Process |
| oxidoreduction coenzyme metabolic process |
| ubiquinone metabolic process |
| ubiquinone biosynthetic process |
| oxidation reduction |
| cofactor metabolic process |
| coenzyme metabolic process |
| protein metabolic process |
| metabolic process |
| macromolecule metabolic process |
| cellular metabolic process |
|
| Cellular Location
|
- Peripheral membrane protein
- Mitochondrion inner membrane
- Matrix side
|
| Pathways
|
| Name | SMPDB/Pathwhiz | KEGG | | Ubiquinone and other terpenoid-quinone biosynthesis | Not Available |  | | Ubiquinone Biosynthesis |    | |
|
| Gene Properties |
|---|
| Chromosome Location
| Not Available |
| Locus
| Not Available |
| SNPs
| COQ7 |
| Gene Sequence
|
>654 bp
ATGAGTTGCGCCGGGGCGGCGGCGGCTCCCCGCCTTTGGCGGCTGCGCCCGGGGGCCCGG
CGGTCCCTCTCAGCTTATGGAAGAAGAACCAGTGTCAGATTTCGCAGTTCAGGAATGACT
TTAGACAATATCAGTCGGGCAGCTGTGGATCGAATAATCCGGGTGGATCATGCAGGCGAA
TATGGAGCAAACCGCATCTATGCCGGGCAGATGGCTGTCCTGGGTCGGACCAGCGTCGGG
CCAGTCATTCAGAAAATGTGGGATCAAGAAAAGGACCATTTGAAAAAGTTCAATGAGTTG
ATGGTTACGTTCAGGGTCCGGCCAACAGTTCTGATGCCCTTGTGGAACGTGCTGGGGTTT
GCACTGGGGGCGGGGACCGCCTTGCTCGGGAAGGAAGGTGCCATGGCCTGCACCGTGGCG
GTGGAAGAGAGCATAGCACATCACTACAACAACCAGATCAGGACGCTGATGGAGGAGGAC
CCTGAAAAATACGAGGAACTTCTTCAGCTGATAAAGAAATTTCGGGATGAAGAGCTTGAG
CACCATGACATAGGCCTCGACCATGATGCAGAATTGGCTCCAGCCTATGCCGTCCTGAAG
AGCATTATCCAGGCCGGATGCAGAGTGGCGATATATTTATCAGAAAGATTATAA
|
| Protein Properties |
|---|
| Number of Residues
| 217 |
| Molecular Weight
| Not Available |
| Theoretical pI
| Not Available |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Ubiquinone biosynthesis protein COQ7 homolog
MSCAGAAAAPRLWRLRPGARRSLSAYGRRTSVRFRSSGMTLDNISRAAVDRIIRVDHAGE
YGANRIYAGQMAVLGRTSVGPVIQKMWDQEKDHLKKFNELMVMFRVRPTVLMPLWNVLGF
ALGAGTALLGKEGAMACTVAVEESIAHHYNNQIRTLMEEDPEKYEELLQLIKKFRDEELE
HHDIGLDHDAELAPAYAVLKSIIQAGCRVAIYLSERL
|
| External Links |
|---|
| GenBank ID Protein
| 25453484 |
| UniProtKB/Swiss-Prot ID
| Q99807 |
| UniProtKB/Swiss-Prot Entry Name
| COQ7_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_016138.4 |
| GeneCard ID
| COQ7 |
| GenAtlas ID
| COQ7 |
| HGNC ID
| HGNC:2244 |
| References |
|---|
| General References
| Not Available |