| Identification |
|---|
| HMDB Protein ID
| CDBP01509 |
| Secondary Accession Numbers
| Not Available |
| Name
| Hemopexin |
| Description
| Not Available |
| Synonyms
|
- Beta-1B-glycoprotein
|
| Gene Name
| HPX |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in heme transporter activity |
| Specific Function
| Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation |
| GO Classification
|
Not Available
|
| Cellular Location
|
- Secreted
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 11p15.5-p15.4 |
| SNPs
| HPX |
| Gene Sequence
|
>1389 bp
ATGGCTAGGGTACTGGGAGCACCCGTTGCACTGGGGTTGTGGAGCCTATGCTGGTCTCTG
GCCATTGCCACCCCTCTTCCTCCGACTAGTGCCCATGGGAATGTTGCTGAAGGCGAGACC
AAGCCAGACCCAGACGTGACTGAACGCTGCTCAGATGGCTGGAGCTTTGATGCTACCACC
CTGGATGACAATGGAACCATGCTGTTTTTTAAAGGGGAGTTTGTGTGGAAGAGTCACAAA
TGGGACCGGGAGTTAATCTCAGAGAGATGGAAGAATTTCCCCAGCCCTGTGGATGCTGCA
TTCCGTCAAGGTCACAACAGTGTCTTTCTGATCAAGGGGGACAAAGTCTGGGTATACCCT
CCTGAAAAGAAGGAGAAAGGATACCCAAAGTTGCTCCAAGATGAATTTCCTGGAATCCCA
TCCCCACTGGATGCAGCTGTGGAATGTCACCGTGGAGAATGTCAAGCTGAAGGCGTCCTC
TTCTTCCAAGGTGACCGCGAGTGGTTCTGGGACTTGGCTACGGGAACCATGAAGGAGCGT
TCCTGGCCAGCTGTTGGGAACTGCTCCTCTGCCCTGAGATGGCTGGGCCGCTACTACTGC
TTCCAGGGTAACCAATTCCTGCGCTTCGACCCTGTCAGGGGAGAGGTGCCTCCCAGGTAC
CCGCGGGATGTCCGAGACTACTTCATGCCCTGCCCTGGCAGAGGCCATGGACACAGGAAT
GGGACTGGCCATGGGAACAGTACCCACCATGGCCCTGAGTATATGCGCTGTAGCCCACAT
CTAGTCTTGTCTGCACTGACGTCTGACAACCATGGTGCCACCTATGCCTTCAGTGGGACC
CACTACTGGCGTCTGGACACCAGCCGGGATGGCTGGCATAGCTGGCCCATTGCTCATCAG
TGGCCCCAGGGTCCTTCAGCAGTGGATGCTGCCTTTTCCTGGGAAGAAAAACTCTATCTG
GTCCAGGGCACCCAGGTATATGTCTTCCTGACAAAGGGAGGCTATACCCTAGTAAGCGGT
TATCCGAAGCGGCTGGAGAAGGAAGTCGGGACCCCTCATGGGATTATCCTGGACTCTGTG
GATGCGGCCTTTATCTGCCCTGGGTCTTCTCGGCTCCATATCATGGCAGGACGGCGGCTG
TGGTGGCTGGACCTGAAGTCAGGAGCCCAAGCCACGTGGACAGAGCTTCCTTGGCCCCAT
GAGAAGGTAGACGGAGCCTTGTGTATGGAAAGGTCCCTTGGCCCTAACTCATGTTCCGCC
AATGGTCCCGGCTTGTACCTCATCCATGGTCCCAATTTGTACTGCTACAGTGATGTGGAG
AAACTGAATGCAGCCAAGGCCCTTCCGCAACCCCAGAATGTGACCAGTCTCCTGGGCTGC
ACTCACTGA
|
| Protein Properties |
|---|
| Number of Residues
| 462 |
| Molecular Weight
| 51676.0 |
| Theoretical pI
| 7.02 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Hemopexin
MARVLGAPVALGLWSLCWSLAIATPLPPTSAHGNVAEGETKPDPDVTERCSDGWSFDATT
LDDNGTMLFFKGEFVWKSHKWDRELISERWKNFPSPVDAAFRQGHNSVFLIKGDKVWVYP
PEKKEKGYPKLLQDEFPGIPSPLDAAVECHRGECQAEGVLFFQGDREWFWDLATGTMKER
SWPAVGNCSSALRWLGRYYCFQGNQFLRFDPVRGEVPPRYPRDVRDYFMPCPGRGHGHRN
GTGHGNSTHHGPEYMRCSPHLVLSALTSDNHGATYAFSGTHYWRLDTSRDGWHSWPIAHQ
WPQGPSAVDAAFSWEEKLYLVQGTQVYVFLTKGGYTLVSGYPKRLEKEVGTPHGIILDSV
DAAFICPGSSRLHIMAGRRLWWLDLKSGAQATWTELPWPHEKVDGALCMEKSLGPNSCSA
NGPGLYLIHGPNLYCYSDVEKLNAAKALPQPQNVTSLLGCTH
|
| External Links |
|---|
| GenBank ID Protein
| 189053897 |
| UniProtKB/Swiss-Prot ID
| P02790 |
| UniProtKB/Swiss-Prot Entry Name
| HEMO_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AK313648 |
| GeneCard ID
| HPX |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |