| Identification |
|---|
| HMDB Protein ID
| CDBP01506 |
| Secondary Accession Numbers
| Not Available |
| Name
| Hemoglobin subunit beta |
| Description
| Not Available |
| Synonyms
|
- Beta-globin
- Hemoglobin beta chain
- LVV-hemorphin-7
|
| Gene Name
| HBB |
| Protein Type
| Metal Binding |
| Biological Properties |
|---|
| General Function
| Involved in iron ion binding |
| Specific Function
| LVV-hemorphin-7 potentiates the activity of bradykinin, causing a decrease in blood pressure |
| GO Classification
|
| Component |
| macromolecular complex |
| protein complex |
| hemoglobin complex |
| Function |
| ion binding |
| cation binding |
| metal ion binding |
| binding |
| transition metal ion binding |
| iron ion binding |
| heme binding |
| oxygen binding |
| Process |
| establishment of localization |
| transport |
| gas transport |
| oxygen transport |
|
| Cellular Location
|
Not Available
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 11p15.5 |
| SNPs
| HBB |
| Gene Sequence
|
>444 bp
ATGGTGCATCTGACTCCTGAGGAGAAGTCTGCCGTTACTGCCCTGTGGGGCAAGGTGAAC
GTGGATGAAGTTGGTGGTGAGGCCCTGGGCAGGCTGCTGGTGGTCTACCCTTGGACCCAG
AGGTTCTTTGAGTCCTTTGGGGATCTGTCCACTCCTGATGCTGTTATGGGCAACCCTAAG
GTGAAGGCTCATGGCAAGAAAGTGCTCGGTGCCTTTAGTGATGGCCTGGCTCACCTGGAC
AACCTCAAGGGCACCTTTGCCACACTGAGTGAGCTGCACTGTGACAAGCTGCACGTGGAT
CCTGAGAACTTCAGGCTCCTGGGCAACGTGCTGGTCTGTGTGCTGGCCCATCACTTTGGC
AAAGAATTCACCCCACCAGTGCAGGCTGCCTATCAGAAAGTGGTGGCTGGTGTGGCTAAT
GCCCTGGCCCACAAGTATCACTAA
|
| Protein Properties |
|---|
| Number of Residues
| 147 |
| Molecular Weight
| 15998.3 |
| Theoretical pI
| 7.32 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Hemoglobin subunit beta
MVHLTPEEKSAVTALWGKVNVDEVGGEALGRLLVVYPWTQRFFESFGDLSTPDAVMGNPK
VKAHGKKVLGAFSDGLAHLDNLKGTFATLSELHCDKLHVDPENFRLLGNVLVCVLAHHFG
KEFTPPVQAAYQKVVAGVANALAHKYH
|
| External Links |
|---|
| GenBank ID Protein
| 2253432 |
| UniProtKB/Swiss-Prot ID
| P68871 |
| UniProtKB/Swiss-Prot Entry Name
| HBB_HUMAN |
| PDB IDs
|
|
| GenBank Gene ID
| AF007546 |
| GeneCard ID
| HBB |
| GenAtlas ID
| HBB |
| HGNC ID
| HGNC:4827 |
| References |
|---|
| General References
| Not Available |