| Identification |
|---|
| HMDB Protein ID
| CDBP01503 |
| Secondary Accession Numbers
| Not Available |
| Name
| Cholesteryl ester transfer protein |
| Description
| Not Available |
| Synonyms
|
- Lipid transfer protein I
|
| Gene Name
| CETP |
| Protein Type
| Transporter |
| Biological Properties |
|---|
| General Function
| Involved in lipid binding |
| Specific Function
| Involved in the transfer of insoluble cholesteryl esters in the reverse transport of cholesterol |
| GO Classification
|
| Component |
| macromolecular complex |
| protein-lipid complex |
| plasma lipoprotein particle |
| high-density lipoprotein particle |
| Function |
| cholesterol transporter activity |
| lipid transporter activity |
| lipid binding |
| binding |
| transporter activity |
| substrate-specific transporter activity |
| sterol transporter activity |
| Process |
| establishment of localization |
| transport |
| sterol transport |
| cholesterol transport |
| reverse cholesterol transport |
| lipid transport |
|
| Cellular Location
|
- Secreted
- extracellular space
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 16q21 |
| SNPs
| CETP |
| Gene Sequence
|
>1482 bp
ATGCTGGCTGCCACAGTCCTGACCCTGGCCCTGCTGGGCAATGCCCATGCCTGCTCCAAA
GGCACCTCGCACGAGGCAGGCATCGTGTGCCGCATCACCAAGCCTGCCCTCCTGGTGTTG
AACCACGAGACTGCCAAGGTGATCCAGACCGCCTTCCAGCGAGCCAGCTACCCAGATATC
ACGGGCGAGAAGGCCATGATGCTCCTTGGCCAAGTCAAGTATGGGTTGCACAACATCCAG
ATCAGCCACTTGTCCATCGCCAGCAGCCAGGTGGAGCTGGTGGAAGCCAAGTCCATTGAT
GTCTCCATTCAGAACGTGTCTGTGGTCTTCAAGGGGACCCTGAAGTATGGCTACACCACT
GCCTGGTGGCTGGGTATTGATCAGTCCATTGACTTCGAGATCGACTCTGCCATTGACCTC
CAGATCAACACACAGCTGACCTGTGACTCTGGTAGAGTGCGGACCGATGCCCCTGACTGC
TACCTGTCTTTCCATAAGCTGCTCCTGCATCTCCAAGGGGAGCGAGAGCCTGGGTGGATC
AAGCAGCTGTTCACAAATTTCATCTCCTTCACCCTGAAGCTGGTCCTGAAGGGACAGATC
TGCAAAGAGATCAACGTCATCTCTAACATCATGGCCGATTTTGTCCAGACAAGGGCTGCC
AGCATCCTTTCAGATGGAGACATTGGGGTGGACATTTCCCTGACAGGTGATCCCGTCATC
ACAGCCTCCTACCTGGAGTCCCATCACAAGGGTCATTTCATCTACAAGAATGTCTCAGAG
GACCTCCCCCTCCCCACCTTCTCGCCCACACTGCTGGGGGACTCCCGCATGCTGTACTTC
TGGTTCTCTGAGCGAGTCTTCCACTCGCTGGCCAAGGTAGCTTTCCAGGATGGCCGCCTC
ATGCTCAGCCTGATGGGAGACGAGTTCAAGGCAGTGCTGGAGACCTGGGGCTTCAACACC
AACCAGGAAATCTTCCAAGAGGTTGTCGGCGGCTTCCCCAGCCAGGCCCAAGTCACCGTC
CACTGCCTCAAGATGCCCAAGATCTCCTGCCAAAACAAGGGAGTCGTGGTCAATTCTTCA
GTGATGGTGAAATTCCTCTTTCCACGCCCAGACCAGCAACATTCTGTAGCTTACACATTT
GAAGAGGATATCGTGACTACCGTCCAGGCCTCCTATTCTAAGAAAAAGCTCTTCTTAAGC
CTCTTGGATTTCCAGATTACACCAAAGACTGTTTCCAACTTGACTGAGAGCAGCTCCGAG
TCCATCCAGAGCTTCCTGCAGTCAATGATCACCGCTGTGGGCATCCCTGAGGTCATGTCT
CGGCTCGAGGTAGTGTTTACAGCCCTCATGAACAGCAAAGGCGTGAGCCTCTTCGACATC
ATCAACCCTGAGATTATCACTCGAGATGGCTTCCTGCTGCTGCAGATGGACTTTGGCTTC
CCTGAGCACCTGCTGGTGGATTTCCTCCAGAGCTTGAGCTAG
|
| Protein Properties |
|---|
| Number of Residues
| 493 |
| Molecular Weight
| 54755.7 |
| Theoretical pI
| 6.02 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Cholesteryl ester transfer protein
MLAATVLTLALLGNAHACSKGTSHEAGIVCRITKPALLVLNHETAKVIQTAFQRASYPDI
TGEKAMMLLGQVKYGLHNIQISHLSIASSQVELVEAKSIDVSIQNVSVVFKGTLKYGYTT
AWWLGIDQSIDFEIDSAIDLQINTQLTCDSGRVRTDAPDCYLSFHKLLLHLQGEREPGWI
KQLFTNFISFTLKLVLKGQICKEINVISNIMADFVQTRAASILSDGDIGVDISLTGDPVI
TASYLESHHKGHFIYKNVSEDLPLPTFSPTLLGDSRMLYFWFSERVFHSLAKVAFQDGRL
MLSLMGDEFKAVLETWGFNTNQEIFQEVVGGFPSQAQVTVHCLKMPKISCQNKGVVVNSS
VMVKFLFPRPDQQHSVAYTFEEDIVTTVQASYSKKKLFLSLLDFQITPKTVSNLTESSSE
SVQSFLQSMITAVGIPEVMSRLEVVFTALMNSKGVSLFDIINPEIITRDGFLLLQMDFGF
PEHLLVDFLQSLS
|
| External Links |
|---|
| GenBank ID Protein
| 180260 |
| UniProtKB/Swiss-Prot ID
| P11597 |
| UniProtKB/Swiss-Prot Entry Name
| CETP_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| M30185 |
| GeneCard ID
| CETP |
| GenAtlas ID
| CETP |
| HGNC ID
| HGNC:1869 |
| References |
|---|
| General References
| Not Available |