Cannabis Compound Database: Showing Protein Phosphomannomutase 2 (CDBP01491)

Identification Biological properties Gene properties Protein properties External links References XML Show 3 compounds

Identification

HMDB Protein ID

CDBP01491

Secondary Accession Numbers

Not Available

Name

Phosphomannomutase 2

Description

Not Available

Synonyms

PMM 2

Gene Name

PMM2

Protein Type

Enzyme

Biological Properties

General Function

Involved in catalytic activity

Specific Function

Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions (By similarity).

GO Classification

Biological Process
dolichol-linked oligosaccharide biosynthetic process
post-translational protein modification
protein N-linked glycosylation via asparagine
mannose biosynthetic process
GDP-mannose biosynthetic process
Cellular Component
cytosol
neuronal cell body
Component
cell part
intracellular part
cytoplasm
Function
isomerase activity
phosphomannomutase activity
intramolecular transferase activity
intramolecular transferase activity, phosphotransferases
catalytic activity
Molecular Function
phosphomannomutase activity
Process
metabolic process
mannose metabolic process
small molecule metabolic process
alcohol metabolic process
monosaccharide metabolic process
hexose metabolic process
mannose biosynthetic process

Cellular Location

Cytoplasm

Pathways

Name	SMPDB/Pathwhiz	KEGG
GDP-alpha-D-mannose biosynthesis	Not Available	Not Available
Fructose and mannose metabolism	Not Available
Amino sugar and nucleotide sugar metabolism	Not Available

Gene Properties

Chromosome Location

Locus

16p13

SNPs

PMM2

Gene Sequence

>741 bp
ATGGCAGCGCCTGGCCCAGCGCTCTGCCTCTTCGACGTGGATGGGACCCTCACCGCCCCG
CGGCAGAAAATTACCAAAGAAATGGATGACTTCCTACAAAAATTGAGGCAGAAGATCAAA
ATCGGAGTGGTAGGCGGATCGGACTTTGAGAAAGTGCAGGAGCAACTGGGAAATGATGTG
GTTGAAAAATACGATTATGTGTTTCCAGAAAATGGCTTGGTAGCATACAAAGATGGGAAA
CTCTTGTGTAGACAGAATATTCAAAGTCATCTGGGTGAGGCCCTAATCCAAGATTTAATC
AACTACTGTCTGAGCTACATTGCGAAAATTAAACTCCCGAAGAAGAGGGGTACTTTCATT
GAATTCCGAAATGGGATGTTAAACGTGTCCCCTATTGGAAGAAGCTGCAGCCAAGAAGAA
CGCATTGAGTTCTACGAACTCGATAAAAAAGAAAATATAAGACAAAAGTTTGTAGCAGAT
CTACGGAAAGAGTTTGCTGGAAAAGGCCTCACGTTTTCCATAGGAGGCCAGATCAGCTTT
GATGTCTTTCCTGATGGATGGGACAAGAGATACTGTCTGCGACATGTGGAAAATGACGGT
TATAAGACCATTTATTTCTTTGGAGACAAAACTATGCCAGGTGGCAATGACCATGAGATC
TTCACAGACCCCAGAACCATGGGCTACTCCGTGACAGCGCCTGAGGACACGCGCAGGATC
TGTGAACTGCTGTTCTCCTAA

Protein Properties

Number of Residues

246

Molecular Weight

28081.925

Theoretical pI

6.778

Pfam Domain Function

PMM (PF03332 )

Signals

Not Available

Transmembrane Regions

Not Available

Protein Sequence

>Phosphomannomutase 2
MAAPGPALCLFDVDGTLTAPRQKITKEMDDFLQKLRQKIKIGVVGGSDFEKVQEQLGNDV
VEKYDYVFPENGLVAYKDGKLLCRQNIQSHLGEALIQDLINYCLSYIAKIKLPKKRGTFI
EFRNGMLNVSPIGRSCSQEERIEFYELDKKENIRQKFVADLRKEFAGKGLTFSIGGQISF
DVFPDGWDKRYCLRHVENDGYKTIYFFGDKTMPGGNDHEIFTDPRTMGYSVTAPEDTRRI
CELLFS

External Links

GenBank ID Protein

2218087

UniProtKB/Swiss-Prot ID

O15305

UniProtKB/Swiss-Prot Entry Name

PMM2_HUMAN

PDB IDs