Showing Protein N-acetylglucosamine-6-sulfatase (CDBP01483)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 3 compounds
Identification
HMDB Protein ID CDBP01483
Secondary Accession Numbers Not Available
Name N-acetylglucosamine-6-sulfatase
Description Not Available
Synonyms
  1. G6S
  2. Glucosamine-6-sulfatase
Gene Name GNS
Protein Type Enzyme
Biological Properties
General Function Involved in catalytic activity
Specific Function Not Available
GO Classification
Biological Process
keratan sulfate catabolic process
carbohydrate metabolic process
Cellular Component
lysosomal lumen
Component
organelle
membrane-bounded organelle
intracellular membrane-bounded organelle
vacuole
lytic vacuole
lysosome
Function
catalytic activity
hydrolase activity
sulfuric ester hydrolase activity
n-acetylglucosamine-6-sulfatase activity
hydrolase activity, acting on ester bonds
Molecular Function
metal ion binding
glycosaminoglycan binding
N-acetylglucosamine-6-sulfatase activity
sulfate binding
Process
polysaccharide metabolic process
aminoglycan metabolic process
glycosaminoglycan metabolic process
metabolic process
primary metabolic process
carbohydrate metabolic process
Cellular Location
  1. Lysosome
Pathways
Gene Properties
Chromosome Location Not Available
Locus Not Available
SNPs GNS
Gene Sequence 
>1659 bp
ATGCGGCTCCTGCCTCTAGCCCCAGGTCGGCTCCGGCGGGGCAGCCCCCGCCACCTGCCC
TCCTGCAGCCCAGCGCTGCTACTGCTGGTGCTGGGCGGCTGCCTGGGGGTCTTCGGGGTG
GCTGCGGGAACCCGGAGGCCCAACGTGGTGCTGCTCCTCACGGACGACCAGGACGAAGTG
CTCGGCGGCATGACACCACTAAAGAAAACCAAAGCTCTCATCGGAGAGATGGGGATGACT
TTTTCCAGTGCTTATGTGCCAAGTGCTCTCTGCTGCCCCAGCAGAGCCAGTATCCTGACA
GGAAAGTACCCACATAATCATCACGTTGTGAACAACACTCTGGAGGGGAACTGCAGTAGT
AAGTCCTGGCAGAAGATCCAAGAACCAAATACTTTCCCAGCAATTCTCAGATCAATGTGT
GGTTATCAGACCTTTTTTGCAGGGAAATATTTAAATGAGTACGGAGCCCCAGATGCAGGT
GGACTAGAACACGTTCCTCTGGGTTGGAGTTACTGGTATGCCTTGGAAAAGAATTCTAAG
TATTATAATTACACCCTGTCTATCAATGGGAAGGCACGGAAGCATGGTGAAAACTATAGT
GTGGACTACCTGACAGATGTTTTGGCTAATGTCTCCTTGGACTTTCTGGACTACAAGTCC
AACTTTGAGCCCTTCTTCATGATGATCGCCACTCCAGCGCCTCATTCGCCTTGGACAGCT
GCACCTCAGTACCAGAAGGCTTTCCAGAATGTCTTTGCACCAAGAAACAAGAACTTCAAC
ATCCATGGAACGAACAAGCACTGGTTAATTAGGCAAGCCAAGACTCCAATGACTAATTCT
TCAATACAGTTTTTAGATAATGCATTTAGGAAAAGGTGGCAAACTCTCCTCTCAGTTGAT
GACCTTGTGGAGAAACTGGTCAAGAGGCTGGAGTTCACTGGGGAGCTCAACAACACTTAC
ATCTTCTATACCTCAGACAATGGCTATCACACAGGACAGTTTTCCTTGCCAATAGACAAG
AGACAGCTGTATGAGTTTGATATCAAAGTTCCACTGTTGGTTCGAGGACCTGGGATCAAA
CCAAATCAGACAAGCAAGATGCTGGTTGCCAACATTGACTTGGGTCCTACTATTTTGGAC
ATTGCTGGCTACGACCTAAATAAGACACAGATGGATGGGATGTCCTTATTGCCCATTTTG
AGAGGTGCCAGTAACTTGACCTGGCGATCAGATGTCCTGGTGGAATACCAAGGAGAAGGC
CGTAACGTCACTGACCCAACATGCCCTTCCCTGAGTCCTGGCGTATCTCAATGCTTCCCA
GACTGTGTATGTGAAGATGCTTATAACAATACCTATGCCTGTGTGAGGACAATGTCAGCA
TTGTGGAATTTGCAGTATTGCGAGTTTGATGACCAGGAGGTGTTTGTAGAAGTCTATAAT
CTGACTGCAGACCCAGACCAGATCACTAACATTGCTAAAACCATAGACCCAGAGCTTTTA
GGAAAGATGAACTATCGGTTAATGATGTTACAGTCCTGTTCTGGGCCAACCTGTCGCACT
CCAGGGGTTTTTGACCCCGGATACAGGTTTGACCCCCGTCTCATGTTCAGCAATCGCGGC
AGTGTCAGGACTCGAAGATTTTCCAAACATCTTCTGTAG
Protein Properties
Number of Residues 552
Molecular Weight Not Available
Theoretical pI Not Available
Pfam Domain Function
Signals Not Available
Transmembrane Regions Not Available
Protein Sequence 
>N-acetylglucosamine-6-sulfatase
MRLLPLAPGRLRRGSPRHLPSCSPALLLLVLGGCLGVFGVAAGTRRPNVVLLLTDDQDEV
LGGMTPLKKTKALIGEMGMTFSSAYVPSALCCPSRASILTGKYPHNHHVVNNTLEGNCSS
KSWQKIQEPNTFPAILRSMCGYQTFFAGKYLNEYGAPDAGGLEHVPLGWSYWYALEKNSK
YYNYTLSINGKARKHGENYSVDYLTDVLANVSLDFLDYKSNFEPFFMMIATPAPHSPWTA
APQYQKAFQNVFAPRNKNFNIHGTNKHWLIRQAKTPMTNSSIQFLDNAFRKRWQTLLSVD
DLVEKLVKRLEFTGELNNTYIFYTSDNGYHTGQFSLPIDKRQLYEFDIKVPLLVRGPGIK
PNQTSKMLVANIDLGPTILDIAGYDLNKTQMDGMSLLPILRGASNLTWRSDVLVEYQGEG
RNVTDPTCPSLSPGVSQCFPDCVCEDAYNNTYACVRTMSALWNLQYCEFDDQEVFVEVYN
LTADPDQITNIAKTIDPELLGKMNYRLMMLQSCSGPTCRTPGVFDPGYRFDPRLMFSNRG
SVRTRRFSKHLL
GenBank ID Protein 31867
UniProtKB/Swiss-Prot ID P15586
UniProtKB/Swiss-Prot Entry Name GNS_HUMAN
PDB IDs Not Available
GenBank Gene ID Z12173
GeneCard ID GNS
GenAtlas ID GNS
HGNC ID HGNC:4422
References
General References Not Available