Cannabis Compound Database: Showing Protein 1-acyl-sn-glycerol-3-phosphate acyltransferase beta (CDBP01467)

Identification Biological properties Gene properties Protein properties External links References XML Show 8 compounds

Identification

HMDB Protein ID

CDBP01467

Secondary Accession Numbers

Not Available

Name

1-acyl-sn-glycerol-3-phosphate acyltransferase beta

Description

Not Available

Synonyms

1-AGP acyltransferase 2
1-AGPAT 2
1-acylglycerol-3-phosphate O-acyltransferase 2
LPAAT-beta
Lysophosphatidic acid acyltransferase beta

Gene Name

AGPAT2

Protein Type

Enzyme

Biological Properties

General Function

Lipid transport and metabolism

Specific Function

Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the sn-2 position of the glycerol backbone.

GO Classification

Biological Process
small molecule metabolic process
CDP-diacylglycerol biosynthetic process
positive regulation of cytokine production
positive regulation of cytokine-mediated signaling pathway
phosphatidic acid biosynthetic process
triglyceride biosynthetic process
epidermis development
Cellular Component
endoplasmic reticulum membrane
integral to membrane
Component
membrane
cell part
Function
transferase activity
transferase activity, transferring acyl groups
transferase activity, transferring acyl groups other than amino-acyl groups
acyltransferase activity
acylglycerol o-acyltransferase activity
1-acylglycerol-3-phosphate o-acyltransferase activity
o-acyltransferase activity
catalytic activity
Molecular Function
1-acylglycerol-3-phosphate O-acyltransferase activity
Process
metabolic process
phospholipid biosynthetic process
organophosphate metabolic process
phospholipid metabolic process

Cellular Location

Membrane
Multi-pass membrane protein (Potential)

Pathways

Name	SMPDB/Pathwhiz	KEGG
CDP-diacylglycerol biosynthesis	Not Available	Not Available
Glycerophospholipid metabolism	Not Available
Fat digestion and absorption	Not Available

Gene Properties

Chromosome Location

Locus

9q34.3

SNPs

AGPAT2

Gene Sequence

>837 bp
ATGGAGCTGTGGCCGTGTCTGGCCGCGGCGCTGCTGTTGCTGCTGCTGCTGGTGCAGCTG
AGCCGCGCGGCCGAGTTCTACGCCAAGGTCGCCCTGTACTGCGCGCTGTGCTTCACGGTG
TCCGCCGTGGCCTCGCTCGTCTGCCTGCTGCGCCACGGCGGCCGGACGGTGGAGAACATG
AGCATCATCGGCTGGTTCGTGCGAAGCTTCAAGTACTTTTACGGGCTCCGCTTCGAGGTG
CGGGACCCGCGCAGGCTGCAGGAGGCCCGTCCCTGTGTCATCGTCTCCAACCACCAGAGC
ATCCTGGACATGATGGGCCTCATGGAGGTCCTTCCGGAGCGCTGCGTGCAGATCGCCAAG
CGGGAGCTGCTCTTCCTGGGGCCCGTGGGCCTCATCATGTACCTCGGGGGCGTCTTCTTC
ATCAACCGGCAGCGCTCTAGCACTGCCATGACAGTGATGGCCGACCTGGGCGAGCGCATG
GTCAGGGAGAACCTCAAAGTGTGGATCTATCCCGAGGGTACTCGCAACGACAATGGGGAC
CTGCTGCCTTTTAAGAAGGGCGCCTTCTACCTGGCAGTCCAGGCACAGGTGCCCATCGTC
CCCGTGGTGTACTCTTCCTTCTCCTCCTTCTACAACACCAAGAAGAAGTTCTTCACTTCA
GGAACAGTCACAGTGCAGGTGCTGGAAGCCATCCCCACCAGCGGCCTCACTGCGGCGGAC
GTCCCTGCGCTCGTGGACACCTGCCACCGGGCCATGAGGACCACCTTCCTCCACATCTCC
AAGACCCCCCAGGAGAACGGGGCCACTGCGGGGTCTGGCGTGCAGCCGGCCCAGTAG

Protein Properties

Number of Residues

278

Molecular Weight

27278.915

Theoretical pI

8.913

Pfam Domain Function

Acyltransferase (PF01553 )

Signals

Not Available

Transmembrane Regions

Not Available

Protein Sequence

>1-acyl-sn-glycerol-3-phosphate acyltransferase beta
MELWPCLAAALLLLLLLVQLSRAAEFYAKVALYCALCFTVSAVASLVCLLRHGGRTVENM
SIIGWFVRSFKYFYGLRFEVRDPRRLQEARPCVIVSNHQSILDMMGLMEVLPERCVQIAK
RELLFLGPVGLIMYLGGVFFINRQRSSTAMTVMADLGERMVRENLKVWIYPEGTRNDNGD
LLPFKKGAFYLAVQAQVPIVPVVYSSFSSFYNTKKKFFTSGTVTVQVLEAIPTSGLTAAD
VPALVDTCHRAMRTTFLHISKTPQENGATAGSGVQPAQ

External Links

GenBank ID Protein

2282590

UniProtKB/Swiss-Prot ID

O15120

UniProtKB/Swiss-Prot Entry Name

PLCB_HUMAN

PDB IDs

Not Available

GenBank Gene ID

AF000237

GeneCard ID