Cannabis Compound Database: Showing Protein Isopentenyl-diphosphate Delta-isomerase 2 (CDBP01428)

Identification Biological properties Gene properties Protein properties External links References XML Show 3 compounds

Identification

HMDB Protein ID

CDBP01428

Secondary Accession Numbers

Not Available

Name

Isopentenyl-diphosphate Delta-isomerase 2

Description

Not Available

Synonyms

IPP isomerase 2
IPPI2
Isopentenyl pyrophosphate isomerase 2

Gene Name

IDI2

Protein Type

Enzyme

Biological Properties

General Function

Lipid transport and metabolism

Specific Function

Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).

GO Classification

Biological Process
isoprenoid biosynthetic process
cholesterol biosynthetic process
dimethylallyl diphosphate biosynthetic process
Cellular Component
cytosol
peroxisome
Function
catalytic activity
hydrolase activity
intramolecular oxidoreductase activity, transposing c=c bonds
isopentenyl-diphosphate delta-isomerase activity
isomerase activity
intramolecular oxidoreductase activity
Molecular Function
metal ion binding
isopentenyl-diphosphate delta-isomerase activity
hydrolase activity
Process
metabolic process
primary metabolic process
lipid metabolic process
cellular lipid metabolic process
isoprenoid metabolic process
isoprenoid biosynthetic process

Cellular Location

Peroxisome

Pathways

Name	SMPDB/Pathwhiz	KEGG
dimethylallyl diphosphate biosynthesis	Not Available	Not Available
Terpenoid backbone biosynthesis	Not Available

Gene Properties

Chromosome Location

Locus

10p15.3

SNPs

IDI2

Gene Sequence

>684 bp
ATGTCTGACATAAATCTTGACTGGGTTGACAGGCGTCAGTTGCAGCGCTTGGAGGAAATG
CTGATTGTTGTGGATGAGAATGATAAGGTTATTGGTGCCGACACCAAGAGGAATTGCCAT
CTGAACGAAAACATTGAGAAAGGGCTGCTGCACCGAGCCTTCAGCGTTGTCTTGTTTAAC
ACCAAGAATCGAATCCTGATACAGCAGAGGTCGGACACGAAAGTCACGTTTCCTGGGTAT
TTTACCGACTCCTGTAGTAGCCACCCATTATACAACCCAGCAGAACTGGAAGAAAAGGAT
GCCATCGGAGTGAGGAGGGCAGCCCAGAGGCGTCTGCAAGCAGAGCTGGGAATTCCTGGG
GAACAGATTTCTCCAGAGGACATTGTGTTCATGACAATCTATCACCACAAGGCAAAATCA
GACAGAATTTGGGGAGAGCATGAAATTTGTTACCTTCTGCTTGTGAGGAAAAACGTCACT
CTGAACCCGGATCCCAGTGAAACGAAAAGCATCCTCTACCTGTCCCAGGAGGAGCTGTGG
GAGCTGCTGGAGAGGGAGGCGAGGGGTGAAGTCAAAGTCACCCCCTGGCTAAGAACCATT
GCCGAGAGGTTTCTGTACCGGTGGTGGCCTCACCTGGATGACGTGACCCCGTTTGTGGAG
CTTCACAAAATACACAGAGTGTGA

Protein Properties

Number of Residues

227

Molecular Weight

26752.33

Theoretical pI

6.453

Pfam Domain Function

NUDIX (PF00293 )

Signals

Not Available

Transmembrane Regions

Not Available

Protein Sequence

>Isopentenyl-diphosphate Delta-isomerase 2
MSDINLDWVDRRQLQRLEEMLIVVDENDKVIGADTKRNCHLNENIEKGLLHRAFSVVLFN
TKNRILIQQRSDTKVTFPGYFTDSCSSHPLYNPAELEEKDAIGVRRAAQRRLQAELGIPG
EQISPEDIVFMTIYHHKAKSDRIWGEHEICYLLLVRKNVTLNPDPSETKSILYLSQEELW
ELLEREARGEVKVTPWLRTIAERFLYRWWPHLDDVTPFVELHKIHRV

External Links

GenBank ID Protein

13925769

UniProtKB/Swiss-Prot ID

Q9BXS1

UniProtKB/Swiss-Prot Entry Name

IDI2_HUMAN

PDB IDs