| Identification |
|---|
| HMDB Protein ID
| CDBP01379 |
| Secondary Accession Numbers
| Not Available |
| Name
| V-type proton ATPase subunit e 1 |
| Description
| Not Available |
| Synonyms
|
- V-ATPase 9.2 kDa membrane accessory protein
- V-ATPase M9.2 subunit
- V-ATPase subunit e 1
- Vacuolar proton pump subunit e 1
|
| Gene Name
| ATP6V0E1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in hydrogen ion transmembrane transporter activity |
| Specific Function
| Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells |
| GO Classification
|
| Component |
| macromolecular complex |
| protein complex |
| proton-transporting two-sector atpase complex, proton-transporting domain |
| proton-transporting v-type atpase, v0 domain |
| Function |
| substrate-specific transmembrane transporter activity |
| ion transmembrane transporter activity |
| cation transmembrane transporter activity |
| inorganic cation transmembrane transporter activity |
| monovalent inorganic cation transmembrane transporter activity |
| hydrogen ion transmembrane transporter activity |
| transporter activity |
| transmembrane transporter activity |
| Process |
| nucleoside phosphate metabolic process |
| nucleotide metabolic process |
| atp synthesis coupled proton transport |
| hydrogen transport |
| proton transport |
| establishment of localization |
| transport |
| purine nucleotide metabolic process |
| energy coupled proton transport, against electrochemical gradient |
| purine nucleotide biosynthetic process |
| atp hydrolysis coupled proton transport |
| purine nucleoside triphosphate biosynthetic process |
| atp biosynthetic process |
| purine ribonucleoside triphosphate biosynthetic process |
| metabolic process |
| nitrogen compound metabolic process |
| cellular nitrogen compound metabolic process |
| nucleobase, nucleoside, nucleotide and nucleic acid metabolic process |
| nucleobase, nucleoside and nucleotide metabolic process |
|
| Cellular Location
|
- Membrane
- Multi-pass membrane protein (Potential)
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:5 |
| Locus
| 5q35.1 |
| SNPs
| ATP6V0E1 |
| Gene Sequence
|
>246 bp
ATGGCGTATCACGGCCTCACTGTGCCTCTCATTGTGATGAGCGTGTTCTGGGGCTTCGTC
GGCTTCTTGGTGCCTTGGTTCATCCCTAAGGGTCCTAACCGGGGAGTTATCATTACCATG
TTGGTGACCTGTTCAGTTTGCTGCTATCTCTTTTGGCTGATTGCAATTCTGGCCCAACTC
AACCCTCTCTTTGGACCGCAATTGAAAAATGAAACCATCTGGTATCTGAAGTATCATTGG
CCTTGA
|
| Protein Properties |
|---|
| Number of Residues
| 81 |
| Molecular Weight
| 9374.3 |
| Theoretical pI
| 8.87 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>V-type proton ATPase subunit e 1
MAYHGLTVPLIVMSVFWGFVGFLVPWFIPKGPNRGVIITMLVTCSVCCYLFWLIAILAQL
NPLFGPQLKNETIWYLKYHWP
|
| External Links |
|---|
| GenBank ID Protein
| 2584789 |
| UniProtKB/Swiss-Prot ID
| O15342 |
| UniProtKB/Swiss-Prot Entry Name
| VA0E1_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| Y15286 |
| GeneCard ID
| ATP6V0E1 |
| GenAtlas ID
| ATP6V0E1 |
| HGNC ID
| HGNC:863 |
| References |
|---|
| General References
| Not Available |