Showing Protein V-type proton ATPase 16 kDa proteolipid subunit (CDBP01374)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 3 compounds
Identification
HMDB Protein ID CDBP01374
Secondary Accession Numbers Not Available
Name V-type proton ATPase 16 kDa proteolipid subunit
Description Not Available
Synonyms
  1. V-ATPase 16 kDa proteolipid subunit
  2. Vacuolar proton pump 16 kDa proteolipid subunit
Gene Name ATP6V0C
Protein Type Enzyme
Biological Properties
General Function Involved in hydrogen ion transmembrane transporter activity
Specific Function Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells
GO Classification
Component
macromolecular complex
protein complex
proton-transporting two-sector atpase complex, proton-transporting domain
proton-transporting v-type atpase, v0 domain
proton-transporting atp synthase complex, coupling factor f(o)
Function
ion transmembrane transporter activity
cation transmembrane transporter activity
inorganic cation transmembrane transporter activity
monovalent inorganic cation transmembrane transporter activity
hydrogen ion transmembrane transporter activity
transporter activity
transmembrane transporter activity
substrate-specific transmembrane transporter activity
Process
nucleotide metabolic process
atp synthesis coupled proton transport
atp biosynthetic process
purine nucleotide metabolic process
purine nucleotide biosynthetic process
purine nucleoside triphosphate biosynthetic process
purine ribonucleoside triphosphate biosynthetic process
metabolic process
nitrogen compound metabolic process
cellular nitrogen compound metabolic process
nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
nucleobase, nucleoside and nucleotide metabolic process
nucleoside phosphate metabolic process
Cellular Location
  1. Multi-pass membrane protein
  2. Vacuole membrane
Pathways
Gene Properties
Chromosome Location Chromosome:1
Locus 16p13.3
SNPs ATP6V0C
Gene Sequence 
>468 bp
ATGTCCGAGTCCAAGAGCGGCCCCGAGTATGCTTCGTTTTTCGCCGTCATGGGCGCCTCG
GCCGCCATGGTCTTCAGCGCCCTGGGCGCTGCCTATGGCACAGCCAAGAGCGGTACCGGC
ATTGCGGCCATGTCTGTCATGCGGCCGGAGCAGATCATGAAGTCCATCATCCCAGTGGTC
ATGGCTGGCATCATCGCCATCTACGGCCTGGTGGTGGCAGTCCTCATCGCCAACTCCCTG
AATGACGACATCAGCCTCTACAAGAGCTTCCTCCAGCTGGGCGCCGGCCTGAGCGTGGGC
CTGAGCGGCCTGGCAGCCGGCTTTGCCATCGGCATCGTGGGGGACGCTGGCGTGCGGGGC
ACCGCCCAGCAGCCCCGACTATTCGTGGGCATGATCCTGATTCTCATCTTCGCCGAGGTG
CTCGGCCTCTACGGTCTCATCGTCGCCCTCATCCTCTCCACAAAGTAG
Protein Properties
Number of Residues 155
Molecular Weight 15735.6
Theoretical pI 8.88
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["11-33", "56-76", "93-114", "132-152"]
Protein Sequence 
>V-type proton ATPase 16 kDa proteolipid subunit
MSESKSGPEYASFFAVMGASAAMVFSALGAAYGTAKSGTGIAAMSVMRPEQIMKSIIPVV
MAGIIAIYGLVVAVLIANSLNDDISLYKSFLQLGAGLSVGLSGLAAGFAIGIVGDAGVRG
TAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK
GenBank ID Protein 13528675
UniProtKB/Swiss-Prot ID P27449
UniProtKB/Swiss-Prot Entry Name VATL_HUMAN
PDB IDs Not Available
GenBank Gene ID BC004537
GeneCard ID ATP6V0C
GenAtlas ID ATP6V0C
HGNC ID HGNC:855
References
General References Not Available