Cannabis Compound Database: Showing Protein Probable phospholipid-transporting ATPase IIB (CDBP01347)

Identification Biological properties Gene properties Protein properties External links References XML Show 3 compounds

Identification

HMDB Protein ID

CDBP01347

Secondary Accession Numbers

Not Available

Name

Probable phospholipid-transporting ATPase IIB

Description

Not Available

Synonyms

ATPase class II type 9B

Gene Name

ATP9B

Protein Type

Enzyme

Biological Properties

General Function

Involved in ATP binding

Specific Function

ATP + H(2)O + phospholipid(In) = ADP + phosphate + phospholipid(Out)

GO Classification

Component
membrane
cell part
membrane part
intrinsic to membrane
integral to membrane
Function
phospholipid transporter activity
metal ion binding
phospholipid-translocating atpase activity
binding
atpase activity, coupled to transmembrane movement of ions
catalytic activity
hydrolase activity
atpase activity, coupled to transmembrane movement of ions, phosphorylative mechanism
nucleoside binding
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
purine nucleoside binding
hydrolase activity, acting on acid anhydrides
adenyl nucleotide binding
adenyl ribonucleotide binding
atp binding
magnesium ion binding
transmembrane transporter activity
substrate-specific transmembrane transporter activity
ion transmembrane transporter activity
transporter activity
substrate-specific transporter activity
ion binding
lipid transporter activity
cation binding
Process
nucleotide metabolic process
establishment of localization
transport
lipid transport
phospholipid transport
atp biosynthetic process
purine nucleotide metabolic process
purine nucleotide biosynthetic process
purine nucleoside triphosphate biosynthetic process
purine ribonucleoside triphosphate biosynthetic process
metabolic process
nitrogen compound metabolic process
cellular nitrogen compound metabolic process
nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
nucleobase, nucleoside and nucleotide metabolic process
nucleoside phosphate metabolic process

Cellular Location

Membrane
Multi-pass membrane protein

Pathways

Not Available

Gene Properties

Chromosome Location

Chromosome:1

Locus

18q23

SNPs

ATP9B

Gene Sequence

>3444 bp
ATGGCGGACCAGATCCCGCTTTACCCGGTGCGTAGCGCAGCGGCGGCCGCAGCCAACCGC
AAACGCGCGGCCTACTACAGCGCCGCGGGGCCCAGGCCGGGAGCCGACCGGCACAGCAGG
TACCAGCTGGAGGATGAGTCTGCGCATTTGGATGAAATGCCACTAATGATGTCTGAAGAA
GGCTTTGAGAATGAGGAAAGTGATTACCACACCTTACCACGAGCCAGGATAATGCAAAGG
AAAAGAGGACTGGAGTGGTTTGTCTGTGATGGCTGGAAGTTCCTCTGTACCAGTTGCTGT
GGTTGGCTGATAAATATTTGTCGAAGAAAGAAAGAGCTGAAAGCTCGCACAGTATGGCTT
GGATGTCCTGAAAAGTGTGAAGAAAAACATCCCAGGAATTCTATAAAAAATCAAAAATAC
AATGTGTTTACCTTTATACCTGGGGTTTTGTATGAACAATTCAAGTTTTTCTTGAATCTC
TATTTTCTAGTAATATCCTGCTCACAGTTTGTACCAGCATTGAAAATAGGCTATCTCTAC
ACCTACTGGGCTCCTCTGGGATTTGTCTTGGCTGTTACTATGACACGGGAAGCAATTGAT
GAATTTCGGCGTTTTCAGCGTGACAAGGAAGTGAATTCACAACTATATAGCAAGCTTACA
GTAAGAGGTAAAGTGCAAGTTAAGAGTTCAGACATACAAGTTGGAGACCTCATCATAGTG
GAAAAGAATCAAAGAATTCCATCGGACATGGTGTTTCTTAGGACTTCAGAAAAAGCAGGT
TCGTGTTTTATTCGAACTGATCAACTAGATGGTGAAACTGACTGGAAGCTGAAGGTGGCA
GTGAGCTGCACGCAACAGCTGCCGGCTCTGGGGGACCTTTTTTCTATCAGTGCTTATGTT
TATGCTCAGAAACCACAAATGGACATTCACAGTTTCGAAGGCACATTTACCAGGGAAGAC
AGTGACCCGCCCATTCATGAAAGTCTCAGCATAGAAAATACATTGTGGGCAAGCACCATT
GTTGCATCAGGTACTGTAATAGGTGTTGTCATTTATACCGGAAAAGAGACTCGAAGTGTA
ATGAACACATCCAATCCAAAAAATAAGGTTGGTTTGTTGGACCTTGAACTCAATCGGCTG
ACGAAAGCGCTATTTTTGGCTTTAGTTGCTCTTTCCATTGTTATGGTAACCTTACAAGGA
TTTGTGGGTCCATGGTACCGCAATCTTTTTCGGTTCCTTCTCCTCTTTTCTTACATCATT
CCCATAAGTTTGCGTGTGAACTTGGACATGGGCAAAGCGGTGTATGGATGGATGATGATG
AAAGATGAGAACATCCCTGGCACGGTCGTTCGGACCAGCACTATCCCAGAGGAACTTGGG
CGCCTGGTGTATTTATTGACAGACAAAACAGGAACCCTCACCCAGAATGAAATGATATTT
AAGCGGCTGCACCTGGGCACCGTGTCCTATGGCGCCGACACGATGGATGAGATCCAGAGC
CATGTCAGGGACTCCTACTCACAGATGCAGTCTCAAGCTGGTGGAAACAATACTGGTTCA
ACTCCACTAAGAAAAGCCCAATCTTCAGCTCCCAAAGTTAGGAAAAGTGTCAGTAGTCGA
ATCCATGAAGCCGTGAAAGCCATCGTGCTGTGTCACAACGTGACCCCCGTGTATGAGTCT
CGGGCCGGCGTTACTGAGGAGACTGAGTTCGCAGAGGCTGACCAAGACTTCAGTGATGAG
AATCGCACCTACCAGGCTTCCAGCCCGGATGAGGTCGCTCTGGTGCAGTGGACAGAGAGT
GTGGGCCTCACGCTGGTCAGCAGGGACCTCACCTCCATGCAGCTGAAGACCCCCAGTGGC
CAGGTCCTCAGCTTCTGCATTCTGCAGCTGTTTCCCTTCACCTCCGAGAGCAAGCGGATG
GGCGTCATCGTCAGGGATGAATCCACGGCAGAAATCACATTCTACATGAAGGGCGCTGAC
GTGGCCATGTCTCCTATCGTGCAGTATAATGACTGGCTGGAAGAGGAGTGCGGAAACATG
GCTCGCGAAGGACTGCGGACCCTCGTGGTTGCAAAGAAGGCGTTGACAGAGGAGCAGTAC
CAGGACTTTGAGAGCCGATACACTCAAGCCAAGCTGAGCATGCACGACAGGTCCCTCAAG
GTGGCCGCGGTAGTCGAGAGCCTGGAGAGGGAGATGGAACTGCTGTGCCTCACCGGCGTG
GAGGACCAGCTGCAGGCAGACGTGCGGCCCACGCTGGAGATGCTGCGCAACGCCGGGATC
AAGATATGGATGCTAACAGGCGATAAACTCGAGACAGCTACCTGCATTGCCAAAAGTTCA
CATCTCGTGTCTAGAACACAAGATATTCATATTTTCAGACAGGTAACCAGTCGGGGAGAG
GCACATTTGGAGCTGAATGCATTTCGAAGGAAGCATGATTGTGCACTAGTCATATCTGGG
GACTCTCTGGAGGTTTGTCTAAAGTACTACGAGCATGAATTTGTGGAGCTGGCCTGCCAG
TGCCCTGCCGTGGTTTGCTGCCGCTGCTCACCCACCCAGAAGGCCCGCATTGTGACACTG
CTGCAGCAGCACACAGGGAGACGCACCTGCGCCATCGGTGATGGAGGAAATGATGTCAGC
ATGATTCAGGCAGCAGACTGTGGGATTGGGATTGAGGGAAAGGAGGGTAAACAGGCCTCG
CTGGCGGCCGACTTCTCCATCACGCAGTTCCGGCACATAGGCAGGCTGCTCATGGTGCAC
GGGCGGAACAGCTACAAGAGGTCGGCGGCACTCGGCCAGTTCGTCATGCACAGGGGCCTT
ATCATCTCCACCATGCAGGCTGTGTTTTCCTCAGTCTTCTACTTCGCATCCGTCCCTTTG
TATCAGGGCTTCCTCATGGTGGGGTATGCCACCATATACACCATGTTCCCAGTGTTCTCC
TTAGTGCTGGACCAGGACGTGAAGCCAGAGATGGCGATGCTCTACCCGGAGCTGTACAAG
GACCTCACCAAGGGAAGATCCTTGTCCTTCAAAACCTTCCTCATCTGGGTTTTAATAAGT
ATTTACCAAGGCGGCATCCTCATGTATGGGGCCCTGGTGCTCTTCGAGTCTGAGTTCGTC
CACGTGGTGGCCATCTCCTTCACCGCACTGATCCTGACCGAGCTGCTGATGGTGGCGCTG
ACCGTCCGCACGTGGCACTGGCTGATGGTGGTGGCCGAGTTCCTCAGCTTAGGCTGCTAC
GTGTCCTCACTCGCTTTTCTCAATGAATATTTTGGTATAGGCAGAGTGTCTTTTGGAGCT
TTCTTAGATGTTGCCTTTATCACCACCGTGACCTTCCTGTGGAAAGTGTCGGCGATCACC
GTGGTCAGCTGCCTCCCGCTGTATGTCCTCAAGTACCTGAGGCGCAAGCTCTCTCCTCCC
AGCTACTGCAAGCTGGCCTCCTAA

Protein Properties

Number of Residues

1147

Molecular Weight

129302.4

Theoretical pI

7.64

Pfam Domain Function

Hydrolase (PF00702 )
E1-E2_ATPase (PF00122 )

Signals

["None"]

Transmembrane Regions

["147-168", "174-196", "381-401", "410-431", "931-951", "964-982", "1013-1031", "1039-1061", "1068-1088", "1106-1130"]

Protein Sequence

>Probable phospholipid-transporting ATPase IIB
MADQIPLYPVRSAAAAAANRKRAAYYSAAGPRPGADRHSRYQLEDESAHLDEMPLMMSEE
GFENEESDYHTLPRARIMQRKRGLEWFVCDGWKFLCTSCCGWLINICRRKKELKARTVWL
GCPEKCEEKHPRNSIKNQKYNVFTFIPGVLYEQFKFFLNLYFLVISCSQFVPALKIGYLY
TYWAPLGFVLAVTMTREAIDEFRRFQRDKEVNSQLYSKLTVRGKVQVKSSDIQVGDLIIV
EKNQRIPSDMVFLRTSEKAGSCFIRTDQLDGETDWKLKVAVSCTQQLPALGDLFSISAYV
YAQKPQMDIHSFEGTFTREDSDPPIHESLSIENTLWASTIVASGTVIGVVIYTGKETRSV
MNTSNPKNKVGLLDLELNRLTKALFLALVALSIVMVTLQGFVGPWYRNLFRFLLLFSYII
PISLRVNLDMGKAVYGWMMMKDENIPGTVVRTSTIPEELGRLVYLLTDKTGTLTQNEMIF
KRLHLGTVSYGADTMDEIQSHVRDSYSQMQSQAGGNNTGSTPLRKAQSSAPKVRKSVSSR
IHEAVKAIVLCHNVTPVYESRAGVTEETEFAEADQDFSDENRTYQASSPDEVALVQWTES
VGLTLVSRDLTSMQLKTPSGQVLSFCILQLFPFTSESKRMGVIVRDESTAEITFYMKGAD
VAMSPIVQYNDWLEEECGNMAREGLRTLVVAKKALTEEQYQDFESRYTQAKLSMHDRSLK
VAAVVESLEREMELLCLTGVEDQLQADVRPTLEMLRNAGIKIWMLTGDKLETATCIAKSS
HLVSRTQDIHIFRQVTSRGEAHLELNAFRRKHDCALVISGDSLEVCLKYYEHEFVELACQ
CPAVVCCRCSPTQKARIVTLLQQHTGRRTCAIGDGGNDVSMIQAADCGIGIEGKEGKQAS
LAADFSITQFRHIGRLLMVHGRNSYKRSAALGQFVMHRGLIISTMQAVFSSVFYFASVPL
YQGFLMVGYATIYTMFPVFSLVLDQDVKPEMAMLYPELYKDLTKGRSLSFKTFLIWVLIS
IYQGGILMYGALVLFESEFVHVVAISFTALILTELLMVALTVRTWHWLMVVAEFLSLGCY
VSSLAFLNEYFGIGRVSFGAFLDVAFITTVTFLWKVSAITVVSCLPLYVLKYLRRKLSPP
SYCKLAS

External Links

GenBank ID Protein

41327760

UniProtKB/Swiss-Prot ID

O43861

UniProtKB/Swiss-Prot Entry Name

ATP9B_HUMAN

PDB IDs

Not Available

GenBank Gene ID

NM_198531.3

GeneCard ID