| Identification |
| HMDB Protein ID
| CDBP01340 |
| Secondary Accession Numbers
| Not Available |
| Name
| Potassium-transporting ATPase subunit beta |
| Description
| Not Available |
| Synonyms
|
- Gastric H(+)/K(+) ATPase subunit beta
- Proton pump beta chain
|
| Gene Name
| ATP4B |
| Protein Type
| Enzyme |
| Biological Properties |
| General Function
| Involved in sodium:potassium-exchanging ATPase activity |
| Specific Function
| Not Available |
| GO Classification
|
| Component |
| membrane |
| cell part |
| Function |
| potassium ion transmembrane transporter activity |
| potassium-transporting atpase activity |
| sodium:potassium-exchanging atpase activity |
| transmembrane transporter activity |
| substrate-specific transmembrane transporter activity |
| ion transmembrane transporter activity |
| cation transmembrane transporter activity |
| inorganic cation transmembrane transporter activity |
| monovalent inorganic cation transmembrane transporter activity |
| transporter activity |
| Process |
| metabolic process |
| nitrogen compound metabolic process |
| cellular nitrogen compound metabolic process |
| nucleobase, nucleoside, nucleotide and nucleic acid metabolic process |
| nucleobase, nucleoside and nucleotide metabolic process |
| nucleoside phosphate metabolic process |
| nucleotide metabolic process |
| sodium ion transport |
| establishment of localization |
| transport |
| monovalent inorganic cation transport |
| potassium ion transport |
| purine nucleotide metabolic process |
| ion transport |
| purine nucleotide biosynthetic process |
| atp biosynthetic process |
| purine nucleoside triphosphate biosynthetic process |
| cation transport |
| purine ribonucleoside triphosphate biosynthetic process |
|
| Cellular Location
|
- Membrane
- Single-pass type II membrane protein
|
| Pathways
|
| Name | SMPDB/Pathwhiz | KEGG | | Gastric Acid Production |    | Not Available | | Esomeprazole Action Pathway |    | Not Available | | Omeprazole Action Pathway |    | Not Available | | Lansoprazole Action Pathway |    | Not Available | | Pantoprazole Action Pathway |    | Not Available |
|
| Gene Properties |
| Chromosome Location
| Chromosome:1 |
| Locus
| 13q34 |
| SNPs
| ATP4B |
| Gene Sequence
|
>876 bp
ATGGCGGCTCTGCAGGAGAAGAAGACGTGTGGCCAGCGCATGGAGGAGTTCCAGCGTTAC
TGCTGGAACCCGGACACGGGGCAGATGCTGGGCCGCACCCTGTCCCGGTGGGTGTGGATC
AGCCTGTACTACGTGGCCTTCTACGTGGTGATGACTGGGCTCTTCGCCCTGTGCCTCTAT
GTGCTGATGCAGACAGTGGACCCGTACACACCGGACTACCAAGACCAGCTACGGTCACCA
GGGGTAACCTTAAGGCCGGATGTTTACGGGGAGAAAGGCCTGGAAATTGTCTACAACGTC
TCTGATAACAGAACCTGGGCAGACCTCACACAGACTCTCCACGCCTTCCTAGCAGGCTAC
TCTCCAGCAGCCCAGGAGGACAGCATCAACTGCACCTCCGAGCAGTACTTCTTCCAGGAG
AGTTTCCGCGCTCCCAACCACACCAAGTTCTCCTGCAAGTTCACGGCAGATATGCTGCAG
AACTGCTCAGGCCTGGCGGATCCCAACTTCGGCTTTGAAGAAGGAAAGCCATGTTTTATT
ATTAAAATGAACAGGATCGTCAAGTTCCTCCCCAGCAACGGCTCGGCCCCCAGAGTGGAC
TGCGCCTTCCTGGACCAGCCCCGCGAGCTCGGCCAGCCGCTGCAGGTCAAGTACTACCCT
CCCAACGGCACCTTCAGTCTGCACTACTTCCCTTATTACGGGAAGAAAGCCCAGCCCCAC
TACAGCAACCCCCTGGTGGCAGCGAAGCTCCTCAACATCCCCAGGAACGCTGAGGTCGCC
ATCGTGTGCAAGGTCATGGCGGAGCACGTGACCTTCAACAATCCCCACGACCCGTATGAA
GGGAAAGTGGAGTTCAAACTCAAGATTGAGAAGTGA
|
| Protein Properties |
| Number of Residues
| 291 |
| Molecular Weight
| 33367.0 |
| Theoretical pI
| 7.37 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Potassium-transporting ATPase subunit beta
MAALQEKKTCGQRMEEFQRYCWNPDTGQMLGRTLSRWVWISLYYVAFYVVMTGLFALCLY
VLMQTVDPYTPDYQDQLRSPGVTLRPDVYGEKGLEIVYNVSDNRTWADLTQTLHAFLAGY
SPAAQEDSINCTSEQYFFQESFRAPNHTKFSCKFTADMLQNCSGLADPNFGFEEGKPCFI
IKMNRIVKFLPSNGSAPRVDCAFLDQPRELGQPLQVKYYPPNGTFSLHYFPYYGKKAQPH
YSNPLVAAKLLNIPRNAEVAIVCKVMAEHVTFNNPHDPYEGKVEFKLKIEK
|
| External Links |
| GenBank ID Protein
| 4557339 |
| UniProtKB/Swiss-Prot ID
| P51164 |
| UniProtKB/Swiss-Prot Entry Name
| ATP4B_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_000705.3 |
| GeneCard ID
| ATP4B |
| GenAtlas ID
| ATP4B |
| HGNC ID
| HGNC:820 |
| References |
| General References
| Not Available |