| Identification |
| HMDB Protein ID
| CDBP01338 |
| Secondary Accession Numbers
| Not Available |
| Name
| Cyclin-dependent kinase-like 1 |
| Description
| Not Available |
| Synonyms
|
- Protein kinase p42 KKIALRE
- Serine/threonine-protein kinase KKIALRE
|
| Gene Name
| CDKL1 |
| Protein Type
| Enzyme |
| Biological Properties |
| General Function
| Involved in protein kinase activity |
| Specific Function
| ATP + a protein = ADP + a phosphoprotein |
| GO Classification
|
| Function |
| transferase activity |
| transferase activity, transferring phosphorus-containing groups |
| kinase activity |
| nucleoside binding |
| purine nucleoside binding |
| adenyl nucleotide binding |
| adenyl ribonucleotide binding |
| atp binding |
| protein kinase activity |
| protein serine/threonine kinase activity |
| binding |
| catalytic activity |
| Process |
| phosphorus metabolic process |
| phosphate metabolic process |
| metabolic process |
| cellular metabolic process |
| protein amino acid phosphorylation |
| phosphorylation |
|
| Cellular Location
|
- Nucleus
- Cytoplasm
|
| Pathways
|
Not Available
|
| Gene Properties |
| Chromosome Location
| Chromosome:1 |
| Locus
| 14q21.3 |
| SNPs
| CDKL1 |
| Gene Sequence
|
>1077 bp
ATGATGGAGAAGTATGAAAAAATTGGGAAAATTGGAGAAGGATCCTATGGAGTTGTTTTC
AAATGTAGAAACAGGGACACGGGTCAGATTGTGGCCATCAAGAAGTTTCTGGAATCAGAA
GATGACCCTGTCATAAAGAAAATTGCCCTTCGGGAAATCCGAATGCTCAAGCAACTCAAG
CATCCCAACCTTGTTAACCTCCTGGAAGTCTTCAGGAGGAAACGGAGGCTTCACCTGGTG
TTTGAATATTGTGACCACACAGTTCTCCATGAGTTGGACAGATACCAAAGAGGGGTACCA
GAACATCTCGTGAAGAGCATAACTTGGCAGACACTGCAAGCTGTAAATTTTTGCCATAAA
CACAATTGCATACATAGAGACGTGAAGCCAGAAAATATCCTCATCACGAAACATTCCGTG
ATTAAGCTTTGTGACTTTGGATTTGCTCGGCTTTTGACTGGACCGAGTGACTACTATACA
GACTACGTGGCTACCAGGTGGTACCGCTCCCCTGAGCTGCTGGTGGGGGACACGCAGTAC
GGCCCCCCGGTGGATGTTTGGGCAATTGGCTGTGTCTTTGCTGAGCTGCTGTCAGGAGTG
CCTCTGTGGCCAGGAAAATCGGATGTGGATCAGCTGTATCTGATTAGGAAGACCTTGGGG
GATCTCATTCCTAGGCACCAGCAAGTGTTTAGCACGAATCAGTACTTCAGTGGAGTGAAA
ATTCCAGACCCTGAAGATATGGAACCACTTGAATTAAAATTCCCAAACATCTCTTATCCT
GCCCTGGGGCTCCTAAAGGGCTGTCTCCACATGGACCCTACTCAAAGGCTGACATGTGAA
CAGCTGTTGCATCACCCATATTTTGAAAACATCAGAGAAATAGAGGATTTGGCAAAAGAA
CACAACAAACCAACAAGGAAGACCCTAAGAAAGAGCCGAAAGCACCACTGCTTTACAGAA
ACATCCAAGTTGCAGTACCTACCCCAGCTAACTGGCAGCAGCATCCTTCCAGCTTTGGAT
AATAAGAAGTACTACTGTGATACCAAGAAACTTAACTACCGTTTTCCAAACATTTAA
|
| Protein Properties |
| Number of Residues
| 357 |
| Molecular Weight
| 41671.0 |
| Theoretical pI
| 9.11 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Cyclin-dependent kinase-like 1
MEKYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKKFLESEDDPVIKKIALREIRMLKQLKH
PNLVNLLEVFRRKRRLHLVFEYCDHTVLHELDRYQRGVPEHLVKSITWQTLQAVNFCHKH
NCIHRDVKPENILITKHSVIKLCDFGFARLLAGPSDYYTDYVATRWYRSPELLVGDTQYG
PPVDVWAIGCVFAELLSGVPLWPGKSDVDQLYLIRKTLGDLIPRHQQVFSTNQYFSGVKI
PDPEDMEPLELKFPNISYPALGLLKGCLHMDPTQRLTCEQLLHHPYFENIREIEDLAKEH
NKPTRKTLRKSRKHHCFTETSKLQYLPQLTGSSILPALDNKKYYCDTKKLNYRFPNI
|
| External Links |
| GenBank ID Protein
| 37596297 |
| UniProtKB/Swiss-Prot ID
| Q00532 |
| UniProtKB/Swiss-Prot Entry Name
| CDKL1_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| Not Available |
| GeneCard ID
| CDKL1 |
| GenAtlas ID
| CDKL1 |
| HGNC ID
| HGNC:1781 |
| References |
| General References
| Not Available |