| Identification |
| HMDB Protein ID
| CDBP01300 |
| Secondary Accession Numbers
| Not Available |
| Name
| Phosphorylase b kinase gamma catalytic chain, testis/liver isoform |
| Description
| Not Available |
| Synonyms
|
- PHK-gamma-T
- PSK-C3
- Phosphorylase kinase subunit gamma-2
|
| Gene Name
| PHKG2 |
| Protein Type
| Enzyme |
| Biological Properties |
| General Function
| Involved in phosphorylase kinase activity |
| Specific Function
| Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. This isozyme may regulate glycogeneolysis in the testis |
| GO Classification
|
| Component |
| phosphorylase kinase complex |
| macromolecular complex |
| protein complex |
| Function |
| adenyl nucleotide binding |
| adenyl ribonucleotide binding |
| atp binding |
| phosphorylase kinase activity |
| calmodulin binding |
| protein binding |
| protein kinase activity |
| protein serine/threonine kinase activity |
| calmodulin-dependent protein kinase activity |
| binding |
| catalytic activity |
| transferase activity |
| transferase activity, transferring phosphorus-containing groups |
| kinase activity |
| nucleoside binding |
| purine nucleoside binding |
| Process |
| alcohol metabolic process |
| monosaccharide metabolic process |
| hexose metabolic process |
| glucose metabolic process |
| protein amino acid phosphorylation |
| phosphorylation |
| phosphorus metabolic process |
| phosphate metabolic process |
| metabolic process |
| cellular metabolic process |
| glycogen metabolic process |
| glycogen biosynthetic process |
| small molecule metabolic process |
|
| Cellular Location
|
Not Available
|
| Pathways
|
Not Available
|
| Gene Properties |
| Chromosome Location
| Chromosome:1 |
| Locus
| 16p11.2 |
| SNPs
| PHKG2 |
| Gene Sequence
|
>1221 bp
ATGACGCTGGACGTGGGGCCGGAGGATGAGCTGCCCGACTGGGCCGCCGCCAAAGAGTTT
TACCAGAAGTACGACCCTAAGGACGTCATCGGCAGAGGAGTGAGCTCTGTGGTCCGCCGT
TGTGTTCATCGAGCTACTGGCCACGAGTTTGCGGTGAAGATTATGGAAGTGACAGCTGAG
CGGCTGAGTCCTGAGCAGCTGGAGGAGGTGCGGGAAGCCACACGGCGAGAGACACACATC
CTTCGCCAGGTCGCCGGCCACCCCCACATCATCACCCTCATCGATTCCTACGAGTCTTCT
AGCTTCATGTTCCTGGTGTTTGACCTGATGCGGAAGGGAGAGCTGTTTGACTATCTCACA
GAGAAGGTGGCCCTCTCTGAAAAGGAAACCAGGTCCATCATGCGGTCTCTGCTGGAAGCA
GTGAGCTTTCTCCATGCCAACAACATTGTGCATCGAGATCTGAAGCCCGAGAATATTCTC
CTAGATGACAATATGCAGATCCGACTTTCAGATTTCGGGTTCTCCTGCCACTTGGAACCT
GGCGAGAAGCTTCGAGAGTTGTGTGGGACCCCAGGGTATCTAGCGCCAGAGATCCTTAAA
TGCTCCATGGATGAAACCCACCCAGGCTATGGCAAGGAGGTCGACCTCTGGGCCTGTGGG
GTGATCTTGTTCACACTCCTGGCTGGCTCGCCACCCTTCTGGCACCGGCGGCAGATCCTG
ATGTTACGCATGATCATGGAGGGCCAGTACCAGTTCAGTTCCCCCGAGTGGGATGACCGT
TCCAGCACTGTCAAAGACCTGATCTCCAGGCTGCTGCAGGTGGATCCTGAGGCACGCCTG
ACAGCTGAGCAGGCCCTACAGCACCCCTTCTTTGAGCGTTGTGAAGGCAGCCAACCCTGG
AACCTCACCCCCCGCCAGCGGTTCCGGGTGGCAGTGTGGACAGTGCTGGCTGCTGGACGA
GTGGCCCTAAGCACCCATCGTGTACGGCCACTGACCAAGAATGCACTGTTGAGGGACCCT
TATGCGCTGCGGTCAGTGCGGCACCTCATCGACAACTGTGCCTTCCGGCTCTACGGGCAC
TGGGTAAAGAAAGGGGAGCAGCAGAACCGGGCGGCTCTCTTTCAGCACCGGCCCCCTGGG
CCTTTTCCCATCATGGGCCCTGAAGAGGAGGGAGACTCTGCTGCTATAACTGAGGATGAG
GCCGTGCTTGTGCTGGGCTAG
|
| Protein Properties |
| Number of Residues
| 406 |
| Molecular Weight
| 46441.8 |
| Theoretical pI
| 6.35 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Phosphorylase b kinase gamma catalytic chain, testis/liver isoform
MTLDVGPEDELPDWAAAKEFYQKYDPKDVIGRGVSSVVRRCVHRATGHEFAVKIMEVTAE
RLSPEQLEEVREATRRETHILRQVAGHPHIITLIDSYESSSFMFLVFDLMRKGELFDYLT
EKVALSEKETRSIMRSLLEAVSFLHANNIVHRDLKPENILLDDNMQIRLSDFGFSCHLEP
GEKLRELCGTPGYLAPEILKCSMDETHPGYGKEVDLWACGVILFTLLAGSPPFWHRRQIL
MLRMIMEGQYQFSSPEWDDRSSTVKDLISRLLQVDPEARLTAEQALQHPFFERCEGSQPW
NLTPRQRFRVAVWTVLAAGRVALSTHRVRPLTKNALLRDPYALRSVRHLIDNCAFRLYGH
WVKKGEQQNRAALFQHRPPGPFPIMGPEEEGDSAAITEDEAVLVLG
|
| External Links |
| GenBank ID Protein
| 12803435 |
| UniProtKB/Swiss-Prot ID
| P15735 |
| UniProtKB/Swiss-Prot Entry Name
| PHKG2_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BC002541 |
| GeneCard ID
| PHKG2 |
| GenAtlas ID
| PHKG2 |
| HGNC ID
| HGNC:8931 |
| References |
| General References
| Not Available |