| Identification |
|---|
| HMDB Protein ID
| CDBP01263 |
| Secondary Accession Numbers
| Not Available |
| Name
| Testis-specific serine/threonine-protein kinase 4 |
| Description
| Not Available |
| Synonyms
|
- Serine/threonine-protein kinase 22E
- TSK-4
- TSSK-4
- Testis-specific kinase 4
|
| Gene Name
| TSSK4 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in protein kinase activity |
| Specific Function
| May be involved in a signaling pathway during male germ cell development or mature sperm function. Phosphorylates CREB1 on Ser-133 and stimulates downstream signaling |
| GO Classification
|
| Function |
| kinase activity |
| nucleoside binding |
| purine nucleoside binding |
| adenyl nucleotide binding |
| adenyl ribonucleotide binding |
| atp binding |
| magnesium ion binding |
| protein kinase activity |
| protein serine/threonine kinase activity |
| ion binding |
| cation binding |
| metal ion binding |
| binding |
| catalytic activity |
| transferase activity |
| transferase activity, transferring phosphorus-containing groups |
| Process |
| protein amino acid phosphorylation |
| phosphorylation |
| phosphorus metabolic process |
| phosphate metabolic process |
| metabolic process |
| cellular process |
| cellular metabolic process |
| cellular developmental process |
| cell differentiation |
|
| Cellular Location
|
Not Available
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 14q12 |
| SNPs
| TSSK4 |
| Gene Sequence
|
>987 bp
ATGGGGAAGGGAGATGTCTTAGAGGCAGCACCAACCACCACAGCCTACCATTCCCTCATG
GATGAATATGGTTATGAGGTGGGCAAGGCCATTGGCCATGGCTCCTATGGGTCGGTATAT
GAGGCTTTCTACACAAAGCAGAAGGTTATGGTGGCAGTCAAGATCATCTCAAAGAAGAAG
GCCTCTGATGACTATCTTAACAAGTTCCTGCCCCGTGAAATACAGGTAATGAAAGTCTTG
CGGCACAAGTACCTCATCAACTTCTATCGGGCCATTGAGAGCACATCTCGAGTATACATC
ATTCTGGAACTGGCTCAGGGTGGTGATGTCCTTGAATGGATCCAGCGCTACGGGGCCTGC
TCTGAGCCCCTTGCTGGCAAGTGGTTCTCCCAGCTGACCCTGGGCATTGCCTACCTGCAC
AGCAAGAGCATCGTGCACCGGGACTTAAAGTTGGAGAACCTGTTGCTGGACAAGTGGGAG
AATGTGAAGATATCAGACTTTGGCTTTGCCAAGATGGTGCCTTCTAACCAGCCTGTGGGT
TGTAGCCCTTCTTACCGCCAAGTGAACTGCTTTTCCCACCTCAGCCAGACTTACTGTGGC
AGCTTTGCTTACGCTTGCCCAGAGATCTTACGAGGCTTGCCCTACAACCCTTTCCTGTCT
GACACCTGGAGCATGGGCGTCATCCTTTACACTCTAGTGGTCGCCCATCTGCCCTTTGAT
GACACCAATCTCAAAAAGCTGCTAAGAGAGACTCAGAAGGAGGTCACTTTCCCAGCTAAC
CATACCATCTCCCAGGAGTGCAAGAACCTGATCCTCCAGATGCTACGCCAAGCCACTAAG
CGTGCCACCATTCTGGACATCATCAAGGATTCCTGGGTGCTCAAGTTCCAGCCTGAGCAA
CCCACCCATGAGATCAGGCTGCTTGAGGCCATGTGCCAGCTCCACAACACCACTAAACAG
CACCAATCCTTGCAAATTACGACCTGA
|
| Protein Properties |
|---|
| Number of Residues
| 328 |
| Molecular Weight
| 37454.1 |
| Theoretical pI
| 8.76 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Testis-specific serine/threonine-protein kinase 4
MGKGDVLEAAPTTTAYHSLMDEYGYEVGKAIGHGSYGSVYEAFYTKQKVMVAVKIISKKK
ASDDYLNKFLPREIQVMKVLRHKYLINFYRAIESTSRVYIILELAQGGDVLEWIQRYGAC
SEPLAGKWFSQLTLGIAYLHSKSIVHRDLKLENLLLDKWENVKISDFGFAKMVPSNQPVG
CSPSYRQVNCFSHLSQTYCGSFAYACPEILRGLPYNPFLSDTWSMGVILYTLVVAHLPFD
DTNLKKLLRETQKEVTFPANHTISQECKNLILQMLRQATKRATILDIIKDSWVLKFQPEQ
PTHEIRLLEAMCQLHNTTKQHQSLQITT
|
| External Links |
|---|
| GenBank ID Protein
| 42734401 |
| UniProtKB/Swiss-Prot ID
| Q6SA08 |
| UniProtKB/Swiss-Prot Entry Name
| TSSK4_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_174944.3 |
| GeneCard ID
| TSSK4 |
| GenAtlas ID
| TSSK4 |
| HGNC ID
| HGNC:19825 |
| References |
|---|
| General References
| Not Available |