| Identification |
|---|
| HMDB Protein ID
| CDBP01241 |
| Secondary Accession Numbers
| Not Available |
| Name
| Ephrin type-A receptor 7 |
| Description
| Not Available |
| Synonyms
|
- EHK-3
- EK11
- EPH homology kinase 3
- EPH-like kinase 11
- hEK11
|
| Gene Name
| EPHA7 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in ephrin receptor activity |
| Specific Function
| Receptor for members of the ephrin-A family. Binds to ephrin-A1, -A2, -A3, -A4 and -A5 |
| GO Classification
|
| Component |
| membrane part |
| intrinsic to membrane |
| integral to membrane |
| integral to plasma membrane |
| membrane |
| cell part |
| Function |
| protein binding |
| protein kinase activity |
| protein tyrosine kinase activity |
| transmembrane receptor protein tyrosine kinase activity |
| binding |
| catalytic activity |
| transferase activity |
| transferase activity, transferring phosphorus-containing groups |
| kinase activity |
| nucleoside binding |
| purine nucleoside binding |
| adenyl nucleotide binding |
| adenyl ribonucleotide binding |
| atp binding |
| ephrin receptor activity |
| Process |
| phosphorus metabolic process |
| phosphate metabolic process |
| enzyme linked receptor protein signaling pathway |
| transmembrane receptor protein tyrosine kinase signaling pathway |
| metabolic process |
| cellular metabolic process |
| protein amino acid phosphorylation |
| signaling |
| signaling pathway |
| cell surface receptor linked signaling pathway |
| phosphorylation |
|
| Cellular Location
|
- Membrane
- Single-pass type I membrane protein
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:6 |
| Locus
| 6q16.1 |
| SNPs
| EPHA7 |
| Gene Sequence
|
>2997 bp
ATGGTTTTTCAAACTCGGTACCCTTCATGGATTATTTTATGCTACATCTGGCTGCTCCGC
TTTGCACACACAGGGGAGGCGCAGGCTGCGAAGGAAGTACTACTGCTGGATTCTAAAGCA
CAACAAACAGAGTTGGAGTGGATTTCCTCTCCACCCAATGGGTGGGAAGAAATTAGTGGT
TTGGATGAGAACTATACCCCGATACGAACATACCAGGTGTGCCAAGTCATGGAGCCCAAC
CAAAACAACTGGCTGCGGACTAACTGGATTTCCAAAGGCAATGCACAAAGGATTTTTGTA
GAATTGAAATTCACCCTGAGGGATTGTAACAGTCTTCCTGGAGTACTGGGAACTTGCAAG
GAAACATTTAATTTGTACTATTATGAAACAGACTATGACACTGGCAGGAATATAAGAGAA
AACCTCTATGTAAAAATAGACACCATTGCTGCAGATGAAAGTTTTACCCAAGGTGACCTT
GGTGAAAGAAAGATGAAGCTTAACACTGAGGTGAGAGAGATTGGACCTTTGTCCAAAAAG
GGATTCTATCTTGCCTTTCAGGATGTAGGGGCTTGCATAGCTTTGGTTTCTGTCAAAGTG
TACTACAAGAAGTGCTGGTCCATTATTGAGAACTTAGCTATCTTTCCAGATACAGTGACT
GGTTCAGAATTTTCCTCTTTAGTCGAGGTTCGAGGGACATGTGTCAGCAGTGCAGAGGAA
GAAGCGGAAAACGCCCCCAGGATGCACTGCAGTGCAGAAGGAGAATGGTTAGTGCCCATT
GGAAAATGTATCTGCAAAGCAGGCTACCAGCAAAAAGGAGACACTTGTGAACCCTGTGGC
CGTGGGTTCTACAAGTCTTCCTCTCAAGATCTTCAGTGCTCTCGTTGTCCAACTCACAGT
TTTTCTGATAAAGAAGGCTCCTCCAGATGTGAATGTGAAGATGGGTATTACAGGGCTCCA
TCTGACCCACCATACGTTGCATGCACAAGGCCTCCATCTGCACCACAGAACCTCATTTTC
AACATCAACCAAACCACAGTAAGTTTGGAATGGAGTCCTCCTGCAGACAATGGGGGAAGA
AACGATGTGACCTACAGAATATTGTGTAAGCGGTGCAGTTGGGAGCAGGGCGAATGTGTT
CCCTGTGGGAGTAACATTGGATACATGCCCCAGCAGACTGGATTAGAGGATAACTATGTC
ACTGTCATGGACCTGCTAGCCCACGCTAATTATACTTTTGAAGTTGAAGCTGTAAATGGA
GTTTCTGACTTAAGCCGATCCCAGAGGCTCTTTGCTGCTGTCAGTATCACCACTGGTCAA
GCAGCTCCCTCGCAAGTGAGCGGAGTAATGAAGGAGAGAGTACTGCAGCGGAGTGTCGAG
CTTTCCTGGCAGGAACCAGAGCATCCCAATGGAGTCATCACAGAATATGAAATCAAGTAT
TACGAGAAAGATCAAAGGGAACGGACCTACTCAACAGTAAAAACCAAGTCTACTTCAGCC
TCCATTAATAATCTGAAACCAGGAACAGTGTATGTTTTCCAGATTCGGGCTTTTACTGCT
GCTGGTTATGGAAATTACAGTCCCAGACTTGATGTTGCTACACTAGAGGAAGCTACAGGT
AAAATGTTTGAAGCTACAGCTGTCTCCAGTGAACAGAATCCTGTTATTATCATTGCTGTG
GTTGCTGTAGCTGGGACCATCATTTTGGTGTTCATGGTCTTTGGCTTCATCATTGGGAGA
AGGCACTGTGGTTATAGCAAAGCTGACCAAGAAGGCGATGAAGAGCTTTACTTTCATTTT
AAATTTCCAGGCACCAAAACCTACATTGACCCTGAAACCTATGAGGACCCAAATAGAGCT
GTCCATCAATTCGCCAAGGAGCTAGATGCCTCCTGTATTAAAATTGAGCGTGTGATTGGT
GCAGGAGAATTCGGTGAAGTCTGCAGTGGCCGTTTGAAACTTCCAGGGAAAAGAGATGTT
GCAGTAGCCATAAAAACCCTGAAAGTTGGTTACACAGAAAAACAAAGGAGAGACTTTTTG
TGTGAAGCAAGCATCATGGGGCAGTTTGACCACCCAAATGTTGTCCATTTGGAAGGGGTT
GTTACAAGAGGGAAACCAGTCATGATAGTAATAGAGTTCATGGAAAATGGAGCCCTAGAT
GCATTTCTCAGGAAACATGATGGGCAATTTACAGTCATTCAGTTAGTAGGAATGCTGAGA
GGAATTGCTGCTGGAATGAGATATTTGGCTGATATGGGATATGTTCACAGGGACCTTGCA
GCTCGCAATATTCTTGTCAACAGCAATCTCGTTTGTAAAGTGTCAGATTTTGGCCTGTCC
CGAGTTATAGAGGATGATCCAGAAGCTGTCTATACAACTACTGGTGGAAAAATTCCAGTA
AGGTGGACAGCACCCGAAGCCATCCAGTACCGGAAATTCACATCAGCCAGTGATGTATGG
AGCTATGGAATAGTCATGTGGGAAGTTATGTCTTATGGAGAAAGACCTTATTGGGACATG
TCAAATCAAGATGTTATAAAAGCAATAGAAGAAGGTTATCGTTTACCAGCACCCATGGAC
TGCCCAGCTGGCCTTCACCAGCTAATGTTGGATTGTTGGCAAAAGGAGCGTGCTGAAAGG
CCAAAATTTGAACAGATAGTTGGAATTCTAGACAAAATGATTCGAAACCCAAATAGTCTG
AAAACTCCCCTGGGAACTTGTAGTAGGCCAATAAGCCCTCTTCTGGATCAAAACACTCCT
GATTTCACTACCTTTTGTTCAGTTGGAGAATGGCTACAAGCTATTAAGATGGAAAGATAT
AAAGATAATTTCACGGCAGCTGGCTACAATTCCCTTGAATCAGTAGCCAGGATGACTATT
GAGGATGTGATGAGTTTAGGGATCACACTGGTTGGTCATCAAAAGAAAATCATGAGCAGC
ATTCAGACTATGAGAGCACAAATGCTACATTTACATGGAACTGGCATTCAAGTGTGA
|
| Protein Properties |
|---|
| Number of Residues
| 998 |
| Molecular Weight
| 112095.8 |
| Theoretical pI
| 5.55 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Ephrin type-A receptor 7
MVFQTRYPSWIILCYIWLLRFAHTGEAQAAKEVLLLDSKAQQTELEWISSPPNGWEEISG
LDENYTPIRTYQVCQVMEPNQNNWLRTNWISKGNAQRIFVELKFTLRDCNSLPGVLGTCK
ETFNLYYYETDYDTGRNIRENLYVKIDTIAADESFTQGDLGERKMKLNTEVREIGPLSKK
GFYLAFQDVGACIALVSVKVYYKKCWSIIENLAIFPDTVTGSEFSSLVEVRGTCVSSAEE
EAENAPRMHCSAEGEWLVPIGKCICKAGYQQKGDTCEPCGRGFYKSSSQDLQCSRCPTHS
FSDKEGSSRCECEDGYYRAPSDPPYVACTRPPSAPQNLIFNINQTTVSLEWSPPADNGGR
NDVTYRILCKRCSWEQGECVPCGSNIGYMPQQTGLEDNYVTVMDLLAHANYTFEVEAVNG
VSDLSRSQRLFAAVSITTGQAAPSQVSGVMKERVLQRSVELSWQEPEHPNGVITEYEIKY
YEKDQRERTYSTVKTKSTSASINNLKPGTVYVFQIRAFTAAGYGNYSPRLDVATLEEATG
KMFEATAVSSEQNPVIIIAVVAVAGTIILVFMVFGFIIGRRHCGYSKADQEGDEELYFHF
KFPGTKTYIDPETYEDPNRAVHQFAKELDASCIKIERVIGAGEFGEVCSGRLKLPGKRDV
AVAIKTLKVGYTEKQRRDFLCEASIMGQFDHPNVVHLEGVVTRGKPVMIVIEFMENGALD
AFLRKHDGQFTVIQLVGMLRGIAAGMRYLADMGYVHRDLAARNILVNSNLVCKVSDFGLS
RVIEDDPEAVYTTTGGKIPVRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDM
SNQDVIKAIEEGYRLPAPMDCPAGLHQLMLDCWQKERAERPKFEQIVGILDKMIRNPNSL
KTPLGTCSRPISPLLDQNTPDFTTFCSVGEWLQAIKMERYKDNFTAAGYNSLESVARMTI
EDVMSLGITLVGHQKKIMSSIQTMRAQMLHLHGTGIQV
|
| External Links |
|---|
| GenBank ID Protein
| Not Available |
| UniProtKB/Swiss-Prot ID
| Q15375 |
| UniProtKB/Swiss-Prot Entry Name
| EPHA7_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| L36642 |
| GeneCard ID
| EPHA7 |
| GenAtlas ID
| EPHA7 |
| HGNC ID
| HGNC:3390 |
| References |
|---|
| General References
| Not Available |