| Identification |
|---|
| HMDB Protein ID
| CDBP01217 |
| Secondary Accession Numbers
| Not Available |
| Name
| Testis-specific serine/threonine-protein kinase 2 |
| Description
| Not Available |
| Synonyms
|
- DiGeorge syndrome protein G
- Serine/threonine-protein kinase 22B
- TSK-2
- TSSK-2
- Testis-specific kinase 2
|
| Gene Name
| TSSK2 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in protein kinase activity |
| Specific Function
| Involved in the late stages of spermatogenesis, during the reconstruction of the cytoplasm |
| GO Classification
|
| Function |
| magnesium ion binding |
| protein kinase activity |
| protein serine/threonine kinase activity |
| ion binding |
| cation binding |
| metal ion binding |
| binding |
| catalytic activity |
| transferase activity |
| transferase activity, transferring phosphorus-containing groups |
| kinase activity |
| nucleoside binding |
| purine nucleoside binding |
| adenyl nucleotide binding |
| adenyl ribonucleotide binding |
| atp binding |
| Process |
| phosphorus metabolic process |
| phosphate metabolic process |
| metabolic process |
| cellular process |
| cellular metabolic process |
| cellular developmental process |
| cell differentiation |
| protein amino acid phosphorylation |
| phosphorylation |
|
| Cellular Location
|
- Cytoplasm
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:2 |
| Locus
| 22q11.21 |
| SNPs
| TSSK2 |
| Gene Sequence
|
>1077 bp
ATGGACGATGCCACAGTCCTAAGGAAGAAGGGTTACATCGTAGGCATCAATCTTGGCAAG
GGTTCCTACGCAAAAGTCAAATCTGCCTACTCTGAGCGCCTCAAGTTCAATGTGGCTGTC
AAGATCATCGACCGCAAGAAAACACCTACTGACTTTGTGGAGAGATTCCTTCCTCGGGAG
ATGGACATCCTGGCAACTGTCAACCACGGCTCCATCATCAAGACTTACGAGATCTTTGAG
ACCTCTGACGGACGGATCTACATCATCATGGAGCTTGGCGTCCAGGGCGACCTCCTCGAG
TTCATCAAGTGCCAGGGAGCCCTGCATGAGGACGTGGCACGCAAGATGTTCCGACAGCTC
TCCTCCGCCGTCAAGTACTGCCACGACCTGGACATCGTCCACCGGGACCTCAAGTGCGAG
AACCTTCTCCTCGACAAGGACTTCAACATCAAGCTGTCTGACTTTGGCTTCTCCAAGCGC
TGCCTGCGGGACAGCAATGGGCGCATCATCCTCAGCAAGACCTTCTGCGGGTCGGCAGCA
TATGCAGCCCCCGAGGTGCTGCAGAGCATCCCCTACCAGCCCAAGGTGTATGACATCTGG
AGCCTGGGCGTGATCCTGTACATCATGGTCTGCGGCTCCATGCCCTATGACGACTCCGAC
ATCAGGAAGATGCTGCGTATCCAGAAGGAGCACCGTGTGGACTTCCCGCGCTCCAAGAAC
CTGACCTGCGAGTGCAAGGACCTCATCTACCGCATGCTGCAGCCCGACGTCAGCCAGCGG
CTCCACATCGATGAGATCCTCAGCCACTCGTGGCTGCAGCCCCCCAAGCCCAAGCCAACG
TCTTCTGCTTCCTTCAAGAGGGAGGGGGAGGGCAAGTACCGCGCTGAGTGCAAACTGGAC
ACCAAGACAGGCTTGAGGCCCGACCACCGGCCCGACCACAAGCTTGGAGCCAAAACCCAG
CACCGGCTGCTGGTGGTGCCCGAGAACGAGAACAGGATGGAGGACAGGCTGGCCGAGACC
TCCAGGGCCAAAGACCATCACATCTCCGGAGCTGAGGTGGGGAAAGCAAGCACCTAG
|
| Protein Properties |
|---|
| Number of Residues
| 358 |
| Molecular Weight
| 40938.8 |
| Theoretical pI
| 9.13 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Testis-specific serine/threonine-protein kinase 2
MDDATVLRKKGYIVGINLGKGSYAKVKSAYSERLKFNVAVKIIDRKKTPTDFVERFLPRE
MDILATVNHGSIIKTYEIFETSDGRIYIIMELGVQGDLLEFIKCQGALHEDVARKMFRQL
SSAVKYCHDLDIVHRDLKCENLLLDKDFNIKLSDFGFSKRCLRDSNGRIILSKTFCGSAA
YAAPEVLQSIPYQPKVYDIWSLGVILYIMVCGSMPYDDSDIRKMLRIQKEHRVDFPRSKN
LTCECKDLIYRMLQPDVSQRLHIDEILSHSWLQPPKPKATSSASFKREGEGKYRAECKLD
TKTGLRPDHRPDHKLGAKTQHRLLVVPENENRMEDRLAETSRAKDHHISGAEVGKAST
|
| External Links |
|---|
| GenBank ID Protein
| 15430703 |
| UniProtKB/Swiss-Prot ID
| Q96PF2 |
| UniProtKB/Swiss-Prot Entry Name
| TSSK2_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AF362953 |
| GeneCard ID
| TSSK2 |
| GenAtlas ID
| TSSK2 |
| HGNC ID
| HGNC:11401 |
| References |
|---|
| General References
| Not Available |