| Identification |
| HMDB Protein ID
| CDBP01165 |
| Secondary Accession Numbers
| Not Available |
| Name
| Hormonally up-regulated neu tumor-associated kinase |
| Description
| Not Available |
| Synonyms
|
- B19
- Serine/threonine-protein kinase MAK-V
|
| Gene Name
| HUNK |
| Protein Type
| Enzyme |
| Biological Properties |
| General Function
| Involved in protein serine/threonine kinase activity |
| Specific Function
| ATP + a protein = ADP + a phosphoprotein |
| GO Classification
|
| Function |
| atp binding |
| protein kinase activity |
| protein serine/threonine kinase activity |
| binding |
| catalytic activity |
| transferase activity |
| transferase activity, transferring phosphorus-containing groups |
| kinase activity |
| nucleoside binding |
| purine nucleoside binding |
| adenyl nucleotide binding |
| adenyl ribonucleotide binding |
| Process |
| phosphorus metabolic process |
| phosphate metabolic process |
| metabolic process |
| cellular metabolic process |
| protein amino acid phosphorylation |
| phosphorylation |
|
| Cellular Location
|
Not Available
|
| Pathways
|
Not Available
|
| Gene Properties |
| Chromosome Location
| Chromosome:2 |
| Locus
| 21q22.1 |
| SNPs
| HUNK |
| Gene Sequence
|
>2145 bp
ATGCCGGCGGCGGCGGGGGACGGGCTCCTGGGGGAGCCGGCGGCGCCTGGGGGCGGCGGC
GGCGCGGAGGACGCGGCCAGGCCCGCGGCGGCCTGCGAGGGAAGTTTCCTGCCTGCCTGG
GTGAGCGGCGTGCCCCGCGAGCGGCTCCGCGACTTCCAGCACCACAAGCGCGTGGGCAAC
TACCTCATCGGCAGCAGGAAGCTGGGCGAGGGCTCCTTTGCCAAGGTGCGCGAGGGGCTG
CACGTGCTGACCGGGGAGAAGGTGGCCATAAAAGTCATTGATAAGAAGAGAGCCAAAAAG
GACACCTATGTCACCAAAAACCTGCGGCGAGAGGGTCAGATCCAGCAGATGATCCGCCAC
CCCAATATCACTCAGCTCCTTGATATTTTAGAAACGGAAAACAGCTACTACCTGGTCATG
GAGCTGTGCCCTGGGGGCAACCTGATGCACAAGATCTATGAGAAGAAGCGGCTGGAGGAG
TCCGAAGCCCGCAGATACATCCGACAGCTCATCTCTGCCGTAGAGCACCTGCACCGGGCC
GGGGTGGTCCACAGAGACTTGAAGATAGAGAATTTGCTACTAGATGAAGACAATAATATC
AAGCTGATTGACTTTGGTTTGAGCAACTGCGCAGGGATCCTGGGTTACTCGGATCCGTTC
AGCACACAGTGTGGCAGCCCTGCCTACGCTGCACCTGAACTGCTCGCCAGGAAGAAATAC
GGCCCCAAAATCGATGTCTGGTCCATAGGTGTGAACATGTATGCCATGTTGACCGGGACG
CTGCCTTTCACGGTGGAGCCTTTCAGCCTGAGGGCTTTGTACCAGAAGATGGTAGACAAA
GAAATGAACCCCCTCCCCACTCAGCTCTCCACAGGTGCCATCAGTTTCCTGCGCTCTCTC
CTGGAACCGGATCCTGTGAAGAGGCCAAATATTCAGCAGGCACTGGCGAATCGCTGGCTT
AATGAGAATTACACGGGCAAAGTGCCCTGTAATGTCACCTATCCCAACAGGATTTCTCTG
GAAGATCTGAGCCCGAGCGTCGTGCTGCACATGACCGAGAAGCTGGGTTACAAGAACAGC
GACGTGATCAACACTGTGCTCTCCAACCGCGCCTGCCACATCCTGGCCATCTACTTCCTC
TTAAACAAGAAACTGGAGCGCTATTTGTCAGGGAAATCTGACATCCAGGACAGCCTCTGC
TACAAGACCCGGCTCTACCAGATAGAAAAGTACAGGGCCCCCAAGGAGTCCTATGAGGCC
TCTCTGGACACCTGGACACGAGATCTTGAATTCCATGCCGTGCAGGATAAAAAGCCCAAA
GAACAAGAAAAAAGAGGGGATTTTCTTCATCGACCATTCTCCAAGAAGTTGGACAAGAAC
CTGCCCTCGCACAAACAGCCCTCAGGCTCGCTTATGACACAGATTCAGAACACCAAAGCC
CTCCTGAAGGACCGGAAGGCCTCCAAGTCCAGCTTCCCCGACAAAGATTCCTTTGGCTGC
CGCAATATTTTCCGCAAAACCTCAGATTCCAATTGTGTGGCTTCTTCTTCCATGGAGTTC
ATCCCCGTGCCACCGCCCAGGACCCCGAGGATTGTGAAGAAACCGGAGCCCCATCAGCCA
GGGCCCGGAAGCACTGGCATCCCCCACAAGGAAGACCCCCTGATGCTGGACATGGTGCGC
TCCTTCGAGTCTGTGGATCGCGACGACCACGTAGAAGTGCTGTCTCCCTCTCATCACTAC
AGGATTCTGAACTCCCCGGTCAGCTTGGCTCGCAGAAATTCCAGCGAGAGGACGCTGTCC
CCGGGTCTGCCATCCGGAAGCATGTCGCCTCTCCATACTCCTTTGCATCCAACTCTGGTC
TCTTTTGCTCACGAAGATAAGAACAGCCCCCCAAAAGAGGAGGGCCTGTGTTGCCCACCT
CCGGTTCCCAGCAATGGCCCCATGCAGCCTCTGGGGAGCCCCAATTGTGTGAAAAGCCGA
GGCCGGTTCCCTATGATGGGCATCGGACAGATGTTAAGGAAGCGCCATCAGAGTCTGCAG
CCATCTGCAGATAGGCCCCTGGAGGCCAGCCTGCCCCCACTGCAGCCCCTAGCCCCTGTG
AACCTTGCCTTTGACATGGCCGATGGGGTCAAGACCCAGTGCTAA
|
| Protein Properties |
| Number of Residues
| 714 |
| Molecular Weight
| 79684.8 |
| Theoretical pI
| 9.54 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Hormonally up-regulated neu tumor-associated kinase
MPAAAGDGLLGEPAAPGGGGGAEDAARPAAACEGSFLPAWVSGVPRERLRDFQHHKRVGN
YLIGSRKLGEGSFAKVREGLHVLTGEKVAIKVIDKKRAKKDTYVTKNLRREGQIQQMIRH
PNITQLLDILETENSYYLVMELCPGGNLMHKIYEKKRLEESEARRYIRQLISAVEHLHRA
GVVHRDLKIENLLLDEDNNIKLIDFGLSNCAGILGYSDPFSTQCGSPAYAAPELLARKKY
GPKIDVWSIGVNMYAMLTGTLPFTVEPFSLRALYQKMVDKEMNPLPTQLSTGAISFLRSL
LEPDPVKRPNIQQALANRWLNENYTGKVPCNVTYPNRISLEDLSPSVVLHMTEKLGYKNS
DVINTVLSNRACHILAIYFLLNKKLERYLSGKSDIQDSLCYKTRLYQIEKYRAPKESYEA
SLDTWTRDLEFHAVQDKKPKEQEKRGDFLHRPFSKKLDKNLPSHKQPSGSLMTQIQNTKA
LLKDRKASKSSFPDKDSFGCRNIFRKTSDSNCVASSSMEFIPVPPPRTPRIVKKPEPHQP
GPGSTGIPHKEDPLMLDMVRSFESVDRDDHVEVLSPSHHYRILNSPVSLARRNSSERTLS
PGLPSGSMSPLHTPLHPTLVSFAHEDKNSPPKEEGLCCPPPVPSNGPMQPLGSPNCVKSR
GRFPMMGIGQMLRKRHQSLQPSADRPLEASLPPLQPLAPVNLAFDMADGVKTQC
|
| External Links |
| GenBank ID Protein
| 6850973 |
| UniProtKB/Swiss-Prot ID
| P57058 |
| UniProtKB/Swiss-Prot Entry Name
| HUNK_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AJ271722 |
| GeneCard ID
| HUNK |
| GenAtlas ID
| HUNK |
| HGNC ID
| HGNC:13326 |
| References |
| General References
| Not Available |