Cannabis Compound Database: Showing Protein Tyrosine-protein kinase receptor TYRO3 (CDBP01144)

Identification Biological properties Gene properties Protein properties External links References XML Show 2 compounds

Identification

HMDB Protein ID

CDBP01144

Secondary Accession Numbers

Not Available

Name

Tyrosine-protein kinase receptor TYRO3

Description

Not Available

Synonyms

Tyrosine-protein kinase DTK
Tyrosine-protein kinase RSE
Tyrosine-protein kinase SKY
Tyrosine-protein kinase byk

Gene Name

TYRO3

Protein Type

Enzyme

Biological Properties

General Function

Involved in protein kinase activity

Specific Function

May be involved in cell adhesion processes, particularly in the central nervous system. In case of filovirus infection, seems to function as a cell entry factor

GO Classification

Component
intrinsic to membrane
integral to membrane
cell part
membrane part
Function
protein tyrosine kinase activity
transmembrane receptor protein tyrosine kinase activity
binding
catalytic activity
transferase activity
transferase activity, transferring phosphorus-containing groups
kinase activity
nucleoside binding
purine nucleoside binding
adenyl nucleotide binding
adenyl ribonucleotide binding
atp binding
protein binding
protein kinase activity
Process
phosphorus metabolic process
phosphate metabolic process
cell adhesion
metabolic process
cellular process
cellular metabolic process
protein amino acid phosphorylation
phosphorylation

Cellular Location

Cell membrane
Single-pass type I membrane protein

Pathways

Not Available

Gene Properties

Chromosome Location

Chromosome:1

Locus

15q15

SNPs

TYRO3

Gene Sequence

>2673 bp
ATGGCGCTGAGGCGGAGCATGGGGCGGCCGGGGCTCCCGCCGCTGCCGCTGCCGCCGCCA
CCGCGGCTCGGGCTGCTGCTGGCGGCTCTGGCTTCTCTGCTGCTCCCGGAGTCCGCCGCC
GCAGGTCTGAAGCTCATGGGAGCCCCGGTGAAGCTGACAGTGTCTCAGGGGCAGCCGGTG
AAGCTCAACTGCAGTGTGGAGGGGATGGAGGAGCCTGACATCCAGTGGGTGAAGGATGGG
GCTGTGGTCCAGAACTTGGACCAGTTGTACATCCCAGTCAGCGAGCAGCACTGGATCGGC
TTCCTCAGCCTGAAGTCAGTGGAGCGCTCTGACGCCGGCCGGTACTGGTGCCAGGTGGAG
GATGGGGGTGAAACCGAGATCTCCCAGCCAGTGTGGCTCACGGTAGAAGGTGTGCCATTT
TTCACAGTGGAGCCAAAAGATCTGGCAGTGCCACCCAATGCCCCTTTCCAACTGTCTTGT
GAGGCTGTGGGTCCCCCTGAACCTGTTACCATTGTCTGGTGGAGAGGAACTACGAAGATC
GGGGGACCCGCTCCCTCTCCATCTGTTTTAAATGTAACAGGGGTGACCCAGAGCACCATG
TTTTCCTGTGAAGCTCACAACCTAAAAGGCCTGGCCTCTTCTCGCACAGCCACTGTTCAC
CTTCAAGCACTGCCTGCAGCCCCCTTCAACATCACCGTGACAAAGCTTTCCAGCAGCAAC
GCTAGTGTGGCCTGGATGCCAGGTGCTGATGGCCGAGCTCTGCTACAGTCCTGTACAGTT
CAGGTGACACAGGCCCCAGGAGGCTGGGAAGTCCTGGCTGTTGTGGTCCCTGTGCCCCCC
TTTACCTGCCTGCTCCGGGACCTGGTGCCTGCCACCAACTACAGCCTCAGGGTGCGCTGT
GCCAATGCCTTGGGGCCCTCTCCCTATGCTGACTGGGTGCCCTTTCAGACCAAGGGTCTA
GCCCCAGCCAGCGCTCCCCAAAACCTCCATGCCATCCGCACAGATTCAGGCCTCATCTTG
GAGTGGGAAGAAGTGATCCCCGAGGCCCCTTTGGAAGGCCCCCTGGGACCCTACAAACTG
TCCTGGGTTCAAGACAATGGAACCCAGGATGAGCTGACAGTGGAGGGGACCAGGGCCAAT
TTGACAGGCTGGGATCCCCAAAAGGACCTGATCGTACGTGTGTGCGTCTCCAATGCAGTT
GGCTGTGGACCCTGGAGTCAGCCACTGGTGGTCTCTTCTCATGACCGTGCAGGCCAGCAG
GGCCCTCCTCACAGCCGCACATCCTGGGTACCTGTGGTCCTTGGTGTGCTAACGGCCCTG
GTGACGGCTGCTGCCCTGGCCCTCATCCTGCTTCGAAAGAGACGGAAAGAGACGCGGTTT
GGGCAAGCCTTTGACAGTGTCATGGCCCGGGGAGAGCCAGCCGTTCACTTCCGGGCAGCC
CGGTCCTTCAATCGAGAAAGGCCCGAGCGCATCGAGGCCACATTGGACAGCTTGGGCATC
AGCGATGAACTAAAGGAAAAACTGGAGGATGTGCTCATCCCAGAGCAGCAGTTCACCCTG
GGCCGGATGTTGGGCAAAGGAGAGTTTGGTTCAGTGCGGGAGGCCCAGCTGAAGCAAGAG
GATGGCTCCTTTGTGAAAGTGGCTGTGAAGATGCTGAAAGCTGACATCATTGCCTCAAGC
GACATTGAAGAGTTCCTCAGGGAAGCAGCTTGCATGAAGGAGTTTGACCATCCACACGTG
GCCAAACTTGTTGGGGTAAGCCTCCGGAGCAGGGCTAAAGGCCGTCTCCCCATCCCCATG
GTCATCTTGCCCTTCATGAAGCATGGGGACCTGCATGCCTTCCTGCTCGCCTCCCGGATT
GGGGAGAACCCCTTTAACCTACCCCTCCAGACCCTGATCCGGTTCATGGTGGACATTGCC
TGCGGCATGGAGTACCTGAGCTCTCGGAACTTCATCCACCGAGACCTGGCTGCTCGGAAT
TGCATGCTGGCAGAGGACATGACAGTGTGTGTGGCTGACTTCGGACTCTCCCGGAAGATC
TACAGTGGGGACTACTATCGTCAAGGCTGTGCCTCCAAACTGCCTGTCAAGTGGCTGGCC
CTGGAGAGCCTGGCCGACAACCTGTATACTGTGCAGAGTGACGTGTGGGCGTTCGGGGTG
ACCATGTGGGAGATCATGACACGTGGGCAGACGCCATATGCTGGCATCGAAAACGCTGAG
ATTTACAACTACCTCATTGGCGGGAACCGCCTGAAACAGCCTCCGGAGTGTATGGAGGAC
GTGTATGATCTCATGTACCAGTGCTGGAGTGCTGACCCCAAGCAGCGCCCGAGCTTTACT
TGTCTGCGAATGGAACTGGAGAACATCTTGGGCCAGCTGTCTGTGCTATCTGCCAGCCAG
GACCCCTTATACATCAACATCGAGAGAGCTGAGGAGCCCACTGCGGGAGGCAGCCTGGAG
CTACCTGGCAGGGATCAGCCCTACAGTGGGGCTGGGGATGGCAGTGGCATGGGGGCAGTG
GGTGGCACTCCCAGTGACTGTCGGTACATACTCACCCCCGGAGGGCTGGCTGAGCAGCCA
GGGCAGGCAGAGCACCAGCCAGAGAGTCCCCTCAATGAGACACAGAGGCTTTTGCTGCTG
CAGCAAGGGCTACTGCCACACAGTAGCTGTTAG

Protein Properties

Number of Residues

890

Molecular Weight

96904.4

Theoretical pI

5.39

Pfam Domain Function

Pkinase_Tyr (PF07714 )
I-set (PF07679 )
fn3 (PF00041 )

Signals

["1-40"]

Transmembrane Regions

["430-450"]

Protein Sequence

>Tyrosine-protein kinase receptor TYRO3
MALRRSMGRPGLPPLPLPPPPRLGLLLAALASLLLPESAAAGLKLMGAPVKLTVSQGQPV
KLNCSVEGMEEPDIQWVKDGAVVQNLDQLYIPVSEQHWIGFLSLKSVERSDAGRYWCQVE
DGGETEISQPVWLTVEGVPFFTVEPKDLAVPPNAPFQLSCEAVGPPEPVTIVWWRGTTKI
GGPAPSPSVLNVTGVTQSTMFSCEAHNLKGLASSRTATVHLQALPAAPFNITVTKLSSSN
ASVAWMPGADGRALLQSCTVQVTQAPGGWEVLAVVVPVPPFTCLLRDLVPATNYSLRVRC
ANALGPSPYADWVPFQTKGLAPASAPQNLHAIRTDSGLILEWEEVIPEAPLEGPLGPYKL
SWVQDNGTQDELTVEGTRANLTGWDPQKDLIVRVCVSNAVGCGPWSQPLVVSSHDRAGQQ
GPPHSRTSWVPVVLGVLTALVTAAALALILLRKRRKETRFGQAFDSVMARGEPAVHFRAA
RSFNRERPERIEATLDSLGISDELKEKLEDVLIPEQQFTLGRMLGKGEFGSVREAQLKQE
DGSFVKVAVKMLKADIIASSDIEEFLREAACMKEFDHPHVAKLVGVSLRSRAKGRLPIPM
VILPFMKHGDLHAFLLASRIGENPFNLPLQTLIRFMVDIACGMEYLSSRNFIHRDLAARN
CMLAEDMTVCVADFGLSRKIYSGDYYRQGCASKLPVKWLALESLADNLYTVQSDVWAFGV
TMWEIMTRGQTPYAGIENAEIYNYLIGGNRLKQPPECMEDVYDLMYQCWSADPKQRPSFT
CLRMELENILGQLSVLSASQDPLYINIERAEEPTAGGSLELPGRDQPYSGAGDGSGMGAV
GGTPSDCRYILTPGGLAEQPGQAEHQPESPLNETQRLLLLQQGLLPHSSC

External Links

GenBank ID Protein

Not Available

UniProtKB/Swiss-Prot ID

Q06418

UniProtKB/Swiss-Prot Entry Name

TYRO3_HUMAN

PDB IDs