Cannabis Compound Database: Showing Protein Dual specificity testis-specific protein kinase 2 (CDBP01131)

Identification Biological properties Gene properties Protein properties External links References XML Show 2 compounds

Identification

HMDB Protein ID

CDBP01131

Secondary Accession Numbers

Not Available

Name

Dual specificity testis-specific protein kinase 2

Description

Not Available

Synonyms

Testicular protein kinase 2

Gene Name

TESK2

Protein Type

Enzyme

Biological Properties

General Function

Involved in protein kinase activity

Specific Function

Dual specificity protein kinase activity catalyzing autophosphorylation and phosphorylation of exogenous substrates on both serine/threonine and tyrosine residues. Phosphorylates cofilin at 'Ser-3'. May play an important role in spermatogenesis

GO Classification

Function
protein tyrosine kinase activity
binding
catalytic activity
transferase activity
transferase activity, transferring phosphorus-containing groups
kinase activity
nucleoside binding
purine nucleoside binding
adenyl nucleotide binding
adenyl ribonucleotide binding
atp binding
protein kinase activity
Process
protein amino acid phosphorylation
phosphorylation
phosphorus metabolic process
phosphate metabolic process
metabolic process
cellular metabolic process

Cellular Location

Nucleus

Pathways

Not Available

Gene Properties

Chromosome Location

Chromosome:1

Locus

1p32

SNPs

TESK2

Gene Sequence

>1716 bp
ATGGATCGGAGCAAACGGAATTCAATTGCAGGATTTCCTCCACGTGTGGAGCGTCTTGAA
GAGTTTGAAGGAGGTGGTGGAGGAGAAGGAAATGTGAGCCAGGTGGGAAGAGTTTGGCCA
TCTTCGTATCGAGCTCTTATAAGTGCCTTTTCCAGACTGACGCGTTTGGATGATTTCACC
TGTGAAAAAATAGGGTCTGGCTTCTTTTCTGAAGTGTTCAAGGTACGACACCGAGCTTCT
GGTCAGGTGATGGCTCTTAAGATGAACACATTGAGCAGTAACCGGGCAAACATGCTGAAA
GAAGTACAGCTCATGAATAGACTCTCCCATCCCAACATCCTTAGGTTCATGGGTGTATGT
GTTCATCAAGGACAATTGCATGCACTTACAGAGTATATCAACTCCGGGAACCTGGAACAG
TTGCTAGACAGTAACCTGCATTTGCCTTGGACTGTGAGGGTAAAACTGGCCTATGACATA
GCAGTGGGCCTCAGCTACCTTCACTTCAAAGGCATTTTTCATCGGGACCTCACATCTAAG
AACTGCCTGATAAAGAGGGATGAGAATGGTTACTCTGCAGTGGTAGCTGACTTTGGCCTG
GCTGAGAAGATCCCCGATGTCAGCATGGGGAGTGAGAAGCTGGCCGTGGTGGGTTCCCCA
TTCTGGATGGCACCTGAGGTTCTCCGAGATGAGCCCTATAATGAAAAGGCAGATGTGTTC
TCTTATGGTATCATCCTCTGCGAGATCATCGCCCGCATCCAGGCCGATCCGGACTATCTT
CCCCGCACAGAGAATTTCGGGCTGGACTATGATGCTTTCCAGCACATGGTGGGAGACTGT
CCCCCAGATTTTCTGCAACTTACTTTCAACTGCTGTAACATGGATCCCAAACTGCGCCCA
TCTTTTGTGGAGATTGGGAAGACCCTGGAGGAAATTCTGAGCCGCCTACAGGAAGAAGAG
CAGGAGAGGGATAGGAAGCTGCAGCCCACAGCCAGGGGACTCTTGGAGAAAGCACCTGGG
GTGAAGCGACTAAGCTCACTGGATGACAAGATCCCCCACAAGTCACCATGCCCAAGACGT
ACCATCTGGCTGTCTCGAAGCCAGTCAGATATCTTTTCCCGTAAGCCCCCACGTACAGTG
AGTGTCTTGGACCCATACTACCGGCCACGAGATGGTGCTGCCCGCACCCCCAAAGTCAAC
CCTTTTAGTGCTCGCCAGGACCTCATGGGGGGCAAGATCAAGTTTTTTGACCTGCCCAGC
AAGTCTGTCATCTCTCTGGTATTTGACCTGGATGCACCAGGGCCCGGAACTATGCCCCTG
GCTGACTGGCAGGAGCCCCTGGCCCCACCTATTCGCCGGTGGCGTTCCTTGCCTGGTTCG
CCTGAGTTCTTGCATCAAGAGGCTTGTCCATTTGTGGGCCGGGAAGAATCGCTATCTGAT
GGGCCCCCACCACGCCTAAGTAGTCTCAAGTACAGAGTTAAAGAGATCCCACCATTCCGG
GCATCTGCCCTACCAGCTGCTCAAGCCCATGAGGCTATGGACTGCTCCATTCTCCAGGAA
GAAAATGGTTTTGGGTCCAGGCCCCAGGGGACCAGTCCATGCCCTGCGGGTGCTTCTGAG
GAGATGGAGGTAGAAGAAAGGCCAGCAGGCTCAACTCCAGCCACCTTCTCCACCTCAGGC
ATAGGCCTGCAAACCCAGGGAAAGCAGGATGGGTGA

Protein Properties

Number of Residues

571

Molecular Weight

63638.8

Theoretical pI

7.06

Pfam Domain Function

Pkinase_Tyr (PF07714 )

Signals

["None"]

Transmembrane Regions

["None"]

Protein Sequence

>Dual specificity testis-specific protein kinase 2
MDRSKRNSIAGFPPRVERLEEFEGGGGGEGNVSQVGRVWPSSYRALISAFSRLTRLDDFT
CEKIGSGFFSEVFKVRHRASGQVMALKMNTLSSNRANMLKEVQLMNRLSHPNILRFMGVC
VHQGQLHALTEYINSGNLEQLLDSNLHLPWTVRVKLAYDIAVGLSYLHFKGIFHRDLTSK
NCLIKRDENGYSAVVADFGLAEKIPDVSMGSEKLAVVGSPFWMAPEVLRDEPYNEKADVF
SYGIILCEIIARIQADPDYLPRTENFGLDYDAFQHMVGDCPPDFLQLTFNCCNMDPKLRP
SFVEIGKTLEEILSRLQEEEQERDRKLQPTARGLLEKAPGVKRLSSLDDKIPHKSPCPRR
TIWLSRSQSDIFSRKPPRTVSVLDPYYRPRDGAARTPKVNPFSARQDLMGGKIKFFDLPS
KSVISLVFDLDAPGPGTMPLADWQEPLAPPIRRWRSLPGSPEFLHQEACPFVGREESLSD
GPPPRLSSLKYRVKEIPPFRASALPAAQAHEAMDCSILQEENGFGSRPQGTSPCPAGASE
EMEVEERPAGSTPATFSTSGIGLQTQGKQDG

External Links

GenBank ID Protein

15207801

UniProtKB/Swiss-Prot ID

Q96S53

UniProtKB/Swiss-Prot Entry Name

TESK2_HUMAN

PDB IDs

Not Available

GenBank Gene ID

AB057597

GeneCard ID