Cannabis Compound Database: Showing Protein Serine/threonine-protein kinase ICK (CDBP01122)

Identification Biological properties Gene properties Protein properties External links References XML Show 3 compounds

Identification

HMDB Protein ID

CDBP01122

Secondary Accession Numbers

Not Available

Name

Serine/threonine-protein kinase ICK

Description

Not Available

Synonyms

Intestinal cell kinase
LCK2
Laryngeal cancer kinase 2
MAK-related kinase
MRK
hICK

Gene Name

ICK

Protein Type

Enzyme

Biological Properties

General Function

Involved in protein kinase activity

Specific Function

May play a key role in the development of multiple organ systems and particularly in cardiac development

GO Classification

Function
atp binding
protein kinase activity
protein serine/threonine kinase activity
binding
catalytic activity
transferase activity
transferase activity, transferring phosphorus-containing groups
kinase activity
nucleoside binding
purine nucleoside binding
adenyl nucleotide binding
adenyl ribonucleotide binding
Process
phosphorus metabolic process
phosphate metabolic process
metabolic process
cellular metabolic process
protein amino acid phosphorylation
phosphorylation

Cellular Location

Nucleus
Cytoplasm
cytosol

Pathways

Not Available

Gene Properties

Chromosome Location

Chromosome:6

Locus

6p12.1

SNPs

ICK

Gene Sequence

>1899 bp
ATGAATAGATACACAACAATCAGGCAGCTCGGGGATGGAACCTACGGTTCCGTCCTGCTG
GGAAGAAGCATTGAGTCTGGGGAGCTGATCGCTATTAAAAAAATGAAAAGAAAATTTTAT
TCCTGGGAGGAATGCATGAACCTTCGGGAGGTTAAGTCTTTAAAGAAGCTCAACCATGCC
AATGTAGTCAAATTAAAAGAAGTTATCAGGGAAAATGATCATCTTTATTTTATCTTCGAG
TACATGAAGGAAAATCTTTACCAGCTCATTAAAGAGAGAAATAAGTTGTTTCCTGAGTCT
GCTATAAGGAATATCATGTATCAGATATTACAAGGACTCGCATTTATTCACAAACACGGC
TTCTTTCATCGAGACTTAAAGCCTGAGAACCTCCTCTGCATGGGACCAGAACTTGTGAAA
ATTGCAGACTTTGGTTTGGCCCGAGAAATACGATCAAAACCTCCATATACAGATTATGTA
TCTACCAGATGGTACAGGGCTCCAGAAGTACTCCTGAGGTCTACCAACTACAGCTCCCCC
ATTGACGTCTGGGCGGTGGGCTGCATCATGGCAGAAGTTTACACCCTCAGGCCACTCTTC
CCTGGAGCCAGTGAAATTGACACAATATTCAAAATTTGCCAAGTGCTGGGGACACCAAAA
AAGACTGACTGGCCTGAAGGCTATCAACTTTCAAGTGCAATGAACTTCCGTTGGCCACAG
TGTGTACCCAATAACTTAAAGACCTTGATTCCCAATGCTAGCAGTGAAGCAGTCCAGCTC
CTGAGAGACATGCTTCAGTGGGATCCCAAGAAACGACCAACAGCTAGTCAGGCACTTCGA
TATCCTTACTTCCAAGTTGGACACCCACTAGGCAGCACCACACAAAACCTTCAGGATTCA
GAAAAACCACAGAAAGGCATCCTGGAAAAGGCAGGCCCACCTCCTTATATTAAGCCAGTC
CCACCTGCCCAGCCACCAGCCAAGCCACACACACGAATTTCTTCACGACAGCATCAAGCC
AGCCAGCCCCCTCTGCATCTCACGTACCCCTACAAAGCAGAGGTCTCCAGGACAGATCAC
CCAAGCCATCTCCAGGAGGACAAGCCAAGCCCGTTGCTTTTCCCATCCCTCCACAACAAG
CATCCACAGTCGAAAATCACAGCTGGCCTGGAGCACAAAAATGGTGAGATAAAGCCAAAG
AGTAGGAGAAGGTGGGGTCTTATTTCCAGGTCAACAAAGGATTCAGATGATTGGGCTGAC
TTGGATGACTTGGATTTCAGTCCATCCCTCAGCAGGATTGACCTGAAAAACAAGAAAAGA
CAGAGTGATGACACTCTCTGCAGGTTTGAGAGTGTTTTGGACCTGAAGCCCTCTGAGCCT
GTGGGCACAGGAAACAGTGCCCCCACCCAGACGTCATATCAGCGGCGAGACACGCCCACC
CTGAGATCTGCAGCCAAGCAGCACTATTTGAAGCACTCTCGATACTTGCCTGGGATCAGT
ATAAGAAATGGCATACTCTCGAATCCAGGCAAGGAATTTATTCCACCTAATCCATGGTCT
AGTTCTGGCTTGTCTGGAAAATCTTCAGGGACAATGTCAGTAATCAGCAAAGTAAATTCA
GTTGGTTCCAGCTCTACAAGTTCTAGTGGACTGACTGGAAACTATGTCCCTTCCTTTCTG
AAAAAAGAAATCGGTTCTGCTATGCAGAGGGTACACCTAGCACCTATTCCAGACCCTTCC
CCTGGTTATTCCTCCCTGAAGGCCATGAGACCTCATCCTGGGCGACCATTCTTCCACACC
CAGCCTAGAAGCACTCCTGGGTTGATACCACGGCCTCCAGCCGCCCAGCCAGTGCATGGC
CGGACAGACTGGGCTTCCAAGTACGCATCTCGGCGATGA

Protein Properties

Number of Residues

632

Molecular Weight

71426.1

Theoretical pI

10.32

Pfam Domain Function

Pkinase (PF00069 )

Signals

["None"]

Transmembrane Regions

["None"]

Protein Sequence

>Serine/threonine-protein kinase ICK
MNRYTTIRQLGDGTYGSVLLGRSIESGELIAIKKMKRKFYSWEECMNLREVKSLKKLNHA
NVVKLKEVIRENDHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFIHKHG
FFHRDLKPENLLCMGPELVKIADFGLAREIRSKPPYTDYVSTRWYRAPEVLLRSTNYSSP
IDVWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLGTPKKTDWPEGYQLSSAMNFRWPQ
CVPNNLKTLIPNASSEAVQLLRDMLQWDPKKRPTASQALRYPYFQVGHPLGSTTQNLQDS
EKPQKGILEKAGPPPYIKPVPPAQPPAKPHTRISSRQHQASQPPLHLTYPYKAEVSRTDH
PSHLQEDKPSPLLFPSLHNKHPQSKITAGLEHKNGEIKPKSRRRWGLISRSTKDSDDWAD
LDDLDFSPSLSRIDLKNKKRQSDDTLCRFESVLDLKPSEPVGTGNSAPTQTSYQRRDTPT
LRSAAKQHYLKHSRYLPGISIRNGILSNPGKEFIPPNPWSSSGLSGKSSGTMSVISKVNS
VGSSSTSSSGLTGNYVPSFLKKEIGSAMQRVHLAPIPDPSPGYSSLKAMRPHPGRPFFHT
QPRSTPGLIPRPPAAQPVHGRTDWASKYASRR

External Links

GenBank ID Protein

7662388

UniProtKB/Swiss-Prot ID

Q9UPZ9

UniProtKB/Swiss-Prot Entry Name

ICK_HUMAN

PDB IDs

Not Available

GenBank Gene ID

NM_014920.3

GeneCard ID