Cannabis Compound Database: Showing Protein Ephrin type-A receptor 5 (CDBP01097)

Identification Biological properties Gene properties Protein properties External links References XML Show 2 compounds

Identification

HMDB Protein ID

CDBP01097

Secondary Accession Numbers

Not Available

Name

Ephrin type-A receptor 5

Description

Not Available

Synonyms

EHK-1
EK7
EPH homology kinase 1
EPH-like kinase 7
hEK7

Gene Name

EPHA5

Protein Type

Enzyme

Biological Properties

General Function

Involved in ephrin receptor activity

Specific Function

Receptor for members of the ephrin-A family. Binds to ephrin-A1, -A2, -A3, -A4 and -A5

GO Classification

Component
integral to plasma membrane
membrane
cell part
membrane part
intrinsic to membrane
integral to membrane
Function
transferase activity, transferring phosphorus-containing groups
kinase activity
nucleoside binding
purine nucleoside binding
adenyl nucleotide binding
adenyl ribonucleotide binding
atp binding
ephrin receptor activity
protein binding
protein kinase activity
protein tyrosine kinase activity
transmembrane receptor protein tyrosine kinase activity
binding
catalytic activity
transferase activity
Process
protein amino acid phosphorylation
signaling
signaling pathway
cell surface receptor linked signaling pathway
phosphorylation
phosphorus metabolic process
phosphate metabolic process
enzyme linked receptor protein signaling pathway
transmembrane receptor protein tyrosine kinase signaling pathway
metabolic process
cellular metabolic process

Cellular Location

Membrane
Single-pass type I membrane protein

Pathways

Not Available

Gene Properties

Chromosome Location

Chromosome:4

Locus

4q13.1

SNPs

EPHA5

Gene Sequence

>3114 bp
ATGCGGGGCTCGGGGCCCCGGGGTGCGGGACGCCGGCGGCCCCCAAGCGGCGGCGGCGAC
ACCCCCATCACCCCAGCGTCCCTGGCCGGCTGCTACTCTGCACCTCGACGGGCTCCCCTC
TGGACGTGCCTTCTCCTGTGCGCCGCACTCCGGACCCTCCTGGCCAGCCCCAGCAACGAA
GTGAATTTATTGGATTCACGCACTGTCATGGGGGACCTGGGATGGATTGCTTTTCCAAAA
AATGGGTGGGAAGAGATTGGTGAAGTGGATGAAAATTATGCCCCTATCCACACATACCAA
GTATGCAAAGTGATGGAACAGAATCAGAATAACTGGCTTTTGACCAGTTGGATCTCCAAT
GAAGGTGCTTCCAGAATCTTCATAGAACTCAAATTTACCCTGCGGGACTGCAACAGCCTT
CCTGGAGGACTGGGGACCTGTAAGGAAACCTTTAATATGTATTACTTTGAGTCAGATGAT
CAGAATGGGAGAAACATCAAGGAAAACCAATACATCAAAATTGATACCATTGCTGCCGAT
GAAAGCTTTACAGAACTTGATCTTGGTGACCGTGTTATGAAACTGAATACAGAGGTCAGA
GATGTAGGACCTCTAAGCAAAAAGGGATTTTATCTTGCTTTTCAAGATGTTGGTGCTTGC
ATTGCTCTGGTTTCTGTGCGTGTATACTATAAAAAATGCCCTTCTGTGGTACGACACTTG
GCTGTCTTCCCTGACACCATCACTGGAGCTGATTCTTCCCAATTGCTCGAAGTGTCAGGC
TCCTGTGTCAACCATTCTGTGACCGATGAACCTCCCAAAATGCACTGCAGCGCCGAAGGG
GAGTGGCTGGTGCCCATCGGGAAATGCATGTGCAAGGCAGGATATGAAGAGAAAAATGGC
ACCTGTCAAGTGTGCAGACCTGGGTTCTTCAAAGCCTCACCTCACATCCAGAGCTGCGGC
AAATGTCCACCTCACAGTTATACCCATGAGGAAGCTTCAACCTCTTGTGTCTGTGAAAAG
GATTATTTCAGGAGAGAGTCTGATCCACCCACAATGGCATGCACAAGACCCCCCTCTGCT
CCTCGGAATGCCATCTCAAATGTTAATGAAACTAGTGTCTTTCTGGAATGGATTCCGCCT
GCTGACACTGGTGGAAGGAAAGACGTGTCATATTATATTGCATGCAAGAAGTGCAACTCC
CATGCAGGTGTGTGTGAGGAGTGTGGCGGTCATGTCAGGTACCTTCCCCGGCAAAGCGGC
CTGAAAAACACCTCTGTCATGATGGTGGATCTACTCGCTCACACAAACTATACCTTTGAG
ATTGAGGCAGTGAATGGAGTGTCCGACTTGAGCCCAGGAGCCCGGCAGTATGTGTCTGTA
AATGTAACCACAAATCAAGCAGCTCCATCTCCAGTCACCAATGTGAAAAAAGGGAAAATT
GCAAAAAACAGCATCTCTTTGTCTTGGCAAGAACCAGATCGTCCCAATGGAATCATCCTA
GAGTATGAAATCAAGTATTTTGAAAAGGACCAAGAGACCAGCTACACGATTATCAAATCT
AAAGAGACAACTATTACTGCAGAGGGCTTGAAACCAGCTTCAGTTTATGTCTTCCAAATT
CGAGCACGTACAGCAGCAGGCTATGGTGTCTTCAGTCGAAGATTTGAGTTTGAAACCACC
CCAGTGTTTGCAGCATCCAGCGATCAAAGCCAGATTCCTGTAATTGCTGTGTCTGTGACA
GTGGGAGTCATTTTGTTGGCAGTGGTTATCGGCGTCCTCCTCAGTGGAAGTTGCTGCGAA
TGTGGCTGTGGGAGGGCTTCTTCCCTGTGCGCTGTTGCCCATCCAAGCCTAATATGGCGG
TGTGGCTACAGCAAAGCAAAACAAGATCCAGAAGAGGAAAAGATGCATTTTCATAATGGG
CACATTAAACTGCCAGGAGTAAGAACTTACATTGATCCACATACCTATGAGGATCCCAAT
CAAGCTGTCCACGAATTTGCTAAGGAGATAGAAGCATCATGTATCACCATTGAGAGAGTT
ATTGGAGCAGGTGAATTTGGTGAAGTTTGTAGTGGACGTTTGAAACTACCAGGAAAAAGA
GAATTACCTGTGGCTATCAAAACCCTTAAAGTAGGCTATACTGAAAAGCAACGCAGAGAT
TTCCTAGGTGAAGCAAGTATCATGGGACAGTTTGATCATCCTAACATCATCCATTTAGAA
GGTGTGGTGACCAAAAGTAAACCAGTGATGATCGTGACAGAGTATATGGAGAATGGCTCT
TTAGATACATTTTTGAAGAAAAACGATGGGCAGTTCACTGTGATTCAGCTTGTTGGCATG
CTGAGAGGTATCTCTGCAGGAATGAAGTACCTTTCTGACATGGGCTATGTGCATAGAGAT
CTTGCTGCCAGAAACATCTTAATCAACAGTAACCTTGTGTGCAAAGTGTCTGACTTTGGA
CTTTCCCGGGTACTGGAAGATGATCCCGAGGCAGCCTACACCACAAGGGGAGGAAAAATT
CCAATCAGATGGACTGCCCCAGAAGCAATAGCTTTCCGAAAGTTTACTTCTGCCAGTGAT
GTCTGGAGTTATGGAATAGTAATGTGGGAAGTTGTGTCTTATGGAGAGAGACCCTACTGG
GAGATGACCAATCAAGATGTGATTAAAGCGGTAGAGGAAGGCTATCGTCTGCCAAGCCCC
ATGGATTGTCCTGCTGCTCTCTATCAGTTAATGCTGGATTGCTGGCAGAAAGAGCGAAAT
AGCAGGCCCAAGTTTGATGAAATAGTCAACATGTTGGACAAGCTGATACGTAACCCAAGT
AGTCTGAAGACGCTGGTTAATGCATCCTGCAGAGTATCTAATTTATTGGCAGAACATAGC
CCACTAGGATCTGGGGCCTACAGATCAGTAGGTGAATGGCTAGAGGCAATCAAGATGGGC
CGGTATACAGAGATTTTCATGGAAAATGGATACAGTTCAATGGACGCTGTGGCTCAGGTG
ACCTTGGAGGATTTGAGACGGCTTGGAGTGACTCTTGTCGGTCACCAGAAGAAGATCATG
AACAGCCTTCAAGAAATGAAGGTGCAGCTGGTAAACGGAATGGTGCCATTGTAA

Protein Properties

Number of Residues

1037

Molecular Weight

114802.3

Theoretical pI

6.92

Pfam Domain Function

SAM_1 (PF00536 )
Pkinase_Tyr (PF07714 )
Ephrin_lbd (PF01404 )
fn3 (PF00041 )

Signals

["1-24"]

Transmembrane Regions

["574-594"]

Protein Sequence

>Ephrin type-A receptor 5
MRGSGPRGAGRRRPPSGGGDTPITPASLAGCYSAPRRAPLWTCLLLCAALRTLLASPSNE
VNLLDSRTVMGDLGWIAFPKNGWEEIGEVDENYAPIHTYQVCKVMEQNQNNWLLTSWISN
EGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESDDQNGRNIKENQYIKIDTIAAD
ESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDVGACIALVSVRVYYKKCPSVVRHL
AVFPDTITGADSSQLLEVSGSCVNHSVTDEPPKMHCSAEGEWLVPIGKCMCKAGYEEKNG
TCQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCVCEKDYFRRESDPPTMACTRPPSA
PRNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKKCNSHAGVCEECGGHVRYLPRQSG
LKNTSVMMVDLLAHTNYTFEIEAVNGVSDLSPGARQYVSVNVTTNQAAPSPVTNVKKGKI
AKNSISLSWQEPDRPNGIILEYEIKYFEKDQETSYTIIKSKETTITAEGLKPASVYVFQI
RARTAAGYGVFSRRFEFETTPVFAASSDQSQIPVIAVSVTVGVILLAVVIGVLLSGSCCE
CGCGRASSLCAVAHPSLIWRCGYSKAKQDPEEEKMHFHNGHIKLPGVRTYIDPHTYEDPN
QAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQRRD
FLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVGM
LRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKI
PIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYRLPSP
MDCPAALYQLMLDCWQKERNSRPKFDEIVNMLDKLIRNPSSLKTLVNASCRVSNLLAEHS
PLGSGAYRSVGEWLEAIKMGRYTEIFMENGYSSMDAVAQVTLEDLRRLGVTLVGHQKKIM
NSLQEMKVQLVNGMVPL

External Links

GenBank ID Protein

221625401

UniProtKB/Swiss-Prot ID

P54756

UniProtKB/Swiss-Prot Entry Name

EPHA5_HUMAN

PDB IDs

Not Available

GenBank Gene ID

NM_004439.5

GeneCard ID