| Identification |
| HMDB Protein ID
| CDBP01079 |
| Secondary Accession Numbers
| Not Available |
| Name
| Receptor-interacting serine/threonine-protein kinase 3 |
| Description
| Not Available |
| Synonyms
|
- RIP-3
- RIP-like protein kinase 3
- Receptor-interacting protein 3
|
| Gene Name
| RIPK3 |
| Protein Type
| Enzyme |
| Biological Properties |
| General Function
| Involved in protein kinase activity |
| Specific Function
| Promotes apoptosis |
| GO Classification
|
| Function |
| protein kinase activity |
| protein serine/threonine kinase activity |
| binding |
| catalytic activity |
| transferase activity |
| transferase activity, transferring phosphorus-containing groups |
| kinase activity |
| nucleoside binding |
| purine nucleoside binding |
| adenyl nucleotide binding |
| adenyl ribonucleotide binding |
| atp binding |
| Process |
| phosphorus metabolic process |
| phosphate metabolic process |
| metabolic process |
| cellular metabolic process |
| protein amino acid phosphorylation |
| phosphorylation |
|
| Cellular Location
|
- Cytoplasm (Probable)
|
| Pathways
|
Not Available
|
| Gene Properties |
| Chromosome Location
| Chromosome:1 |
| Locus
| 14q11.2 |
| SNPs
| RIPK3 |
| Gene Sequence
|
>1557 bp
ATGTCGTGCGTCAAGTTATGGCCCAGCGGTGCCCCCGCCCCCTTGGTGTCCATCGAGGAA
CTGGAGAACCAGGAGCTCGTCGGCAAAGACGGGTTCGGCACAGTGTTCCGGGCGCAACAT
AGGAAGTGGGGCTACGATGTGGCGGTCAAGATCGTAAACTCGAAGGCGATATCCAGGGAG
GTCAAGGCCATGGCAAGTCTGGATAACGAATTCGTGTTGCGCCTAGAAGGGGTTATCGAG
AAGGTGAACTGGGACCAAGATCCCAAGCCGGCTCTGGTGACTAAATTCATGGAGAACGGC
TCCCTGTCGGGGCTGCTGCAGTCCCAGTGCCCTCGGCCCTGGCCGCTCCTTTGCCGCCTG
CTGAAAGAAGTGGTGCTTGGGATGTTTTACCTGCACGACCAGAACCCGGTGCTCCTGCAC
CGGGACCTCAAGCCATCCAACGTCCTGCCGGACCCAGAGCTGCACGTCAAGCTGGCAGAT
TTTGGCCTGTCCACATTTCAGGGAGGCTCACAGTCAGGGACAGGGTCCGGGGAGCCAGGG
GGCACCCTGGGCTACTTGGCCCCAGAACTGTTTGTTAACGTAAACCGGAAGGCCTCCACA
GCCAGTGACGTCTACAGCTTCGGGATCCTAATGTGGGCAGTGCTTGCTGGAAGAGAAGTT
GAGTTGCCAACCGAACCATCACTCGTGTACGAAGCAGTGTGCAACAGGCAGAACCGGCCT
TCATTGGCTGAGCTGCCCCAAGCCGGGCCTGAGACTCCCGGCTTAGAAGGACTGAAGGAG
CTAATGCAGCTCTGCTGGAGCAGTGAGCCCAAGGACAGACCCTCCTTCCAGGAATGCCTA
CCAAAAACTGATGAAGTCTTCCAGATGGTGGAGAACAATATGAATGCTGCTGTCTCCACG
GTAAAGGATTTCCTGTCTCAGCTCAAGAGCAGCAATAGGAGATTTTCTATCCCAGAGTCA
GGCCAAGGAGGGACAGAAATGGATGGCTTTAGGAGAACCATAGAAAACCAGCACTCTCGT
AATGATGTCATGGTTTCTGAGTGGCTAAACAAACTGAATCTAGAGGAGCCTCCCAGCTCT
GTTCCTAAAAAATGCCCGAGCCTTACCAAGAGGAGCAGGGCACAAGAGGAGCAGGTTCCA
CAAGCCTGGACAGCAGGCACATCTTCAGATTCGATGGCCCAACCTCCCCAGACTCCAGAG
ACCTCAACTTTCAGAAACCAGATGCCCAGCCCTACCTCAACTGGAACACCAAGTCCTGGA
CCCCGAGGGAATCAGGGGGCTGAGAGACAAGGCATGAACTGGTCCTGCAGGACCCCGGAG
CCAAATCCAGTAACAGGGCGACCGCTCGTTAACATATACAACTGCTCTGGGGTGCAAGTT
GGAGACAACAACTACTTGACTATGCAACAGACAACTGCCTTGCCCACATGGGGCTTGGCA
CCTTCGGGCAAGGGGAGGGGCTTGCAGCACCCCCCACCAGTAGGTTCGCAAGAAGGCCCT
AAAGATCCTGAAGCCTGGAGCAGGCCACAGGGTTGGTATAATCATAGCGGGAAATAA
|
| Protein Properties |
| Number of Residues
| 518 |
| Molecular Weight
| 56886.9 |
| Theoretical pI
| 6.41 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Receptor-interacting serine/threonine-protein kinase 3
MSCVKLWPSGAPAPLVSIEELENQELVGKGGFGTVFRAQHRKWGYDVAVKIVNSKAISRE
VKAMASLDNEFVLRLEGVIEKVNWDQDPKPALVTKFMENGSLSGLLQSQCPRPWPLLCRL
LKEVVLGMFYLHDQNPVLLHRDLKPSNVLLDPELHVKLADFGLSTFQGGSQSGTGSGEPG
GTLGYLAPELFVNVNRKASTASDVYSFGILMWAVLAGREVELPTEPSLVYEAVCNRQNRP
SLAELPQAGPETPGLEGLKELMQLCWSSEPKDRPSFQECLPKTDEVFQMVENNMNAAVST
VKDFLSQLRSSNRRFSIPESGQGGTEMDGFRRTIENQHSRNDVMVSEWLNKLNLEEPPSS
VPKKCPSLTKRSRAQEEQVPQAWTAGTSSDSMAQPPQTPETSTFRNQMPSPTSTGTPSPG
PRGNQGAERQGMNWSCRTPEPNPVTGRPLVNIYNCSGVQVGDNNYLTMQQTTALPTWGLA
PSGKGRGLQHPPPVGSQEGPKDPEAWSRPQGWYNHSGK
|
| External Links |
| GenBank ID Protein
| 5059425 |
| UniProtKB/Swiss-Prot ID
| Q9Y572 |
| UniProtKB/Swiss-Prot Entry Name
| RIPK3_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AF156884 |
| GeneCard ID
| RIPK3 |
| GenAtlas ID
| RIPK3 |
| HGNC ID
| HGNC:10021 |
| References |
| General References
| Not Available |