Cannabis Compound Database: Showing Protein cGMP-dependent protein kinase 1 (CDBP01054)

Identification Biological properties Gene properties Protein properties External links References XML Show 2 compounds

Identification

HMDB Protein ID

CDBP01054

Secondary Accession Numbers

Not Available

Name

cGMP-dependent protein kinase 1

Description

Not Available

Synonyms

cGK 1
cGK1
cGKI
cGMP-dependent protein kinase I

Gene Name

PRKG1

Protein Type

Enzyme

Biological Properties

General Function

Involved in protein serine/threonine kinase activity

Specific Function

Phosphorylates PPP1R12A

GO Classification

Function
protein serine/threonine kinase activity
cyclic nucleotide-dependent protein kinase activity
cgmp-dependent protein kinase activity
binding
catalytic activity
transferase activity
transferase activity, transferring phosphorus-containing groups
kinase activity
nucleoside binding
purine nucleoside binding
adenyl nucleotide binding
adenyl ribonucleotide binding
atp binding
protein kinase activity
Process
phosphorus metabolic process
phosphate metabolic process
metabolic process
cellular metabolic process
protein amino acid phosphorylation
phosphorylation

Cellular Location

Not Available

Pathways

Not Available

Gene Properties

Chromosome Location

Chromosome:1

Locus

10q11.2

SNPs

PRKG1

Gene Sequence

>2016 bp
ATGAGCGAGCTAGAGGAAGACTTTGCCAAGATTCTCATGCTCAAGGAGGAGAGGATCAAA
GAGCTGGAGAAGCGGCTGTCAGAGAAGGAGGAAGAAATTCAGGAGCTGAAGAGGAAACTC
CACAAATGCCAGTCGGTGCTCCCAGTGCCCTCGACCCACATCGGCCCCCGGACCACCCGG
GCGCAGGGCATCTCGGCCGAGCCGCAGACGTACAGGTCCTTCCACGACCTCCGACAGGCA
TTCCGGAAGTTCACCAAGTCCGAAAGGTCCAAGGATCTTATAAAGGAAGCTATCCTTGAC
AATGACTTTATGAAGAACTTGGAGCTGTCGCAGATCCAGGAGATTGTGGATTGTATGTAC
CCGGTGGAGTATGGCAAGGACAGTTGCATCATCAAAGAAGGAGACGTGGGGTCACTGGTG
TATGTCATGGAAGATGGTAAGGTTGAAGTTACAAAAGAAGGTGTGAAGTTGTGTACCATG
GGTCCAGGAAAAGTGTTTGGGGAATTGGCTATTCTTTACAACTGTACCCGGACAGCGACC
GTCAAGACTCTTGTAAATGTAAAACTCTGGGCCATTGATCGACAATGTTTTCAAACAATA
ATGATGAGGACAGGACTCATCAAGCATACCGAGTATATGGAATTTTTAAAAAGCGTTCCA
ACATTCCAGAGCCTTCCTGAAGAGATCCTCAGCAAGCTTGCTGATGTCCTTGAAGAGACC
CACTATGAAAATGGAGAATATATTATCAGGCAAGGTGCAAGAGGGGACACCTTCTTTATC
ATCAGCAAAGGAACGGTAAATGTCACTCGTGAAGACTCACCGAGTGAAGACCCAGTCTTT
CTTAGAACTTTAGGAAAAGGAGACTGGTTTGGAGAGAAAGCCTTGCAGGGGGAAGATGTG
AGAACAGCAAACGTAATTGCTGCAGAAGCTGTAACCTGCCTTGTGATTGACAGAGACTCT
TTTAAACATTTGATTGGAGGGCTGGATGATGTTTCTAATAAAGCATATGAAGATGCAGAA
GCTAAAGCAAAATATGAAGCTGAAGCGGCTTTCTTCGCCAACCTGAAGCTGTCTGATTTC
AACATCATTGATACCCTTGGAGTTGGAGGTTTCGGACGAGTAGAACTGGTCCAGTTGAAA
AGTGAAGAATCCAAAACGTTTGCAATGAAGATTCTCAAGAAACGTCACATTGTGGACACA
AGACAGCAGGAGCACATCCGCTCAGAGAAGCAGATCATGCAGGGGGCTCATTCCGATTTC
ATAGTGAGACTGTACAGAACATTTAAGGACAGCAAATATTTGTATATGTTGATGGAAGCT
TGTCTAGGTGGAGAGCTCTGGACCATTCTCAGGGATAGAGGTTCGTTTGAAGATTCTACA
ACCAGATTTTACACAGCATGTGTGGTAGAAGCTTTTGCCTATCTGCATTCCAAAGGAATC
ATTTACAGGGACCTCAAGCCAGAAAATCTCATCCTAGATCACCGAGGTTATGCCAAACTG
GTTGATTTTGGCTTTGCAAAGAAAATAGGATTTGGAAAGAAAACATGGACTTTTTGTGGG
ACTCCAGAGTATGTAGCCCCAGAGATCATCCTGAACAAAGGCCATGACATTTCAGCCGAC
TACTGGTCACTGGGAATCCTAATGTATGAACTCCTGACTGGCAGCCCACCTTTCTCAGGC
CCAGATCCTATGAAAACCTATAACATCATATTGAGGGGGATTGACATGATAGAATTTCCA
AAGAAGATTGCCAAAAATGCTGCTAATTTAATTAAAAAACTATGCAGGGACAATCCATCA
GAAAGATTAGGGAATTTGAAAAATGGAGTAAAAGACATTCAAAAGCACAAATGGTTTGAG
GGCTTTAACTGGGAAGGCTTAAGAAAAGGTACCTTGACACCTCCTATAATACCAAGTGTT
GCATCACCCACAGACACAAGTAATTTTGACAGTTTCCCTGAGGACAACGATGAACCACCA
CCTGATGACAACTCAGGATGGGATATAGACTTCTAA

Protein Properties

Number of Residues

671

Molecular Weight

76363.8

Theoretical pI

5.87

Pfam Domain Function

cNMP_binding (PF00027 )
Pkinase (PF00069 )

Signals

["None"]

Transmembrane Regions

["None"]

Protein Sequence

>cGMP-dependent protein kinase 1
MSELEEDFAKILMLKEERIKELEKRLSEKEEEIQELKRKLHKCQSVLPVPSTHIGPRTTR
AQGISAEPQTYRSFHDLRQAFRKFTKSERSKDLIKEAILDNDFMKNLELSQIQEIVDCMY
PVEYGKDSCIIKEGDVGSLVYVMEDGKVEVTKEGVKLCTMGPGKVFGELAILYNCTRTAT
VKTLVNVKLWAIDRQCFQTIMMRTGLIKHTEYMEFLKSVPTFQSLPEEILSKLADVLEET
HYENGEYIIRQGARGDTFFIISKGTVNVTREDSPSEDPVFLRTLGKGDWFGEKALQGEDV
RTANVIAAEAVTCLVIDRDSFKHLIGGLDDVSNKAYEDAEAKAKYEAEAAFFANLKLSDF
NIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQIMQGAHSDF
IVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLHSKGI
IYRDLKPENLILDHRGYAKLVDFGFAKKIGFGKKTWTFCGTPEYVAPEIILNKGHDISAD
YWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKIAKNAANLIKKLCRDNPS
ERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTPPIIPSVASPTDTSNFDSFPEDNDEPP
PDDNSGWDIDF

External Links

GenBank ID Protein

148612818

UniProtKB/Swiss-Prot ID

Q13976

UniProtKB/Swiss-Prot Entry Name

KGP1_HUMAN

PDB IDs

Not Available

GenBank Gene ID

NM_001098512.1

GeneCard ID