| Identification |
|---|
| HMDB Protein ID
| CDBP01036 |
| Secondary Accession Numbers
| Not Available |
| Name
| Beta-1,3-galactosyltransferase 4 |
| Description
| Not Available |
| Synonyms
|
- Beta-1,3-GalTase 4
- Beta3Gal-T4
- Beta3GalT4
- Gal-T2
- GalT4
- Ganglioside galactosyltransferase
- UDP-galactose:beta-N-acetyl-galactosamine-beta-1,3-galactosyltransferase
- b3Gal-T4
|
| Gene Name
| B3GALT4 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in galactosyltransferase activity |
| Specific Function
| Involved in GM1/GD1B/GA1 ganglioside biosynthesis.
|
| GO Classification
|
| Biological Process |
| protein glycosylation |
| Cellular Component |
| Golgi membrane |
| integral to membrane |
| Component |
| membrane |
| cell part |
| Function |
| galactosyltransferase activity |
| catalytic activity |
| transferase activity |
| transferase activity, transferring hexosyl groups |
| transferase activity, transferring glycosyl groups |
| Molecular Function |
| ganglioside galactosyltransferase activity |
| UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity |
| Process |
| metabolic process |
| macromolecule metabolic process |
| macromolecule modification |
| protein modification process |
| protein amino acid glycosylation |
|
| Cellular Location
|
- Golgi apparatus membrane
- Single-pass type II membrane protein
|
| Pathways
|
| Name | SMPDB/Pathwhiz | KEGG | | protein glycosylation | Not Available | Not Available | | Other types of O-glycan biosynthesis | Not Available |  | | Glycosphingolipid biosynthesis - ganglio series | Not Available |  |
|
| Gene Properties |
|---|
| Chromosome Location
| 6 |
| Locus
| 6p21.3 |
| SNPs
| B3GALT4 |
| Gene Sequence
|
>1137 bp
ATGCAGCTCAGGCTCTTCCGGCGCCTCCTTCTCGCCGCTTTGCTGCTGGTGATCGTCTGG
ACCCTCTTCGGGCCTTCGGGGTTGGGGGAGGAGCTGCTGAGCCTCTCACTAGCCTCCCTG
CTCCCAGCCCCCGCCTCACCGGGGCCGCCCCTGGCCCTGCCCCGCCTCTTGATCCCCAAC
CAGGAAGCTTGCAGTGGTCCCGGGGCCCCTCCCTTCCTGCTCATCCTGGTGTGCACGGCT
CCGGAGAACCTGAACCAGAGAAACGCCATTCGGGCTTCGTGGGGCGGGCTGCGCGAGGCC
CGGGGGCTCAGGGTACAGACGCTATTCTTGCTGGGAGAGCCGAACGCACAGCACCCCGTG
TGGGGTTCCCAGGGGAGTGACCTGGCCTCGGAGTCAGCAGCCCAGGGGGATATCTTGCAG
GCCGCCTTCCAGGACTCCTACCGCAACCTCACCCTAAAGACCCTCAGCGGGCTGAACTGG
GCTGAGAAACACTGCCCCATGGCCCGATACGTCCTCAAGACGGACGATGATGTGTATGTC
AACGTCCCTGAACTGGTATCAGAGCTGGTCTTGCGAGGGGGCCGTTGGGGGCAATGGGAG
AGAAGCACGGAACCCCAGAGAGAGGCTGAGCAGGAAGGAGGCCAGGTTTTGCACAGCGAG
GAAGTGCCTCTTCTGTACTTGGGCCGGGTGCACTGGCGCGTGAACCCCTCTCGGACACCG
GGGGGCAGGCACCGCGTATCAGAGGAGCAGTGGCCTCACACCTGGGGCCCCTTTCCACCC
TATGCCTCAGGCACGGGGTATGTGCTGTCAGCGTCTGCTGTGCAGCTCATTCTCAAGGTG
GCCAGCCGGGCACCCCTTCTCCCATTAGAGGATGTCTTTGTGGGGGTAAGTGCCCGACGA
GGAGGCCTCGCCCCAACACAGTGTGTCAAGCTGGCTGGTGCCACCCACTACCCGCTAGAC
CGGTGCTGCTATGGGAAATTCCTGCTGACGTCCCACAGGCTGGACCCCTGGAAGATGCAG
GAAGCCTGGAAGCTGGTGGGTGGCTCTGACGGGGAAAGGACTGCGCCCTTTTGCTCCTGG
TTCCAGGGAGTCCTGGGCATCCTGCGGTGTCGAGCAATAGCCTGGCTTCAGAGCTGA
|
| Protein Properties |
|---|
| Number of Residues
| 378 |
| Molecular Weight
| 41536.435 |
| Theoretical pI
| 8.308 |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Beta-1,3-galactosyltransferase 4
MQLRLFRRLLLAALLLVIVWTLFGPSGLGEELLSLSLASLLPAPASPGPPLALPRLLIPN
QEACSGPGAPPFLLILVCTAPENLNQRNAIRASWGGLREARGLRVQTLFLLGEPNAQHPV
WGSQGSDLASESAAQGDILQAAFQDSYRNLTLKTLSGLNWAEKHCPMARYVLKTDDDVYV
NVPELVSELVLRGGRWGQWERSTEPQREAEQEGGQVLHSEEVPLLYLGRVHWRVNPSRTP
GGRHRVSEEQWPHTWGPFPPYASGTGYVLSASAVQLILKVASRAPLLPLEDVFVGVSARR
GGLAPTQCVKLAGATHYPLDRCCYGKFLLTSHRLDPWKMQEAWKLVGGSDGERTAPFCSW
FQGVLGILRCRAIAWLQS
|
| External Links |
|---|
| GenBank ID Protein
| 6683014 |
| UniProtKB/Swiss-Prot ID
| O96024 |
| UniProtKB/Swiss-Prot Entry Name
| B3GT4_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AB026730 |
| GeneCard ID
| B3GALT4 |
| GenAtlas ID
| B3GALT4 |
| HGNC ID
| HGNC:919 |
| References |
|---|
| General References
| Not Available |