Showing Protein UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase (CDBP01030)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 1 compounds
Identification
HMDB Protein ID CDBP01030
Secondary Accession Numbers Not Available
Name UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase
Description Not Available
Synonyms
  1. G1PT
  2. GPT
  3. GlcNAc-1-P transferase
  4. N-acetylglucosamine-1-phosphate transferase
Gene Name DPAGT1
Protein Type Enzyme
Biological Properties
General Function Involved in phospho-N-acetylmuramoyl-pentapeptide-transferase activity
Specific Function Catalyzes the initial step in the synthesis of dolichol-P-P-oligosaccharides.
GO Classification
Biological Process
dolichol biosynthetic process
dolichol-linked oligosaccharide biosynthetic process
post-translational protein modification
protein N-linked glycosylation via asparagine
protein oligomerization
UDP-N-acetylglucosamine metabolic process
Cellular Component
integral to endoplasmic reticulum membrane
Component
cell part
membrane part
intrinsic to membrane
integral to membrane
Function
catalytic activity
transferase activity
transferase activity, transferring phosphorus-containing groups
phosphotransferase activity, for other substituted phosphate groups
phospho-n-acetylmuramoyl-pentapeptide-transferase activity
Molecular Function
phospho-N-acetylmuramoyl-pentapeptide-transferase activity
UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity
transferase activity, transferring glycosyl groups
Cellular Location
  1. Endoplasmic reticulum membrane
  2. Multi-pass membrane protein
Pathways
Gene Properties
Chromosome Location 11
Locus 11q23.3
SNPs DPAGT1
Gene Sequence 
>1227 bp
ATGTGGGCCTTCTCGGAATTGCCCATGCCGCTGCTGATCAATTTGATCGTCTCGCTGCTG
GGATTTGTGGCCACAGTCACCCTCATCCCGGCCTTCCGGGGCCACTTCATTGCTGCGCGC
CTCTGTGGTCAGGACCTCAACAAAACCAGCCGACAGCAGATCCCAGAATCCCAGGGAGTG
ATCAGCGGTGCTGTTTTCCTTATCATCCTCTTCTGCTTCATCCCTTTCCCCTTCCTGAAC
TGCTTTGTGAAGGAGCAGTGTAAGGCATTCCCCCACCATGAATTTGTGGCCCTGATAGGT
GCCCTCCTTGCCATCTGCTGCATGATCTTCCTGGGCTTTGCGGATGATGTACTGAATCTG
CGCTGGCGCCATAAGCTGCTGCTACATACAGCTGCCTCACTACCTCTCCTCATGGTATAT
TTCACCAACTTTGGCAACACGACCATTGTGGTGCCCAAGCCTTTCCGCCCGATACTTGGC
CTGCATCTGGACTTGGGAATCCTGTACTATGTCTACATGGGGCTGCTGGCAGTGTTCTGT
ACCAATGCCATCAATATCCTAGCAGGAATTAACGGCCTAGAGGCTGGCCAGTCACTAGTC
ATTTCTGCTTCCATCATTGTCTTCAACCTGGTAGAGTTGGAAGGTGATTGTCGGGATGAT
CATGTCTTTTCCCTCTACTTCATGATACCCTTTTTTTTCACCACTTTGGGATTGCTCTAC
CACAACTGGTACCCATCACGGGTGTTTGTGGGAGATACCTTCTGTTACTTTGCTGGCATG
ACCTTTGCCGTGGTGGGCATCTTGGGACACTTCAGCAAGACCATGCTACTATTCTTCATG
CCCCAGGTGTTCAACTTCCTCTACTCACTGCCTCAGCTCCTGCATATCATCCCCTGCCCT
CGCCACCGCATACCCAGACTCAATATCAAGACAGGCAAACTGGAGATGAGCTATTCCAAG
TTCAAGACCAAGAGCCTCTCTTTCTTGGGCACCTTTATTTTAAAGGTGGCAGAGAGCCTC
CAGCTGGTGACAGTACACCAGAGTGAGACTGAAGATGGTGAATTCACTGAATGTAACAAC
ATGACCCTCATCAACTTGCTACTTAAAGTCCTTGGGCCCATACATGAGAGAAACCTCACA
TTGCTCCTGCTGCTGCTGCAGATCCTGGGCAGTGCCATCACCTTCTCCATTCGATATCAG
CTCGTTCGACTCTTCTATGATGTCTGA
Protein Properties
Number of Residues 408
Molecular Weight 46089.485
Theoretical pI 7.997
Pfam Domain Function
Signals Not Available
Transmembrane Regions Not Available
Protein Sequence 
>UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase
MWAFSELPMPLLINLIVSLLGFVATVTLIPAFRGHFIAARLCGQDLNKTSRQQIPESQGV
ISGAVFLIILFCFIPFPFLNCFVKEQCKAFPHHEFVALIGALLAICCMIFLGFADDVLNL
RWRHKLLLPTAASLPLLMVYFTNFGNTTIVVPKPFRPILGLHLDLGILYYVYMGLLAVFC
TNAINILAGINGLEAGQSLVISASIIVFNLVELEGDCRDDHVFSLYFMIPFFFTTLGLLY
HNWYPSRVFVGDTFCYFAGMTFAVVGILGHFSKTMLLFFMPQVFNFLYSLPQLLHIIPCP
RHRIPRLNIKTGKLEMSYSKFKTKSLSFLGTFILKVAESLQLVTVHQSETEDGEFTECNN
MTLINLLLKVLGPIHERNLTLLLLLLQILGSAITFSIRYQLVRLFYDV
GenBank ID Protein 12002052
UniProtKB/Swiss-Prot ID Q9H3H5
UniProtKB/Swiss-Prot Entry Name GPT_HUMAN
PDB IDs Not Available
GenBank Gene ID AF070443
GeneCard ID DPAGT1
GenAtlas ID DPAGT1
HGNC ID HGNC:2995
References
General References Not Available