| Identification |
|---|
| HMDB Protein ID
| CDBP00964 |
| Secondary Accession Numbers
| Not Available |
| Name
| Pantothenate kinase 3 |
| Description
| Not Available |
| Synonyms
|
- Pantothenic acid kinase 3
- hPanK3
|
| Gene Name
| PANK3 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in pantothenate kinase activity |
| Specific Function
| Plays a role in the physiological regulation of the intracellular CoA concentration (By similarity).
|
| GO Classification
|
| Biological Process |
| coenzyme A biosynthetic process |
| Cellular Component |
| cytoplasm |
| Function |
| catalytic activity |
| transferase activity |
| transferase activity, transferring phosphorus-containing groups |
| kinase activity |
| nucleoside binding |
| purine nucleoside binding |
| adenyl nucleotide binding |
| adenyl ribonucleotide binding |
| atp binding |
| pantothenate kinase activity |
| binding |
| Molecular Function |
| ATP binding |
| pantothenate kinase activity |
| Process |
| cofactor metabolic process |
| coenzyme metabolic process |
| metabolic process |
| coenzyme biosynthetic process |
| cellular metabolic process |
| coenzyme a biosynthetic process |
|
| Cellular Location
|
- Cytoplasm (Probable)
|
| Pathways
|
| Name | SMPDB/Pathwhiz | KEGG | | coenzyme A biosynthesis | Not Available | Not Available |
|
| Gene Properties |
|---|
| Chromosome Location
| 5 |
| Locus
| 5q34 |
| SNPs
| PANK3 |
| Gene Sequence
|
>1113 bp
ATGAAGATCAAAGATGCCAAGAAACCCTCTTTCCCATGGTTTGGCATGGACATTGGGGGA
ACTCTAGTAAAGCTCTCGTACTTTGAACCTATTGATATCACAGCAGAGGAAGAGCAAGAA
GAAGTTGAGAGTTTAAAAAGTATTCGGAAATATTTGACTTCTAACGTGGCATATGGATCC
ACCGGCATTCGGGATGTACACCTTGAACTGAAAGATTTAACACTTTTTGGCCGAAGAGGG
AACTTGCACTTTATCAGGTTTCCAACCCAGGACCTGCCTACTTTTATCCAAATGGGAAGA
GATAAAAACTTCTCAACATTGCAGACGGTGCTATGTGCTACAGGAGGTGGTGCTTACAAG
TTTGAAAAAGATTTTCGCACAATTGGAAACCTCCACCTGCACAAACTGGATGAACTTGAC
TGCCTTGTAAAGGGCTTGCTGTATATAGACTCTGTCAGTTTCAATGGACAAGCCGAGTGC
TATTATTTTGCTAATGCCTCAGAACCTGAGCGATGCCAAAAGATGCCTTTTAACCTGGAT
GATCCCTATCCACTGCTTGTAGTGAACATTGGCTCAGGAGTCAGTATTTTAGCAGTCCAT
TCCAAAGACAACTATAAACGAGTGACTGGGACAAGCCTTGGAGGGGGTACCTTTCTGGGT
TTATGCAGTTTATTGACTGGCTGTGAAAGTTTTGAAGAGGCTCTTGAAATGGCATCCAAA
GGTGATAGCACACAAGCTGACAAGCTGGTCCGTGATATTTATGGAGGAGATTATGAAAGA
TTTGGTTTGCCAGGTTGGGCTGTAGCATCTAGTTTTGGGAATATGATTTATAAGGAGAAG
CGAGAATCTGTTAGTAAAGAAGATCTGGCAAGAGCTACTTTAGTTACTATCACCAATAAC
ATTGGTTCTGTGGCACGAATGTGTGCTGTTAATGAGAAAATAAACAGAGTTGTCTTTGTT
GGAAACTTTTTACGTGTCAATACCCTCTCAATGAAACTTTTGGCATATGCACTGGATTAC
TGGTCAAAAGGTCAACTAAAAGCATTGTTTCTAGAACATGAGGGTTACTTTGGAGCAGTT
GGTGCACTTCTTGGGCTGCCAAATTTCAGCTAA
|
| Protein Properties |
|---|
| Number of Residues
| 370 |
| Molecular Weight
| 41093.695 |
| Theoretical pI
| 6.553 |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Pantothenate kinase 3
MKIKDAKKPSFPWFGMDIGGTLVKLSYFEPIDITAEEEQEEVESLKSIRKYLTSNVAYGS
TGIRDVHLELKDLTLFGRRGNLHFIRFPTQDLPTFIQMGRDKNFSTLQTVLCATGGGAYK
FEKDFRTIGNLHLHKLDELDCLVKGLLYIDSVSFNGQAECYYFANASEPERCQKMPFNLD
DPYPLLVVNIGSGVSILAVHSKDNYKRVTGTSLGGGTFLGLCSLLTGCESFEEALEMASK
GDSTQADKLVRDIYGGDYERFGLPGWAVASSFGNMIYKEKRESVSKEDLARATLVTITNN
IGSVARMCAVNEKINRVVFVGNFLRVNTLSMKLLAYALDYWSKGQLKALFLEHEGYFGAV
GALLGLPNFS
|
| External Links |
|---|
| GenBank ID Protein
| 10434655 |
| UniProtKB/Swiss-Prot ID
| Q9H999 |
| UniProtKB/Swiss-Prot Entry Name
| PANK3_HUMAN |
| PDB IDs
|
|
| GenBank Gene ID
| AK022961 |
| GeneCard ID
| PANK3 |
| GenAtlas ID
| PANK3 |
| HGNC ID
| HGNC:19365 |
| References |
|---|
| General References
| Not Available |