| Identification |
| HMDB Protein ID
| CDBP00950 |
| Secondary Accession Numbers
| Not Available |
| Name
| Cob(I)yrinic acid a,c-diamide adenosyltransferase, mitochondrial |
| Description
| Not Available |
| Synonyms
|
- Cob(I)alamin adenosyltransferase
- Methylmalonic aciduria type B protein
|
| Gene Name
| MMAB |
| Protein Type
| Enzyme |
| Biological Properties |
| General Function
| Involved in ATP binding |
| Specific Function
| Not Available |
| GO Classification
|
| Biological Process |
| cobalamin biosynthetic process |
| Cellular Component |
| mitochondrion |
| Function |
| binding |
| catalytic activity |
| transferase activity |
| nucleoside binding |
| purine nucleoside binding |
| adenyl nucleotide binding |
| adenyl ribonucleotide binding |
| atp binding |
| cob(i)yrinic acid a,c-diamide adenosyltransferase activity |
| transferase activity, transferring alkyl or aryl (other than methyl) groups |
| Molecular Function |
| ATP binding |
| cob(I)yrinic acid a,c-diamide adenosyltransferase activity |
| Process |
| tetrapyrrole metabolic process |
| porphyrin metabolic process |
| cobalamin biosynthetic process |
| porphyrin biosynthetic process |
| metabolic process |
| nitrogen compound metabolic process |
|
| Cellular Location
|
- Mitochondrion (Probable)
|
| Pathways
|
| Name | SMPDB/Pathwhiz | KEGG | | adenosylcobalamin biosynthesis | Not Available | Not Available | | Porphyrin and chlorophyll metabolism | Not Available |  |
|
| Gene Properties |
| Chromosome Location
| 12 |
| Locus
| 12q24 |
| SNPs
| MMAB |
| Gene Sequence
|
>753 bp
ATGGCTGTGTGCGGCCTGGGGAGCCGTCTTGGCCTGGGGAGCCGTCTTGGCCTGCAAGGG
TGCTTCGGCGCCGCCAGGCTCCTGTATCCCCGTTTCCAGAGCCGCGGCCCTCAGGGCGTG
GAAGACGGGGACAGGCCACAGCCTTCCTCGAAGACACCCAGGATCCCCAAGATTTACACC
AAAACGGGAGACAAAGGGTTTTCTAGTACCTTCACAGGAGAAAGGAGACCCAAAGATGAC
CAAGTGTTTGAAGCCGTGGGAACTACAGATGAATTAAGTTCAGCTATTGGGTTTGCTCTG
GAATTAGTCACAGAAAAGGGCCATACATTTGCCGAAGAGCTTCAGAAAATCCAGTGCACA
TTGCAGGACGTCGGCTCGGCCCTGGCGACACCATGCTCCTCGGCCCGGGAGGCTCACTTA
AAGTATACCACGTTCAAGGCGGGGCCCATCCTGGAGCTGGAGCAGTGGATCGACAAGTAC
ACCAGCCAGCTCCCACCACTCACGGCCTTCATCCTGCCTTCGGGAGGCAAGATCAGCTCG
GCGCTGCATTTCTGCCGGGCCGTGTGCCGCCGGGCCGAGAGACGTGTGGTGCCTCTTGTC
CAGATGGGAGAGACCGATGCGAACGTGGCCAAGTTCTTAAACAGACTCAGTGACTATCTC
TTCACGCTAGCCAGATATGCAGCCATGAAGGAGGGGAATCAAGAGAAAATATACAAGAAA
AATGACCCATCGGCCGAGTCTGAGGGACTCTGA
|
| Protein Properties |
| Number of Residues
| 250 |
| Molecular Weight
| 27387.975 |
| Theoretical pI
| 8.606 |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Cob(I)yrinic acid a,c-diamide adenosyltransferase, mitochondrial
MAVCGLGSRLGLGSRLGLRGCFGAARLLYPRFQSRGPQGVEDGDRPQPSSKTPRIPKIYT
KTGDKGFSSTFTGERRPKDDQVFEAVGTTDELSSAIGFALELVTEKGHTFAEELQKIQCT
LQDVGSALATPCSSAREAHLKYTTFKAGPILELEQWIDKYTSQLPPLTAFILPSGGKISS
ALHFCRAVCRRAERRVVPLVQMGETDANVAKFLNRLSDYLFTLARYAAMKEGNQEKIYMK
NDPSAESEGL
|
| External Links |
| GenBank ID Protein
| 127802458 |
| UniProtKB/Swiss-Prot ID
| Q96EY8 |
| UniProtKB/Swiss-Prot Entry Name
| MMAB_HUMAN |
| PDB IDs
|
|
| GenBank Gene ID
| BC005054 |
| GeneCard ID
| MMAB |
| GenAtlas ID
| MMAB |
| HGNC ID
| HGNC:19331 |
| References |
| General References
| Not Available |