| Identification |
|---|
| HMDB Protein ID
| CDBP00897 |
| Secondary Accession Numbers
| Not Available |
| Name
| DNA polymerase epsilon subunit 4 |
| Description
| Not Available |
| Synonyms
|
- DNA polymerase II subunit 4
- DNA polymerase epsilon subunit p12
|
| Gene Name
| POLE4 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in sequence-specific DNA binding |
| Specific Function
| May play a role in allowing polymerase epsilon to carry out its replication and/or repair function.
|
| GO Classification
|
| Biological Process |
| histone H3 acetylation |
| Cellular Component |
| epsilon DNA polymerase complex |
| Ada2/Gcn5/Ada3 transcription activator complex |
| Component |
| cell part |
| intracellular |
| Function |
| binding |
| nucleic acid binding |
| dna binding |
| sequence-specific dna binding |
| Molecular Function |
| sequence-specific DNA binding |
| DNA-directed DNA polymerase activity |
|
| Cellular Location
|
- Nucleus (Potential)
|
| Pathways
|
| Name | SMPDB/Pathwhiz | KEGG | | DNA replication | Not Available |  | | Base excision repair | Not Available |  | | HTLV-I infection | Not Available |  |
|
| Gene Properties |
|---|
| Chromosome Location
| 2 |
| Locus
| 2p12 |
| SNPs
| POLE4 |
| Gene Sequence
|
>354 bp
ATGGCGGCGGCGGCGGCGGCAGGAAGCGGGACGCCCCGAGAGGAGGAGGGACCTGCTGGG
GAGGCAGCGGCCTCGCAGCCCCAGGCCCCAACGAGTGTGCCTGGGGCTCGTCTCTCGAGG
TTGCCTCTGGCGCGAGTGAAGGCCTTGGTGAAGGCAGATCCCGACGTGACGCTAGCGGGA
CAGGAAGCCATCTTCATTCTGGCACGAGCCGCGGAACTGTTTGTGGAGACCATTGCAAAA
GATGCCTACTGTTGCGCTCAGCAGGGAAAAAGGAAAACCCTTCAGAGGAGAGACTTGGAT
AATGCAATAGAAGCTGTGGATGAATTTGCTTTTCTGGAAGGTACTTTAGATTGA
|
| Protein Properties |
|---|
| Number of Residues
| 117 |
| Molecular Weight
| 12208.63 |
| Theoretical pI
| 4.914 |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>DNA polymerase epsilon subunit 4
MAAAAAAGSGTPREEEGPAGEAAASQPQAPTSVPGARLSRLPLARVKALVKADPDVTLAG
QEAIFILARAAELFVETIAKDAYCCAQQGKRKTLQRRDLDNAIEAVDEFAFLEGTLD
|
| External Links |
|---|
| GenBank ID Protein
| 62822482 |
| UniProtKB/Swiss-Prot ID
| Q9NR33 |
| UniProtKB/Swiss-Prot Entry Name
| DPOE4_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AC007400 |
| GeneCard ID
| POLE4 |
| GenAtlas ID
| POLE4 |
| HGNC ID
| HGNC:18755 |
| References |
|---|
| General References
| Not Available |