Cannabis Compound Database: Showing Protein Ornithine carbamoyltransferase, mitochondrial (CDBP00870)

Identification Biological properties Gene properties Protein properties External links References XML Show 3 compounds

Identification

HMDB Protein ID

CDBP00870

Secondary Accession Numbers

Not Available

Name

Ornithine carbamoyltransferase, mitochondrial

Description

Not Available

Synonyms

OTCase
Ornithine transcarbamylase

Gene Name

OTC

Protein Type

Enzyme

Biological Properties

General Function

Involved in carboxyl- or carbamoyltransferase activity

Specific Function

Not Available

GO Classification

Biological Process
liver development
response to drug
response to biotin
anion homeostasis
citrulline biosynthetic process
midgut development
protein homotrimerization
urea cycle
response to zinc ion
arginine biosynthetic process
response to insulin stimulus
Cellular Component
mitochondrial matrix
ornithine carbamoyltransferase complex
mitochondrial inner membrane
Component
ornithine carbamoyltransferase complex
macromolecular complex
protein complex
Function
transferase activity
ornithine carbamoyltransferase activity
carboxyl- or carbamoyltransferase activity
carboxylic acid binding
amino acid binding
transferase activity, transferring one-carbon groups
binding
catalytic activity
Molecular Function
ornithine carbamoyltransferase activity
phospholipid binding
phosphate ion binding
amino acid binding
Process
metabolic process
cellular metabolic process
cellular amino acid and derivative metabolic process
cellular amino acid metabolic process

Cellular Location

Mitochondrion matrix

Pathways

Name	SMPDB/Pathwhiz	KEGG
Arginine and Proline Metabolism
Urea Cycle
Prolidase Deficiency (PD)		Not Available
Arginine: Glycine Amidinotransferase Deficiency (AGAT Deficiency)		Not Available
Hyperprolinemia Type II		Not Available

Gene Properties

Chromosome Location

Locus

Xp21.1

SNPs

OTC

Gene Sequence

>1065 bp
ATGCTGTTTAATCTGAGGATCCTGTTAAACAATGCAGCTTTTAGAAATGGTCACAACTTC
ATGGTTCGAAATTTTCGGTGTGGACAACCACTACAAAATAAAGTGCAGCTGAAGGGCCGT
GACCTTCTCACTCTAAAAAACTTTACCGGAGAAGAAATTAAATATATGCTATGGCTATCA
GCAGATCTGAAATTTAGGATAAAACAGAAAGGAGAGTATTTGCCTTTATTGCAGGGGAAG
TCCTTAGGCATGATTTTTGAGAAAAGAAGTACTCGAACAAGATTGTCTACAGAAACAGGC
TTTGCACTTCTGGGAGGACATCCTTGTTTTCCTACCACACAAGATATTCATTTGGGTGTG
AATGAAAGTCTCACGGACACGGCCCGTGTATTGTCTAGCATGGCAGATGCAGTATTGGCT
CGAGTGTATAAACAATCAGATTTGGACACCCTTGCTAAAGAAGCATCCATCCCAATTATC
AATGGGCTGTCAGATTTGTACCATCCTATCCAGATCCTGGCTGATTACCTCACGCTCCAG
GAACACTATAGCTCTCTGAAAGGTCTTACCCTCAGCTGTTTCGGGGATGGGAACAATATC
CTGCACTCCATCATGATGAGCGCAGCGAAATTCGGAATGCACCTTCAGGCAGCTACTCCA
AAGGGTTATGAGCCGGATGCTAGTGTAACCAAGTTGGCAGAGCAGTATGCCAAAGAGAAT
GGTACCAAGCTGTTGCTGACAAATGATCCATTGGAAGCAGCGCATGGAGGCAATGTATTA
ATTACAGACACTTGGATAAGCATGGGACGAGAAGAGGAGAAGAAAAAGCGGCTCCAAGCT
TTCCAAGGTTACCAAGTTACAATGAAGACTGCTAAAGTTGCTGCCTCTGACTGGACATTT
TTACACTGCTTGCCCAGAAAGCCAGAAGAAGTGGATGATGAAGTCTTTTATTCTCCTCGA
TCACTAGTGTTCCCAGAGGCAGAAAACAGAAAGTGGACAATCATGGCTGTCATGGTGTCC
CTGCTGACAGATTACTCACCTCAGCTCCAGAAGCCTAAATTTTGA

Protein Properties

Number of Residues

354

Molecular Weight

39934.775

Theoretical pI

8.633

Pfam Domain Function

OTCace (PF00185 )
OTCace_N (PF02729 )

Signals

Not Available

Transmembrane Regions

Not Available

Protein Sequence

>Ornithine carbamoyltransferase, mitochondrial
MLFNLRILLNNAAFRNGHNFMVRNFRCGQPLQNKVQLKGRDLLTLKNFTGEEIKYMLWLS
ADLKFRIKQKGEYLPLLQGKSLGMIFEKRSTRTRLSTETGFALLGGHPCFLTTQDIHLGV
NESLTDTARVLSSMADAVLARVYKQSDLDTLAKEASIPIINGLSDLYHPIQILADYLTLQ
EHYSSLKGLTLSWIGDGNNILHSIMMSAAKFGMHLQAATPKGYEPDASVTKLAEQYAKEN
GTKLLLTNDPLEAAHGGNVLITDTWISMGQEEEKKKRLQAFQGYQVTMKTAKVAASDWTF
LHCLPRKPEEVDDEVFYSPRSLVFPEAENRKWTIMAVMVSLLTDYSPQLQKPKF

External Links

GenBank ID Protein

189407

UniProtKB/Swiss-Prot ID

P00480

UniProtKB/Swiss-Prot Entry Name

OTC_HUMAN

PDB IDs