Cannabis Compound Database: Showing Protein Glutathione S-transferase Mu 3 (CDBP00760)

Identification Biological properties Gene properties Protein properties External links References XML Show 4 compounds

Identification

HMDB Protein ID

CDBP00760

Secondary Accession Numbers

Not Available

Name

Glutathione S-transferase Mu 3

Description

Not Available

Synonyms

GST class-mu 3
GSTM3-3
hGSTM3-3

Gene Name

GSTM3

Protein Type

Enzyme

Biological Properties

General Function

Involved in glutathione transferase activity

Specific Function

Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. May govern uptake and detoxification of both endogenous compounds and xenobiotics at the testis and brain blood barriers.

GO Classification

Biological Process
glutathione metabolic process
xenobiotic catabolic process
response to estrogen stimulus
cellular detoxification of nitrogen compound
nitrobenzene metabolic process
establishment of blood-nerve barrier
Cellular Component
cytoplasm
Function
catalytic activity
transferase activity
transferase activity, transferring alkyl or aryl (other than methyl) groups
glutathione transferase activity
Molecular Function
glutathione binding
glutathione transferase activity
protein homodimerization activity
Process
metabolic process

Cellular Location

Cytoplasm

Pathways

Name	SMPDB/Pathwhiz	KEGG
Metabolism of xenobiotics by cytochrome P450	Not Available
Drug metabolism - cytochrome P450	Not Available
Chemical carcinogenesis	Not Available

Gene Properties

Chromosome Location

Locus

1p13.3

SNPs

GSTM3

Gene Sequence

>678 bp
ATGTCGTGCGAGTCGTCTATGGTTCTCGGGTACTGGGATATTCGTGGGCTGGCGCACGCC
ATCCGCCTGCTCCTGGAGTTCACGGATACCTCTTATGAGGAGAAACGGTACACGTGCGGG
GAAGCTCCTGACTATGATCGAAGCCAATGGCTGGATGTGAAATTCAAGCTAGACCTGGAC
TTTCCTAATCTGCCCTACCTCCTGGATGGGAAGAACAAGATCACCCAGAGCAATGCCATC
TTGCGCTACATCGCTCGCAAGCACAACATGTGTGGTGAGACTGAAGAAGAAAAGATTCGA
GTGGACATCATAGAGAACCAAGTAATGGATTTCCGCACACAACTGATAAGGCTCTGTTAC
AGCTCTGACCACGAAAAACTGAAGCCTCAGTACTTGGAAGAGCTACCTGGACAACTGAAA
CAATTCTCCATGTTTCTGTGGAAATTCTCATGGTTTGCCGGGGAAAAGCTCACCTTTGTG
GATTTTCTCACCTATGATATCTTGGATCAGAACCGTATATTTGACCCCAAGTGCCTGGAT
GAGTTCCCAAACCTGAAGGCTTTCATGTGCCGTTTTGAGGCTTTGGAGAAAATCGCTGCC
TACTTACAGTCTGATCAGTTCTGCAAGATGCCCATCAACAACAAGATGGCCCAGTGGGGC
AACAAGCCTGTATGCTGA

Protein Properties

Number of Residues

225

Molecular Weight

26559.32

Theoretical pI

5.538

Pfam Domain Function

GST_C (PF00043 )
GST_N (PF02798 )

Signals

Not Available

Transmembrane Regions

Not Available

Protein Sequence

>Glutathione S-transferase Mu 3
MSCESSMVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLD
FPNLPYLLDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCY
SSDHEKLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDPKCLD
EFPNLKAFMCRFEALEKIAAYLQSDQFCKMPINNKMAQWGNKPVC

External Links

GenBank ID Protein

306820

UniProtKB/Swiss-Prot ID

P21266

UniProtKB/Swiss-Prot Entry Name

GSTM3_HUMAN

PDB IDs